The Oral Microbiome of Peri-Implant Health and Disease: A Narrative Review

Peri-implantitis disease has increased significantly over the last years, resulting in increased failure of implants. Many factors may play a role in implant complications and failure, including ones related to the oral microbiota. This literature review aims to summarize the current knowledge of mi...

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Main Authors: Natalia de Campos Kajimoto, Yvonne de Paiva Buischi, Mansour Mohamadzadeh, Peter Loomer
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Dentistry Journal
Subjects:
Online Access:https://www.mdpi.com/2304-6767/12/10/299
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author Natalia de Campos Kajimoto
Yvonne de Paiva Buischi
Mansour Mohamadzadeh
Peter Loomer
author_facet Natalia de Campos Kajimoto
Yvonne de Paiva Buischi
Mansour Mohamadzadeh
Peter Loomer
author_sort Natalia de Campos Kajimoto
collection DOAJ
description Peri-implantitis disease has increased significantly over the last years, resulting in increased failure of implants. Many factors may play a role in implant complications and failure, including ones related to the oral microbiota. This literature review aims to summarize the current knowledge of microbiome of implants in health and disease, focusing not only on the presence/absence of specific microbiota or on their relative abundance, but also on their phenotypic expression and their complex relationships with the host. The authors examined the MEDLINE database and identified key topics about peri-implant oral microbiome in health and disease. The peri-implant microbiome differs from that of the tooth, both in health and disease, as they are structurally and chemically different. The adhesion and formation of the peri-implant biofilm can be affected by the surface energy, topography, wettability, and electrochemical charges of the implant surface. In addition, the morphogenesis of the tissues surrounding the dental implant also differs from the tooth, making the dental implant more susceptible to bacterial infection. This interplay between the microbiome and the host immune system in peri-implant infections still needs to be elucidated.
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spelling doaj-art-bc8bf4dd3eed42d194086998a46cb47b2025-08-20T02:10:59ZengMDPI AGDentistry Journal2304-67672024-09-01121029910.3390/dj12100299The Oral Microbiome of Peri-Implant Health and Disease: A Narrative ReviewNatalia de Campos Kajimoto0Yvonne de Paiva Buischi1Mansour Mohamadzadeh2Peter Loomer3Department of Periodontics, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USADepartment of Periodontics, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USADepartment of Microbiology, Immunology & Molecular Genetics, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USADepartment of Periodontics, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USAPeri-implantitis disease has increased significantly over the last years, resulting in increased failure of implants. Many factors may play a role in implant complications and failure, including ones related to the oral microbiota. This literature review aims to summarize the current knowledge of microbiome of implants in health and disease, focusing not only on the presence/absence of specific microbiota or on their relative abundance, but also on their phenotypic expression and their complex relationships with the host. The authors examined the MEDLINE database and identified key topics about peri-implant oral microbiome in health and disease. The peri-implant microbiome differs from that of the tooth, both in health and disease, as they are structurally and chemically different. The adhesion and formation of the peri-implant biofilm can be affected by the surface energy, topography, wettability, and electrochemical charges of the implant surface. In addition, the morphogenesis of the tissues surrounding the dental implant also differs from the tooth, making the dental implant more susceptible to bacterial infection. This interplay between the microbiome and the host immune system in peri-implant infections still needs to be elucidated.https://www.mdpi.com/2304-6767/12/10/299microbiotaperi-implantitisdental implantsdysbiosis
spellingShingle Natalia de Campos Kajimoto
Yvonne de Paiva Buischi
Mansour Mohamadzadeh
Peter Loomer
The Oral Microbiome of Peri-Implant Health and Disease: A Narrative Review
Dentistry Journal
microbiota
peri-implantitis
dental implants
dysbiosis
title The Oral Microbiome of Peri-Implant Health and Disease: A Narrative Review
title_full The Oral Microbiome of Peri-Implant Health and Disease: A Narrative Review
title_fullStr The Oral Microbiome of Peri-Implant Health and Disease: A Narrative Review
title_full_unstemmed The Oral Microbiome of Peri-Implant Health and Disease: A Narrative Review
title_short The Oral Microbiome of Peri-Implant Health and Disease: A Narrative Review
title_sort oral microbiome of peri implant health and disease a narrative review
topic microbiota
peri-implantitis
dental implants
dysbiosis
url https://www.mdpi.com/2304-6767/12/10/299
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