Gastrointestinal Tract Duplications in Children: A Tertiary Referral Center Experience
Objective: Gastrointestinal duplications are rare congenital anomalies. Herein, we present a single institutional experience in pediatric gastrointestinal tract duplications. Methods: Patient records from 2014 to 2019 were retrospectively evaluated for demographic data, clinical presentation, diagno...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2022-06-01
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| Series: | Medeniyet Medical Journal |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-46383 |
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| author | Meltem CAGLAR OSKAYLI Furkan ERSOY Neslihan GULCIN Ahmet PIRIM Seyhmus Kerem OZEL Seyma OZKANLI Cigdem ULUKAYA DURAKBASA |
| author_facet | Meltem CAGLAR OSKAYLI Furkan ERSOY Neslihan GULCIN Ahmet PIRIM Seyhmus Kerem OZEL Seyma OZKANLI Cigdem ULUKAYA DURAKBASA |
| author_sort | Meltem CAGLAR OSKAYLI |
| collection | DOAJ |
| description | Objective: Gastrointestinal duplications are rare congenital anomalies. Herein, we present a single institutional experience in pediatric gastrointestinal tract duplications.
Methods: Patient records from 2014 to 2019 were retrospectively evaluated for demographic data, clinical presentation, diagnostic methods, surgical findings, and pathological reports.
Results: This study included 19 patients, of whom 10 were males and nine were females, with a median age of 30 (21 days-15.5 years) months. Three patients were antenatally and three were incidentally diagnosed. Abdominal pain, vomiting, constipation, and perianal accessory orifice were the most common presenting symptoms. Preoperative diagnostic workup included ultrasonography (n=13), cross-sectional imaging (n=8), and nuclear scintigraphy (n=1). A preoperative diagnosis was possible in 14 (74%) patients. The duplications originated from the foregut in seven (37%) patients, midgut in seven (37%), and hindgut in five (26%). Cystic duplications were observed in 14 (74%) patients and tubular in five (26%). The total surgical excision with (n=8) or without (n=10) associated organ resection was possible in 18 patients. Partial cyst excision with a complete mucosal removal was done in 1 patient. Heterotopic mucosa was present in six (32%) specimens. The respiratory origin with thyroid transcription factor-1 positivity was contained in two para-esophageal duplications. Among five patients with heterotopic gastric mucosa, 1 had presented with perforation and the others with hemorrhage.
Conclusions: Duplications may involve any gastrointestinal segment. The clinical presentation is highly variable because of the wide variation in the involved segment and sizes and the possibility of bearing heterotopic mucosa. The surgery aims to totally excise the cyst or at least totally remove the inner mucosal lining. |
| format | Article |
| id | doaj-art-bc8d014f6c6241a2b1a68ed90d59887e |
| institution | Kabale University |
| issn | 2149-2042 2149-4606 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Medeniyet Medical Journal |
| spelling | doaj-art-bc8d014f6c6241a2b1a68ed90d59887e2025-01-30T07:13:14ZengGalenos Publishing HouseMedeniyet Medical Journal2149-20422149-46062022-06-0137213714410.4274/MMJ.galenos.2022.46383MEDJ-46383Gastrointestinal Tract Duplications in Children: A Tertiary Referral Center ExperienceMeltem CAGLAR OSKAYLI0Furkan ERSOY1Neslihan GULCIN2Ahmet PIRIM3Seyhmus Kerem OZEL4Seyma OZKANLI5Cigdem ULUKAYA DURAKBASA6Istanbul Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Clinic of Pediatric Surgery, Istanbul, TurkeyIstanbul Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Clinic of Pediatric Surgery, Istanbul, TurkeyIstanbul Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Clinic of Pediatric Surgery, Istanbul, TurkeyIstanbul Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Clinic of Pediatric Surgery, Istanbul, TurkeyIstanbul Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Clinic of Pediatric Surgery, Istanbul, TurkeyIstanbul Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Clinic of Pathology, Istanbul, TurkeyIstanbul Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Clinic of Pediatric Surgery, Istanbul, TurkeyObjective: Gastrointestinal duplications are rare congenital anomalies. Herein, we present a single institutional experience in pediatric gastrointestinal tract duplications. Methods: Patient records from 2014 to 2019 were retrospectively evaluated for demographic data, clinical presentation, diagnostic methods, surgical findings, and pathological reports. Results: This study included 19 patients, of whom 10 were males and nine were females, with a median age of 30 (21 days-15.5 years) months. Three patients were antenatally and three were incidentally diagnosed. Abdominal pain, vomiting, constipation, and perianal accessory orifice were the most common presenting symptoms. Preoperative diagnostic workup included ultrasonography (n=13), cross-sectional imaging (n=8), and nuclear scintigraphy (n=1). A preoperative diagnosis was possible in 14 (74%) patients. The duplications originated from the foregut in seven (37%) patients, midgut in seven (37%), and hindgut in five (26%). Cystic duplications were observed in 14 (74%) patients and tubular in five (26%). The total surgical excision with (n=8) or without (n=10) associated organ resection was possible in 18 patients. Partial cyst excision with a complete mucosal removal was done in 1 patient. Heterotopic mucosa was present in six (32%) specimens. The respiratory origin with thyroid transcription factor-1 positivity was contained in two para-esophageal duplications. Among five patients with heterotopic gastric mucosa, 1 had presented with perforation and the others with hemorrhage. Conclusions: Duplications may involve any gastrointestinal segment. The clinical presentation is highly variable because of the wide variation in the involved segment and sizes and the possibility of bearing heterotopic mucosa. The surgery aims to totally excise the cyst or at least totally remove the inner mucosal lining.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-46383gastrointestinalduplication cystheterotopic mucosarespiratory epitheliumsurgery |
| spellingShingle | Meltem CAGLAR OSKAYLI Furkan ERSOY Neslihan GULCIN Ahmet PIRIM Seyhmus Kerem OZEL Seyma OZKANLI Cigdem ULUKAYA DURAKBASA Gastrointestinal Tract Duplications in Children: A Tertiary Referral Center Experience Medeniyet Medical Journal gastrointestinal duplication cyst heterotopic mucosa respiratory epithelium surgery |
| title | Gastrointestinal Tract Duplications in Children: A Tertiary Referral Center Experience |
| title_full | Gastrointestinal Tract Duplications in Children: A Tertiary Referral Center Experience |
| title_fullStr | Gastrointestinal Tract Duplications in Children: A Tertiary Referral Center Experience |
| title_full_unstemmed | Gastrointestinal Tract Duplications in Children: A Tertiary Referral Center Experience |
| title_short | Gastrointestinal Tract Duplications in Children: A Tertiary Referral Center Experience |
| title_sort | gastrointestinal tract duplications in children a tertiary referral center experience |
| topic | gastrointestinal duplication cyst heterotopic mucosa respiratory epithelium surgery |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-46383 |
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