Psychosocial Trauma History Negatively Impacts Liver Transplant Access in Women with Chronic Liver Disease
Introduction. Few studies have evaluated the impact of psychological trauma (mental, emotional, or physical) on liver transplant (LT) candidacy and outcomes. Methods. We performed a single center retrospective analysis of patients who completed routine LT evaluation between October 2017 and June 202...
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Wiley
2024-01-01
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| Series: | Journal of Transplantation |
| Online Access: | http://dx.doi.org/10.1155/2024/2455942 |
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| author | Katherine M. Cooper Alessandro Colletta Dhruval Amin Darya M. Herscovici Deepika Devuni |
| author_facet | Katherine M. Cooper Alessandro Colletta Dhruval Amin Darya M. Herscovici Deepika Devuni |
| author_sort | Katherine M. Cooper |
| collection | DOAJ |
| description | Introduction. Few studies have evaluated the impact of psychological trauma (mental, emotional, or physical) on liver transplant (LT) candidacy and outcomes. Methods. We performed a single center retrospective analysis of patients who completed routine LT evaluation between October 2017 and June 2021. We identified the prevalence of psychological trauma history in men and women LT candidates and evaluated the association between trauma history and LT access. The primary outcome measure was listing for LT. Results. A total of 463 patients completed LT evaluation, of which 17% (n = 79) reported a history of trauma: 49 of 159 women and 30 of 304 men. Trauma history was significantly more common in women than in men (31% vs. 10%, p<0.001). Women with trauma history were less likely to be listed for LT (80% vs. 93%, p=0.016). Women with trauma history were also more likely to be removed from the LT waitlist (26% vs. 12%, p=0.045); this persists when excluding patients removed for transfer to another center or for medical improvement (22% vs. 7%, p=0.020). In contrast, listing for LT (87% vs. 86%, p=0.973) and waitlist removal (12% vs. 10%, p=0.766) did not differ in men with and without trauma history. In those that received a LT (n = 107), post-LT relapse, rejection, readmissions, and death did not differ in patients with (n=13)and without (n=94) trauma history. Conclusions. Trauma history is associated with reduced access to LT in women but not men with chronic liver disease. Further studies are needed to understand the impact of psychological trauma on LT access and post-LT outcomes. |
| format | Article |
| id | doaj-art-bc682d288f97450fa23e7864e99ee132 |
| institution | Kabale University |
| issn | 2090-0015 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
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| series | Journal of Transplantation |
| spelling | doaj-art-bc682d288f97450fa23e7864e99ee1322025-01-02T22:40:12ZengWileyJournal of Transplantation2090-00152024-01-01202410.1155/2024/2455942Psychosocial Trauma History Negatively Impacts Liver Transplant Access in Women with Chronic Liver DiseaseKatherine M. Cooper0Alessandro Colletta1Dhruval Amin2Darya M. Herscovici3Deepika Devuni4Department of MedicineDepartment of MedicineDepartment of MedicineDepartment of MedicineDepartment of MedicineIntroduction. Few studies have evaluated the impact of psychological trauma (mental, emotional, or physical) on liver transplant (LT) candidacy and outcomes. Methods. We performed a single center retrospective analysis of patients who completed routine LT evaluation between October 2017 and June 2021. We identified the prevalence of psychological trauma history in men and women LT candidates and evaluated the association between trauma history and LT access. The primary outcome measure was listing for LT. Results. A total of 463 patients completed LT evaluation, of which 17% (n = 79) reported a history of trauma: 49 of 159 women and 30 of 304 men. Trauma history was significantly more common in women than in men (31% vs. 10%, p<0.001). Women with trauma history were less likely to be listed for LT (80% vs. 93%, p=0.016). Women with trauma history were also more likely to be removed from the LT waitlist (26% vs. 12%, p=0.045); this persists when excluding patients removed for transfer to another center or for medical improvement (22% vs. 7%, p=0.020). In contrast, listing for LT (87% vs. 86%, p=0.973) and waitlist removal (12% vs. 10%, p=0.766) did not differ in men with and without trauma history. In those that received a LT (n = 107), post-LT relapse, rejection, readmissions, and death did not differ in patients with (n=13)and without (n=94) trauma history. Conclusions. Trauma history is associated with reduced access to LT in women but not men with chronic liver disease. Further studies are needed to understand the impact of psychological trauma on LT access and post-LT outcomes.http://dx.doi.org/10.1155/2024/2455942 |
| spellingShingle | Katherine M. Cooper Alessandro Colletta Dhruval Amin Darya M. Herscovici Deepika Devuni Psychosocial Trauma History Negatively Impacts Liver Transplant Access in Women with Chronic Liver Disease Journal of Transplantation |
| title | Psychosocial Trauma History Negatively Impacts Liver Transplant Access in Women with Chronic Liver Disease |
| title_full | Psychosocial Trauma History Negatively Impacts Liver Transplant Access in Women with Chronic Liver Disease |
| title_fullStr | Psychosocial Trauma History Negatively Impacts Liver Transplant Access in Women with Chronic Liver Disease |
| title_full_unstemmed | Psychosocial Trauma History Negatively Impacts Liver Transplant Access in Women with Chronic Liver Disease |
| title_short | Psychosocial Trauma History Negatively Impacts Liver Transplant Access in Women with Chronic Liver Disease |
| title_sort | psychosocial trauma history negatively impacts liver transplant access in women with chronic liver disease |
| url | http://dx.doi.org/10.1155/2024/2455942 |
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