Current advances in solid-phase microextraction technique as a green analytical sample preparation approach

Conventional analytical techniques often rely on harmful chemicals, leading to significant environmental pollution, contamination, and waste generation. Green analytical chemistry aims to develop eco-friendly alternatives, and one of the promising techniques in this field is solid phase microextract...

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Main Authors: Harshika Poojary, Keerthana Selvamuthukumar, Roshna Parveen, Gouri Illanad, Debsmita Mandal, Sophia Koo, Chiranjit Ghosh
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Green Chemistry Letters and Reviews
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Online Access:https://www.tandfonline.com/doi/10.1080/17518253.2025.2486135
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author Harshika Poojary
Keerthana Selvamuthukumar
Roshna Parveen
Gouri Illanad
Debsmita Mandal
Sophia Koo
Chiranjit Ghosh
author_facet Harshika Poojary
Keerthana Selvamuthukumar
Roshna Parveen
Gouri Illanad
Debsmita Mandal
Sophia Koo
Chiranjit Ghosh
author_sort Harshika Poojary
collection DOAJ
description Conventional analytical techniques often rely on harmful chemicals, leading to significant environmental pollution, contamination, and waste generation. Green analytical chemistry aims to develop eco-friendly alternatives, and one of the promising techniques in this field is solid phase microextraction (SPME). As a solvent-free sample preparation method, SPME aligns with the principles of green chemistry by eliminating the need for harmful solvents and minimizing waste production. The versatility of SPME has enabled its effective use in several analytical sample preparation fields including environmental analysis, food analysis, forensic investigation, pharmaceutical analysis, and biomedical research. This technique excels in extracting trace quantities of pharmaceuticals and pesticides from water, soil, and food matrices. In the pharmaceutical and biomedical sectors, SPME is invaluable for drug discovery, enabling the extraction of drugs and metabolites from biological samples. This review explored the diverse applications of SPME across multiple disciplines, offering a comprehensive overview of its uses and advancements. It aims to provide valuable insights for researchers, analysts, and industries seeking sustainable approaches in analytical chemistry, highlighting the potential of SPME for fast, green and efficient practices.
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spelling doaj-art-bc6893dcdfb745658f742fdcc60f238f2025-08-20T03:07:31ZengTaylor & Francis GroupGreen Chemistry Letters and Reviews1751-82531751-71922025-12-0118110.1080/17518253.2025.2486135Current advances in solid-phase microextraction technique as a green analytical sample preparation approachHarshika Poojary0Keerthana Selvamuthukumar1Roshna Parveen2Gouri Illanad3Debsmita Mandal4Sophia Koo5Chiranjit Ghosh6Department of Biotechnology, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, IndiaDepartment of Biotechnology, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, IndiaDepartment of Industrial Biotechnology, Government College of Technology, Coimbatore, IndiaDepartment of Biotechnology, KLE Technological University, Hubballi, IndiaDepartment of Biotechnology, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, IndiaDivision of Infectious Diseases, Brigham and Women’s Hospital, Boston, MA, USADepartment of Biotechnology, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, IndiaConventional analytical techniques often rely on harmful chemicals, leading to significant environmental pollution, contamination, and waste generation. Green analytical chemistry aims to develop eco-friendly alternatives, and one of the promising techniques in this field is solid phase microextraction (SPME). As a solvent-free sample preparation method, SPME aligns with the principles of green chemistry by eliminating the need for harmful solvents and minimizing waste production. The versatility of SPME has enabled its effective use in several analytical sample preparation fields including environmental analysis, food analysis, forensic investigation, pharmaceutical analysis, and biomedical research. This technique excels in extracting trace quantities of pharmaceuticals and pesticides from water, soil, and food matrices. In the pharmaceutical and biomedical sectors, SPME is invaluable for drug discovery, enabling the extraction of drugs and metabolites from biological samples. This review explored the diverse applications of SPME across multiple disciplines, offering a comprehensive overview of its uses and advancements. It aims to provide valuable insights for researchers, analysts, and industries seeking sustainable approaches in analytical chemistry, highlighting the potential of SPME for fast, green and efficient practices.https://www.tandfonline.com/doi/10.1080/17518253.2025.2486135Solid phase microextractionsample preparationmicroextractionheadspace extractionenvironmental researchgreen analytical chemistry
spellingShingle Harshika Poojary
Keerthana Selvamuthukumar
Roshna Parveen
Gouri Illanad
Debsmita Mandal
Sophia Koo
Chiranjit Ghosh
Current advances in solid-phase microextraction technique as a green analytical sample preparation approach
Green Chemistry Letters and Reviews
Solid phase microextraction
sample preparation
microextraction
headspace extraction
environmental research
green analytical chemistry
title Current advances in solid-phase microextraction technique as a green analytical sample preparation approach
title_full Current advances in solid-phase microextraction technique as a green analytical sample preparation approach
title_fullStr Current advances in solid-phase microextraction technique as a green analytical sample preparation approach
title_full_unstemmed Current advances in solid-phase microextraction technique as a green analytical sample preparation approach
title_short Current advances in solid-phase microextraction technique as a green analytical sample preparation approach
title_sort current advances in solid phase microextraction technique as a green analytical sample preparation approach
topic Solid phase microextraction
sample preparation
microextraction
headspace extraction
environmental research
green analytical chemistry
url https://www.tandfonline.com/doi/10.1080/17518253.2025.2486135
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