Visual analysis of emerging topics and trends in contrast agent extravasation research in medical imaging: a bibliometric study using CiteSpace and VOSviewer

PurposeThis study presents a visualization of the global research dynamics on contrast agent extravasation in medical imaging using a knowledge map, revealing the research directions, emerging topics, trends, and frontiers in this field.MethodUsing CiteSpace and VOSviewer software with the Web of Sc...

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Main Authors: Yun Liu, Yonghai Dong, Wenfang Zhou, Juhong Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1472637/full
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author Yun Liu
Yonghai Dong
Wenfang Zhou
Juhong Yu
author_facet Yun Liu
Yonghai Dong
Wenfang Zhou
Juhong Yu
author_sort Yun Liu
collection DOAJ
description PurposeThis study presents a visualization of the global research dynamics on contrast agent extravasation in medical imaging using a knowledge map, revealing the research directions, emerging topics, trends, and frontiers in this field.MethodUsing CiteSpace and VOSviewer software with the Web of Science Core Collection database as the data source, a bibliometric analysis was conducted on relevant studies of contrast agent extravasation in medical imaging examinations. Analysis was performed on aspects such as yearly publication volume, country/institution distribution, authorship, co-citation documents, and keywords, leading to the creation of visualizations.ResultsA total of 4,635 articles were included in the study, with the first relevant research report appearing in 1950. The yearly publication and citation volumes have shown an overall increasing trend over the years. Research in this field was predominantly concentrated in the United States, accounting for approximately one-third of the global publication output. The University of California System was the top institution in terms of publication volume. The top five high-frequency keywords were “magnetic resonance imaging,” “computed tomography,” “management,” “diagnosis,” and “contrast agent.” Cluster analysis of keywords revealed three main clusters: “contrast,” “fluorescein angiography,” and “focused ultrasound,” showing good continuity over time. The keyword burst analysis identified that “gd dtpa” had the highest burst value of 20.51. The emergence of keywords shifted over time. At present, the keywords that are still emerging are “multimodal imaging,” “case report,” and “leakage.”ConclusionMore scholars are dedicating efforts to research on contrast agent extravasation in medical imaging. “Multimodal imaging” will be a key research focus in the foreseeable future. Contrast agent extravasation remains a substantial challenge with high research value in medical imaging.
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spelling doaj-art-bc4e6accf72e4227902169892404d0f52025-08-20T02:43:49ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-02-011210.3389/fmed.2025.14726371472637Visual analysis of emerging topics and trends in contrast agent extravasation research in medical imaging: a bibliometric study using CiteSpace and VOSviewerYun Liu0Yonghai Dong1Wenfang Zhou2Juhong Yu3Department of Imaging, Jiangxi Provincial People’s Hospital (The First Affiliated Hospital of Nanchang Medical College), Nanchang, ChinaYoung Scientific Research and Innovation Team, Jiangxi Provincial Center for Disease Control and Prevention, Nanchang, ChinaYoung Scientific Research and Innovation Team, Jiangxi Provincial Center for Disease Control and Prevention, Nanchang, ChinaDepartment of Imaging, Jiangxi Provincial People’s Hospital (The First Affiliated Hospital of Nanchang Medical College), Nanchang, ChinaPurposeThis study presents a visualization of the global research dynamics on contrast agent extravasation in medical imaging using a knowledge map, revealing the research directions, emerging topics, trends, and frontiers in this field.MethodUsing CiteSpace and VOSviewer software with the Web of Science Core Collection database as the data source, a bibliometric analysis was conducted on relevant studies of contrast agent extravasation in medical imaging examinations. Analysis was performed on aspects such as yearly publication volume, country/institution distribution, authorship, co-citation documents, and keywords, leading to the creation of visualizations.ResultsA total of 4,635 articles were included in the study, with the first relevant research report appearing in 1950. The yearly publication and citation volumes have shown an overall increasing trend over the years. Research in this field was predominantly concentrated in the United States, accounting for approximately one-third of the global publication output. The University of California System was the top institution in terms of publication volume. The top five high-frequency keywords were “magnetic resonance imaging,” “computed tomography,” “management,” “diagnosis,” and “contrast agent.” Cluster analysis of keywords revealed three main clusters: “contrast,” “fluorescein angiography,” and “focused ultrasound,” showing good continuity over time. The keyword burst analysis identified that “gd dtpa” had the highest burst value of 20.51. The emergence of keywords shifted over time. At present, the keywords that are still emerging are “multimodal imaging,” “case report,” and “leakage.”ConclusionMore scholars are dedicating efforts to research on contrast agent extravasation in medical imaging. “Multimodal imaging” will be a key research focus in the foreseeable future. Contrast agent extravasation remains a substantial challenge with high research value in medical imaging.https://www.frontiersin.org/articles/10.3389/fmed.2025.1472637/fullcontrast agentextravasationimagingvisual analysisCiteSpaceVOSviewer
spellingShingle Yun Liu
Yonghai Dong
Wenfang Zhou
Juhong Yu
Visual analysis of emerging topics and trends in contrast agent extravasation research in medical imaging: a bibliometric study using CiteSpace and VOSviewer
Frontiers in Medicine
contrast agent
extravasation
imaging
visual analysis
CiteSpace
VOSviewer
title Visual analysis of emerging topics and trends in contrast agent extravasation research in medical imaging: a bibliometric study using CiteSpace and VOSviewer
title_full Visual analysis of emerging topics and trends in contrast agent extravasation research in medical imaging: a bibliometric study using CiteSpace and VOSviewer
title_fullStr Visual analysis of emerging topics and trends in contrast agent extravasation research in medical imaging: a bibliometric study using CiteSpace and VOSviewer
title_full_unstemmed Visual analysis of emerging topics and trends in contrast agent extravasation research in medical imaging: a bibliometric study using CiteSpace and VOSviewer
title_short Visual analysis of emerging topics and trends in contrast agent extravasation research in medical imaging: a bibliometric study using CiteSpace and VOSviewer
title_sort visual analysis of emerging topics and trends in contrast agent extravasation research in medical imaging a bibliometric study using citespace and vosviewer
topic contrast agent
extravasation
imaging
visual analysis
CiteSpace
VOSviewer
url https://www.frontiersin.org/articles/10.3389/fmed.2025.1472637/full
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