ACE2 and TMPRSS2 gene expression is reduced acutely in SARS-CoV-2 patients but returns to normal with recovery

ACE2 and TMPRSS2 gene expression is reduced acutely in SARS-CoV-2 patients but returns to normal with recovery

Abstract During the SARS-CoV-2 pandemic, angiotensin-converting enzyme 2 (ACE2) was identified as the major entry receptor for the virus and transmembrane serine protease 2 (TMPRSS2) as an important SARS-CoV-2 entry factor. Previous studies investigating the impact of ACE2 and TMPRSS2 gene expressio...

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Bibliographic Details
Main Authors: Vanessa Hui En Chen, Joshua K. Tay, Rijan Gurung, Smeetha Nair, Douglas Jie Wen Tay, Kai Sen Tan, Roger S. Y. Foo, Paul A. Tambyah
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
SARS CoV-2
ACE2
TMPRSS2
Online Access:https://doi.org/10.1038/s41598-025-96279-x
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