Fibroblast Growth Factor Receptor 4 Promotes Triple‐Negative Breast Cancer Progression via Regulating Fatty Acid Metabolism Through the AKT/RYR2 Signaling

Fibroblast Growth Factor Receptor 4 Promotes Triple‐Negative Breast Cancer Progression via Regulating Fatty Acid Metabolism Through the AKT/RYR2 Signaling

ABSTRACT Background Triple‐negative breast cancer (TNBC) is the most aggressive subtype of breast cancer. Previous studies have found that fibroblast growth factor receptor 4 (FGFR4) plays a crucial role in tumor development and metastasis. However, the potential role and underlying mechanisms of FG...

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Bibliographic Details
Main Authors: Jinhui Ye, Song Wu, Qiang Quan, Feng Ye, Jinhui Zhang, Cailu Song, Yidan Fan, Huijiao Cao, Hailin Tang, Jianfu Zhao
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Cancer Medicine
Subjects:
AKT
fatty acid metabolism
FGFR4
RyR2
TNBC
Online Access:https://doi.org/10.1002/cam4.70439
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