Risk factors analysis and prediction model construction of hospital-acquired pneumonia after traumatic brain injury
BackgroundHospital-acquired pneumonia (HBP) is a common and serious infections disease that affects the patients with traumatic brain injury (TBI). Severe pneumonia can lead to high mortality and morbidity in TBI patients. Therefore, it is important to investigate the risk factors and develop a pred...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-07-01
|
| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2025.1518599/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850116866161246208 |
|---|---|
| author | Xiao-Cong Wei Yi-Zi Zhang Min Guo Hai-Bo Tong Yong-Hong Wang Xiao-Qin Wang Hong-Ming Ji Bin Ren Hao Wu |
| author_facet | Xiao-Cong Wei Yi-Zi Zhang Min Guo Hai-Bo Tong Yong-Hong Wang Xiao-Qin Wang Hong-Ming Ji Bin Ren Hao Wu |
| author_sort | Xiao-Cong Wei |
| collection | DOAJ |
| description | BackgroundHospital-acquired pneumonia (HBP) is a common and serious infections disease that affects the patients with traumatic brain injury (TBI). Severe pneumonia can lead to high mortality and morbidity in TBI patients. Therefore, it is important to investigate the risk factors and develop a prediction model for HBP following TBI.MethodsThe clinical data of 285 patients with TBI, admitted to Shanxi Bethune Hospital and Shanxi Provincial People’s Hospital, were collected. Patients were divided into two groups based on the presence or absence of pneumonia. Risk factors for HBP were identified, a predictive model was constructed, and its performance was validated.ResultsSignificant differences were observed between the pneumonia and non-pneumonia groups regarding several factors, including age, history of diabetes, smoking history, white blood cell count, platelet count, albumin levels, Glasgow Coma Scale (GCS) score upon admission, thoracic trauma, craniocerebral surgery, and the need for tracheal intubation post-admission (p < 0.05). Among these, age, smoking history, thoracic trauma, white blood cell count, albumin levels, and admission GCS score were identified as independent risk factors for HBP following TBI. The predictive model based on these six factors demonstrated high accuracy.ConclusionAge, smoking history, thoracic trauma, white blood cell count, albumin levels, and admission GCS score are independent risk factors for HBP after TBI. The predictive model developed based on these factors shows strong predictive accuracy and clinical utility. |
| format | Article |
| id | doaj-art-bc7907e25d40431d9f447cc5aa88c730 |
| institution | OA Journals |
| issn | 1664-2295 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj-art-bc7907e25d40431d9f447cc5aa88c7302025-08-20T02:36:13ZengFrontiers Media S.A.Frontiers in Neurology1664-22952025-07-011610.3389/fneur.2025.15185991518599Risk factors analysis and prediction model construction of hospital-acquired pneumonia after traumatic brain injuryXiao-Cong Wei0Yi-Zi Zhang1Min Guo2Hai-Bo Tong3Yong-Hong Wang4Xiao-Qin Wang5Hong-Ming Ji6Bin Ren7Hao Wu8Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, ChinaShanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, ChinaShanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, ChinaShanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, ChinaShanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, ChinaShanxi Provincial People's Hospital, Taiyuan, ChinaShanxi Provincial People's Hospital, Taiyuan, ChinaShanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, ChinaShanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, ChinaBackgroundHospital-acquired pneumonia (HBP) is a common and serious infections disease that affects the patients with traumatic brain injury (TBI). Severe pneumonia can lead to high mortality and morbidity in TBI patients. Therefore, it is important to investigate the risk factors and develop a prediction model for HBP following TBI.MethodsThe clinical data of 285 patients with TBI, admitted to Shanxi Bethune Hospital and Shanxi Provincial People’s Hospital, were collected. Patients were divided into two groups based on the presence or absence of pneumonia. Risk factors for HBP were identified, a predictive model was constructed, and its performance was validated.ResultsSignificant differences were observed between the pneumonia and non-pneumonia groups regarding several factors, including age, history of diabetes, smoking history, white blood cell count, platelet count, albumin levels, Glasgow Coma Scale (GCS) score upon admission, thoracic trauma, craniocerebral surgery, and the need for tracheal intubation post-admission (p < 0.05). Among these, age, smoking history, thoracic trauma, white blood cell count, albumin levels, and admission GCS score were identified as independent risk factors for HBP following TBI. The predictive model based on these six factors demonstrated high accuracy.ConclusionAge, smoking history, thoracic trauma, white blood cell count, albumin levels, and admission GCS score are independent risk factors for HBP after TBI. The predictive model developed based on these factors shows strong predictive accuracy and clinical utility.https://www.frontiersin.org/articles/10.3389/fneur.2025.1518599/fulltraumatic brain injurypneumoniaprediction modelrisk factors analysishospital-acquired pneumonia (HAP) |
| spellingShingle | Xiao-Cong Wei Yi-Zi Zhang Min Guo Hai-Bo Tong Yong-Hong Wang Xiao-Qin Wang Hong-Ming Ji Bin Ren Hao Wu Risk factors analysis and prediction model construction of hospital-acquired pneumonia after traumatic brain injury Frontiers in Neurology traumatic brain injury pneumonia prediction model risk factors analysis hospital-acquired pneumonia (HAP) |
| title | Risk factors analysis and prediction model construction of hospital-acquired pneumonia after traumatic brain injury |
| title_full | Risk factors analysis and prediction model construction of hospital-acquired pneumonia after traumatic brain injury |
| title_fullStr | Risk factors analysis and prediction model construction of hospital-acquired pneumonia after traumatic brain injury |
| title_full_unstemmed | Risk factors analysis and prediction model construction of hospital-acquired pneumonia after traumatic brain injury |
| title_short | Risk factors analysis and prediction model construction of hospital-acquired pneumonia after traumatic brain injury |
| title_sort | risk factors analysis and prediction model construction of hospital acquired pneumonia after traumatic brain injury |
| topic | traumatic brain injury pneumonia prediction model risk factors analysis hospital-acquired pneumonia (HAP) |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2025.1518599/full |
| work_keys_str_mv | AT xiaocongwei riskfactorsanalysisandpredictionmodelconstructionofhospitalacquiredpneumoniaaftertraumaticbraininjury AT yizizhang riskfactorsanalysisandpredictionmodelconstructionofhospitalacquiredpneumoniaaftertraumaticbraininjury AT minguo riskfactorsanalysisandpredictionmodelconstructionofhospitalacquiredpneumoniaaftertraumaticbraininjury AT haibotong riskfactorsanalysisandpredictionmodelconstructionofhospitalacquiredpneumoniaaftertraumaticbraininjury AT yonghongwang riskfactorsanalysisandpredictionmodelconstructionofhospitalacquiredpneumoniaaftertraumaticbraininjury AT xiaoqinwang riskfactorsanalysisandpredictionmodelconstructionofhospitalacquiredpneumoniaaftertraumaticbraininjury AT hongmingji riskfactorsanalysisandpredictionmodelconstructionofhospitalacquiredpneumoniaaftertraumaticbraininjury AT binren riskfactorsanalysisandpredictionmodelconstructionofhospitalacquiredpneumoniaaftertraumaticbraininjury AT haowu riskfactorsanalysisandpredictionmodelconstructionofhospitalacquiredpneumoniaaftertraumaticbraininjury |