The Prevalence of Malaria among Children in Ethiopia: A Systematic Review and Meta-Analysis

Background. Malaria is one of the most public health important and life-threatening parasitic infections caused by the protozoan parasite. Since children are immunologically naive to the malaria parasite, they are the main vulnerable groups. During malaria infection, they might have a complication o...

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Main Authors: Yalewayker Tegegne, Abebaw Worede, Adane Derso, Sintayehu Ambachew
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Journal of Parasitology Research
Online Access:http://dx.doi.org/10.1155/2021/6697294
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author Yalewayker Tegegne
Abebaw Worede
Adane Derso
Sintayehu Ambachew
author_facet Yalewayker Tegegne
Abebaw Worede
Adane Derso
Sintayehu Ambachew
author_sort Yalewayker Tegegne
collection DOAJ
description Background. Malaria is one of the most public health important and life-threatening parasitic infections caused by the protozoan parasite. Since children are immunologically naive to the malaria parasite, they are the main vulnerable groups. During malaria infection, they might have a complication of anemia, cerebral malaria, coma, respiratory distress, and a decrease in cognitive and behavioral improvement. Therefore, this review was aimed at determining the pooled prevalence of malaria among children in Ethiopia. Methods. The current systematic review and meta-analysis were conducted based on the guideline of Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement guideline. Electronic bibliographic databases such as Google Scholar, PubMed, and Science Direct were used for searching relevant literature. Besides, the Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instrument (JBI-MAStARI) was used for critical appraisal of studies. Using the STATA 14 software, the pooled Meta logistic regression was computed to present the pooled prevalence with a 95% confidence interval (CI). Result. The overall estimated pooled prevalence of malaria among children in Ethiopia was 9.07 (95% CI: 6.32, 11.82). Subgroup analysis based on malaria signs and symptoms showed that the pooled prevalence of malaria among asymptomatic and symptomatic children was 6.67% (95% CI: 0.36, 12.98) and 27.17% (95% CI: 18.59, 35.76), respectively. Conclusion. The findings revealed a high prevalence of malaria among children in Ethiopia. As a result, still there is a need of improving and rechecking the existing malaria prevention and control measures of the country.
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spelling doaj-art-bc5621c7c2a44b25a40661c22296ebce2025-08-20T03:23:18ZengWileyJournal of Parasitology Research2090-00232090-00312021-01-01202110.1155/2021/66972946697294The Prevalence of Malaria among Children in Ethiopia: A Systematic Review and Meta-AnalysisYalewayker Tegegne0Abebaw Worede1Adane Derso2Sintayehu Ambachew3Department of Medical Parasitology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaDepartment of Clinical Chemistry, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaDepartment of Medical Parasitology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaDepartment of Clinical Chemistry, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaBackground. Malaria is one of the most public health important and life-threatening parasitic infections caused by the protozoan parasite. Since children are immunologically naive to the malaria parasite, they are the main vulnerable groups. During malaria infection, they might have a complication of anemia, cerebral malaria, coma, respiratory distress, and a decrease in cognitive and behavioral improvement. Therefore, this review was aimed at determining the pooled prevalence of malaria among children in Ethiopia. Methods. The current systematic review and meta-analysis were conducted based on the guideline of Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement guideline. Electronic bibliographic databases such as Google Scholar, PubMed, and Science Direct were used for searching relevant literature. Besides, the Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instrument (JBI-MAStARI) was used for critical appraisal of studies. Using the STATA 14 software, the pooled Meta logistic regression was computed to present the pooled prevalence with a 95% confidence interval (CI). Result. The overall estimated pooled prevalence of malaria among children in Ethiopia was 9.07 (95% CI: 6.32, 11.82). Subgroup analysis based on malaria signs and symptoms showed that the pooled prevalence of malaria among asymptomatic and symptomatic children was 6.67% (95% CI: 0.36, 12.98) and 27.17% (95% CI: 18.59, 35.76), respectively. Conclusion. The findings revealed a high prevalence of malaria among children in Ethiopia. As a result, still there is a need of improving and rechecking the existing malaria prevention and control measures of the country.http://dx.doi.org/10.1155/2021/6697294
spellingShingle Yalewayker Tegegne
Abebaw Worede
Adane Derso
Sintayehu Ambachew
The Prevalence of Malaria among Children in Ethiopia: A Systematic Review and Meta-Analysis
Journal of Parasitology Research
title The Prevalence of Malaria among Children in Ethiopia: A Systematic Review and Meta-Analysis
title_full The Prevalence of Malaria among Children in Ethiopia: A Systematic Review and Meta-Analysis
title_fullStr The Prevalence of Malaria among Children in Ethiopia: A Systematic Review and Meta-Analysis
title_full_unstemmed The Prevalence of Malaria among Children in Ethiopia: A Systematic Review and Meta-Analysis
title_short The Prevalence of Malaria among Children in Ethiopia: A Systematic Review and Meta-Analysis
title_sort prevalence of malaria among children in ethiopia a systematic review and meta analysis
url http://dx.doi.org/10.1155/2021/6697294
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