Examining Challenges to Co-Design Digital Health Interventions With End Users: Systematic Review
BackgroundDigital health interventions (DHIs) are changing the dynamic of health care by providing personalized, private, and instantaneous solutions to end users. However, the explosion of digital health has been fraught with challenges. The approach to co-design with end us...
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JMIR Publications
2025-03-01
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| Series: | Journal of Medical Internet Research |
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| author | Anthony Duffy Nazanin Boroumandzad Alfredo Lopez Sherman Gregory Christie Indira Riadi Sylvain Moreno |
| author_facet | Anthony Duffy Nazanin Boroumandzad Alfredo Lopez Sherman Gregory Christie Indira Riadi Sylvain Moreno |
| author_sort | Anthony Duffy |
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BackgroundDigital health interventions (DHIs) are changing the dynamic of health care by providing personalized, private, and instantaneous solutions to end users. However, the explosion of digital health has been fraught with challenges. The approach to co-design with end users varies across a diverse domain of stakeholders, often resulting in siloed approaches with no clear consensus. The concept of validating user experiences contrasts greatly between digital stakeholders (ie, user experience and retention) and health stakeholders (ie, safety and efficacy). Several methodologies and frameworks are being implemented to address this challenge to varying degrees of success.
ObjectiveWe aimed to broadly examine the advancements and challenges to co-design DHIs with end users over the last decade. This task was undertaken to identify the key problem areas at the domain level, with the ultimate goal of creating recommendations for better approaches to co-design DHIs with end users.
MethodsWe conducted a systematic search of key databases for co-design studies involving end users in DHIs. Searches were divided into 3 relevant streams: health behavior, user experience, and digital methodologies and frameworks. The eligibility criteria were guided by the PerSPEcTiF framework and the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) checklist. In line with this framework, studies were included in this review that (1) address research on DHIs; (2) focus on interaction and co-design with end users; (3) explain results such that uptake, effectiveness, satisfaction, and health outcomes are discernible, positively or negatively; and (4) describe actionable procedures for better DHI design. The search was conducted in a diverse group of 6 bibliographical databases from January 2015 to May 2024: PsycINFO, PubMed (MEDLINE), Web of Science, CINAHL, Institute of Electrical and Electronics Engineers Xplore, and Scopus. From the 13,961 studies initially screened for titles and abstracts, 489 (3.6%) were eligible for a full-text screening, of which 171 (1.2%) studies matched the inclusion criteria and were included in a qualitative synthesis.
ResultsOf the 171 studies analyzed across 52 journals, we found 5 different research approaches, spanning 8 different digital health solution types and 5 different design methodologies. These studies identified several core themes when co-designing with end users: advancements, which included participatory co-design; challenges, which included participatory co-design, environment and context, testing, and cost and scale; and gaps, which included a pragmatic hybridized framework and industry implementability.
ConclusionsThis research supports a pragmatic shift toward using mixed methods approaches at scale, methods that are primed to take advantage of the emerging big data era of digital health co-design. This organic outlook should blend the vision of digital health co-designers with the pragmatism of Agile design methodology and the rigor of health care metrics.
Trial RegistrationPROSPERO CRD42021238164; https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021238164
International Registered Report Identifier (IRRID)RR2-10.2196/28083 |
| format | Article |
| id | doaj-art-bc8014fdeb634a4eb44637641634a67a |
| institution | DOAJ |
| issn | 1438-8871 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | JMIR Publications |
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| series | Journal of Medical Internet Research |
| spelling | doaj-art-bc8014fdeb634a4eb44637641634a67a2025-08-20T02:52:59ZengJMIR PublicationsJournal of Medical Internet Research1438-88712025-03-0127e5017810.2196/50178Examining Challenges to Co-Design Digital Health Interventions With End Users: Systematic ReviewAnthony Duffyhttps://orcid.org/0000-0002-4769-8819Nazanin Boroumandzadhttps://orcid.org/0009-0006-3683-1238Alfredo Lopez Shermanhttps://orcid.org/0009-0008-4178-5437Gregory Christiehttps://orcid.org/0000-0002-7084-532XIndira Riadihttps://orcid.org/0000-0001-6474-5384Sylvain Morenohttps://orcid.org/0000-0001-6898-7479 BackgroundDigital health interventions (DHIs) are changing the dynamic of health care by providing personalized, private, and instantaneous solutions to end users. However, the explosion of digital health has been fraught with challenges. The approach to co-design with end users varies across a diverse domain of stakeholders, often resulting in siloed approaches with no clear consensus. The concept of validating user experiences contrasts greatly between digital stakeholders (ie, user experience and retention) and health stakeholders (ie, safety and efficacy). Several methodologies and frameworks are being implemented to address this challenge to varying degrees of success. ObjectiveWe aimed to broadly examine the advancements and challenges to co-design DHIs with end users over the last decade. This task was undertaken to identify the key problem areas at the domain level, with the ultimate goal of creating recommendations for better approaches to co-design DHIs with end users. MethodsWe conducted a systematic search of key databases for co-design studies involving end users in DHIs. Searches were divided into 3 relevant streams: health behavior, user experience, and digital methodologies and frameworks. The eligibility criteria were guided by the PerSPEcTiF framework and the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) checklist. In line with this framework, studies were included in this review that (1) address research on DHIs; (2) focus on interaction and co-design with end users; (3) explain results such that uptake, effectiveness, satisfaction, and health outcomes are discernible, positively or negatively; and (4) describe actionable procedures for better DHI design. The search was conducted in a diverse group of 6 bibliographical databases from January 2015 to May 2024: PsycINFO, PubMed (MEDLINE), Web of Science, CINAHL, Institute of Electrical and Electronics Engineers Xplore, and Scopus. From the 13,961 studies initially screened for titles and abstracts, 489 (3.6%) were eligible for a full-text screening, of which 171 (1.2%) studies matched the inclusion criteria and were included in a qualitative synthesis. ResultsOf the 171 studies analyzed across 52 journals, we found 5 different research approaches, spanning 8 different digital health solution types and 5 different design methodologies. These studies identified several core themes when co-designing with end users: advancements, which included participatory co-design; challenges, which included participatory co-design, environment and context, testing, and cost and scale; and gaps, which included a pragmatic hybridized framework and industry implementability. ConclusionsThis research supports a pragmatic shift toward using mixed methods approaches at scale, methods that are primed to take advantage of the emerging big data era of digital health co-design. This organic outlook should blend the vision of digital health co-designers with the pragmatism of Agile design methodology and the rigor of health care metrics. Trial RegistrationPROSPERO CRD42021238164; https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021238164 International Registered Report Identifier (IRRID)RR2-10.2196/28083https://www.jmir.org/2025/1/e50178 |
| spellingShingle | Anthony Duffy Nazanin Boroumandzad Alfredo Lopez Sherman Gregory Christie Indira Riadi Sylvain Moreno Examining Challenges to Co-Design Digital Health Interventions With End Users: Systematic Review Journal of Medical Internet Research |
| title | Examining Challenges to Co-Design Digital Health Interventions With End Users: Systematic Review |
| title_full | Examining Challenges to Co-Design Digital Health Interventions With End Users: Systematic Review |
| title_fullStr | Examining Challenges to Co-Design Digital Health Interventions With End Users: Systematic Review |
| title_full_unstemmed | Examining Challenges to Co-Design Digital Health Interventions With End Users: Systematic Review |
| title_short | Examining Challenges to Co-Design Digital Health Interventions With End Users: Systematic Review |
| title_sort | examining challenges to co design digital health interventions with end users systematic review |
| url | https://www.jmir.org/2025/1/e50178 |
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