Anamnesis peculiarities of BRCA1-associated breast cancer in young women
A group of reproductive age patients whose disease is associated with the carriage of BRCA1 gene mutation is of scientific interest. Differences in the molecular pathogenesis between BRCA-associated breast cancer and sporadic counterpart might presuppose anamnesis features of each group as well. We...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
ABV-press
2014-07-01
|
| Series: | Опухоли женской репродуктивной системы |
| Subjects: | |
| Online Access: | https://ojrs.abvpress.ru/ojrs/article/view/115 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849303265536114688 |
|---|---|
| author | D. E. Avtomonov A. A. Parokonnaya L. N. Lyubchenko M. I. Nechushkin D. N. Kravchenko |
| author_facet | D. E. Avtomonov A. A. Parokonnaya L. N. Lyubchenko M. I. Nechushkin D. N. Kravchenko |
| author_sort | D. E. Avtomonov |
| collection | DOAJ |
| description | A group of reproductive age patients whose disease is associated with the carriage of BRCA1 gene mutation is of scientific interest. Differences in the molecular pathogenesis between BRCA-associated breast cancer and sporadic counterpart might presuppose anamnesis features of each group as well. We have ascertained that the mean age in young age patients with positive BRCA1 status is 31.8 ± 3.3 years, in 40 % of cases in the family history in the 1st and 2 nd order relatives a breast cancer was identified, in 40 % of cases breast cancer was diagnosed during pregnancy, breast feeding or 1 year post-pregnancy, the disease course in young BRCA1-positive patients is characterized by a 30 % risk of contralateral breast cancer during the first 5 years of observation. |
| format | Article |
| id | doaj-art-bc8f55dd311240e8b4b8af8da13de853 |
| institution | Kabale University |
| issn | 1994-4098 1999-8627 |
| language | Russian |
| publishDate | 2014-07-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Опухоли женской репродуктивной системы |
| spelling | doaj-art-bc8f55dd311240e8b4b8af8da13de8532025-08-20T04:00:02ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272014-07-0103-4545710.17650/1994-4098-2012-0-3-4-54-57131Anamnesis peculiarities of BRCA1-associated breast cancer in young womenD. E. Avtomonov0A. A. Parokonnaya1L. N. Lyubchenko2M. I. Nechushkin3D. N. Kravchenko4Research Institute of Clinical Oncology N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowResearch Institute of Clinical Oncology N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowResearch Institute of Clinical Oncology N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowResearch Institute of Clinical Oncology N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowResearch Institute of Clinical Oncology N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowA group of reproductive age patients whose disease is associated with the carriage of BRCA1 gene mutation is of scientific interest. Differences in the molecular pathogenesis between BRCA-associated breast cancer and sporadic counterpart might presuppose anamnesis features of each group as well. We have ascertained that the mean age in young age patients with positive BRCA1 status is 31.8 ± 3.3 years, in 40 % of cases in the family history in the 1st and 2 nd order relatives a breast cancer was identified, in 40 % of cases breast cancer was diagnosed during pregnancy, breast feeding or 1 year post-pregnancy, the disease course in young BRCA1-positive patients is characterized by a 30 % risk of contralateral breast cancer during the first 5 years of observation.https://ojrs.abvpress.ru/ojrs/article/view/115breast canceryoung agebrca1/2anamnesis peculiarities |
| spellingShingle | D. E. Avtomonov A. A. Parokonnaya L. N. Lyubchenko M. I. Nechushkin D. N. Kravchenko Anamnesis peculiarities of BRCA1-associated breast cancer in young women Опухоли женской репродуктивной системы breast cancer young age brca1/2 anamnesis peculiarities |
| title | Anamnesis peculiarities of BRCA1-associated breast cancer in young women |
| title_full | Anamnesis peculiarities of BRCA1-associated breast cancer in young women |
| title_fullStr | Anamnesis peculiarities of BRCA1-associated breast cancer in young women |
| title_full_unstemmed | Anamnesis peculiarities of BRCA1-associated breast cancer in young women |
| title_short | Anamnesis peculiarities of BRCA1-associated breast cancer in young women |
| title_sort | anamnesis peculiarities of brca1 associated breast cancer in young women |
| topic | breast cancer young age brca1/2 anamnesis peculiarities |
| url | https://ojrs.abvpress.ru/ojrs/article/view/115 |
| work_keys_str_mv | AT deavtomonov anamnesispeculiaritiesofbrca1associatedbreastcancerinyoungwomen AT aaparokonnaya anamnesispeculiaritiesofbrca1associatedbreastcancerinyoungwomen AT lnlyubchenko anamnesispeculiaritiesofbrca1associatedbreastcancerinyoungwomen AT minechushkin anamnesispeculiaritiesofbrca1associatedbreastcancerinyoungwomen AT dnkravchenko anamnesispeculiaritiesofbrca1associatedbreastcancerinyoungwomen |