Pharmacokinetics and safety evaluation of anemoside B4 in healthy Beagle dogs

Pharmacokinetics and safety evaluation of anemoside B4 in healthy Beagle dogs

BackgroundAnemoside B4 (AB4), a pentacyclic triterpenoid saponin extracted from the traditional Chinese medicinal herb Pulsatilla chinensis, has shown anti-inflammatory and immunomodulatory effects in both preclinical and clinical studies. However, pharmacokinetic and safety data in dogs remain limi...

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Main Authors:	Jinzhao Ji, Yuqiao Ma, Shaobing Wan, Xiaoqing Ding, Jingyu Wang, Yongcheng Zhong, Yangyang Song, Junqing Zhao, Zhetong Su, Kun Jia, Shoujun Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Veterinary Science
Subjects:	anemoside B4 pharmacokinetics safety dog veterinary medicine
Online Access:	https://www.frontiersin.org/articles/10.3389/fvets.2025.1645372/full
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