Assessment of Bisphenol A (BPA) Exposure in Dairy Cows Using Hair Samples Analysis
Bisphenol A (BPA) is a plasticizer known to have various adverse effects on humans and animals. Exposure of farm animals to BPA negatively impacts their health and poses a threat to humans who consume products of animal origin. Despite the importance of studying the exposure of farm animals to BPA,...
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MDPI AG
2025-03-01
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| author | Slawomir Gonkowski Manolis Tzatzarakis Nariste Kadyralieva Elena Vakonaki Thomas Lamprakis Ismail Sen Askarbek Tulobaev Fatih R. Istanbullugil Aidai Zhunushova Liliana Rytel |
| author_facet | Slawomir Gonkowski Manolis Tzatzarakis Nariste Kadyralieva Elena Vakonaki Thomas Lamprakis Ismail Sen Askarbek Tulobaev Fatih R. Istanbullugil Aidai Zhunushova Liliana Rytel |
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| description | Bisphenol A (BPA) is a plasticizer known to have various adverse effects on humans and animals. Exposure of farm animals to BPA negatively impacts their health and poses a threat to humans who consume products of animal origin. Despite the importance of studying the exposure of farm animals to BPA, the knowledge in this area is quite limited. To date, the assessment of BPA levels in dairy cows using analysis of hair samples has not been performed. The study utilized liquid chromatography-mass spectrometry to analyze hair samples collected from 48 dairy cows in the following regions of Kyrgyzstan: Sokuluk, Alamedin and Ysyk Ata. BPA levels above the limit of detection (LOD = 4.8 pg/mg) were noted in 18.8% of analyzed samples. BPA levels in individual samples ranged from below LOD to 89.1 pg/mg with a median value of 9.3 ± 19.7 pg/mg. The study indicates that dairy cows are exposed to BPA, and hair samples can be used for BPA biomonitoring in farm animals. The present study is the first investigation of BPA levels in cows’ hair, which is one of the best matrices to study long-term exposure of living organisms to environmental pollutants. Additionally, this study is the first to analyze BPA in biological samples from Kyrgyzstan. |
| format | Article |
| id | doaj-art-bc9f352f40fb4e43a0eeac593a6ce5bd |
| institution | DOAJ |
| issn | 2076-2615 |
| language | English |
| publishDate | 2025-03-01 |
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| spelling | doaj-art-bc9f352f40fb4e43a0eeac593a6ce5bd2025-08-20T03:06:32ZengMDPI AGAnimals2076-26152025-03-0115793910.3390/ani15070939Assessment of Bisphenol A (BPA) Exposure in Dairy Cows Using Hair Samples AnalysisSlawomir Gonkowski0Manolis Tzatzarakis1Nariste Kadyralieva2Elena Vakonaki3Thomas Lamprakis4Ismail Sen5Askarbek Tulobaev6Fatih R. Istanbullugil7Aidai Zhunushova8Liliana Rytel9Department of Clinical Physiology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10-957 Olsztyn, PolandLaboratory of Toxicology, School of Medicine, University of Crete, 70013 Heraklion, GreeceDepartment of Histology and Embryology, Faculty of Veterinary Medicine, Kyrgyz-Turkish Manas University, Bishkek 720042, KyrgyzstanLaboratory of Toxicology, School of Medicine, University of Crete, 70013 Heraklion, GreeceLaboratory of Toxicology, School of Medicine, University of Crete, 70013 Heraklion, GreeceDepartment of Internal Medicine Faculty of Veterinary Medicine, Kyrgyz-Turkish Manas University, Bishkek 720042, KyrgyzstanDepartment of Basic Science, Faculty of Veterinary Medicine, Kyrgyz-Turkish Manas University, Bishkek 720042, KyrgyzstanDepartment of Food Hygiene and Technology, Faculty of Veterinary Medicine, Kyrgyz-Turkish Manas University, Bishkek 720042, KyrgyzstanDepartment of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Kyrgyz-Turkish Manas University, Bishkek 720042, KyrgyzstanDepartment of Internal Diseases with Clinics, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-720 Olsztyn, PolandBisphenol A (BPA) is a plasticizer known to have various adverse effects on humans and animals. Exposure of farm animals to BPA negatively impacts their health and poses a threat to humans who consume products of animal origin. Despite the importance of studying the exposure of farm animals to BPA, the knowledge in this area is quite limited. To date, the assessment of BPA levels in dairy cows using analysis of hair samples has not been performed. The study utilized liquid chromatography-mass spectrometry to analyze hair samples collected from 48 dairy cows in the following regions of Kyrgyzstan: Sokuluk, Alamedin and Ysyk Ata. BPA levels above the limit of detection (LOD = 4.8 pg/mg) were noted in 18.8% of analyzed samples. BPA levels in individual samples ranged from below LOD to 89.1 pg/mg with a median value of 9.3 ± 19.7 pg/mg. The study indicates that dairy cows are exposed to BPA, and hair samples can be used for BPA biomonitoring in farm animals. The present study is the first investigation of BPA levels in cows’ hair, which is one of the best matrices to study long-term exposure of living organisms to environmental pollutants. Additionally, this study is the first to analyze BPA in biological samples from Kyrgyzstan.https://www.mdpi.com/2076-2615/15/7/939dairy cowsbisphenol Aendocrine disruptorsexposure |
| spellingShingle | Slawomir Gonkowski Manolis Tzatzarakis Nariste Kadyralieva Elena Vakonaki Thomas Lamprakis Ismail Sen Askarbek Tulobaev Fatih R. Istanbullugil Aidai Zhunushova Liliana Rytel Assessment of Bisphenol A (BPA) Exposure in Dairy Cows Using Hair Samples Analysis Animals dairy cows bisphenol A endocrine disruptors exposure |
| title | Assessment of Bisphenol A (BPA) Exposure in Dairy Cows Using Hair Samples Analysis |
| title_full | Assessment of Bisphenol A (BPA) Exposure in Dairy Cows Using Hair Samples Analysis |
| title_fullStr | Assessment of Bisphenol A (BPA) Exposure in Dairy Cows Using Hair Samples Analysis |
| title_full_unstemmed | Assessment of Bisphenol A (BPA) Exposure in Dairy Cows Using Hair Samples Analysis |
| title_short | Assessment of Bisphenol A (BPA) Exposure in Dairy Cows Using Hair Samples Analysis |
| title_sort | assessment of bisphenol a bpa exposure in dairy cows using hair samples analysis |
| topic | dairy cows bisphenol A endocrine disruptors exposure |
| url | https://www.mdpi.com/2076-2615/15/7/939 |
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