Adaptive attenuation of virulence mediated by Wzc mutation in ST11-KL47 Carbapenem-resistant Klebsiella pneumonia

Adaptive attenuation of virulence mediated by Wzc mutation in ST11-KL47 Carbapenem-resistant Klebsiella pneumonia

IntroductionThe impact of the hypermucoviscosity (HMV) phenotype in ST11-KL47 carbapenem-resistant Klebsiella pneumoniae (CRKp) pathogenicity warrants investigation for public health risk assessment.MethodsWe analyzed 230 clinical ST11-KL47 CRKp to identify the key factor in mucoviscosity acquisitio...

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Main Authors: Yufeng Dai, Qiang Zhao, Huanhuan Yan, Kun Ye, Lifeng Wang, Ling Guo, Na Guo, Wenwen Li, Jiyong Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
CRKP
capsular polysaccharides
hypermucoviscosity
Wzc
virulence
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1561631/full
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