Clinical Analysis of 42 Cases of Ocular Ischemic Syndrome

Ocular ischemic syndrome (OIS) is a severe ocular disease caused by ocular hypoperfusion due to stenosis or occlusion of the common or internal carotid arteries. OIS is easily misdiagnosed or undiagnosed given its asymptomatic onset and complicated ocular manifestations. The present study reviewed 4...

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Main Authors: Jingyi Luo, Zhichao Yan, Yu Jia, Rongjiang Luo
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2018/2606147
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author Jingyi Luo
Zhichao Yan
Yu Jia
Rongjiang Luo
author_facet Jingyi Luo
Zhichao Yan
Yu Jia
Rongjiang Luo
author_sort Jingyi Luo
collection DOAJ
description Ocular ischemic syndrome (OIS) is a severe ocular disease caused by ocular hypoperfusion due to stenosis or occlusion of the common or internal carotid arteries. OIS is easily misdiagnosed or undiagnosed given its asymptomatic onset and complicated ocular manifestations. The present study reviewed 42 patients with OIS, including 30 males (71.43%), 29 older patients (69.05%, >61 yrs), and 35 patients (83.33%) with two or more systemic diseases. Only 6 patients had ocular symptoms as the initial signs upon visiting the Department of Ophthalmology of three hospitals (the First Affiliated Hospital, Sun Yat-sen University; Zhongshan Ophthalmic Center, Sun Yat-sen University; and the Second Affiliated Hospital, Guangzhou Medical University). The ocular symptoms varied from visual deterioration to periorbital pain. Thirty-seven patients (88.10%) complained of constitutional symptoms. Ocular manifestations were diverse and involved both anterior and posterior segments. We reported a case of corneal edema and corneal epithelium erosion in the ipsilateral eye due to internal carotid artery stenosis. As the clinical manifestations of OIS are complex, ophthalmologists must carefully examine patients to avoid a misdiagnosis or a failure to diagnose. The management of OIS requires cooperation with cardiologists and neurologists.
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spelling doaj-art-bc4b422481b1415785a316a683e2c0952025-02-03T05:46:51ZengWileyJournal of Ophthalmology2090-004X2090-00582018-01-01201810.1155/2018/26061472606147Clinical Analysis of 42 Cases of Ocular Ischemic SyndromeJingyi Luo0Zhichao Yan1Yu Jia2Rongjiang Luo3Department of Ophthalmology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, ChinaDepartment of Ophthalmology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, ChinaOcular ischemic syndrome (OIS) is a severe ocular disease caused by ocular hypoperfusion due to stenosis or occlusion of the common or internal carotid arteries. OIS is easily misdiagnosed or undiagnosed given its asymptomatic onset and complicated ocular manifestations. The present study reviewed 42 patients with OIS, including 30 males (71.43%), 29 older patients (69.05%, >61 yrs), and 35 patients (83.33%) with two or more systemic diseases. Only 6 patients had ocular symptoms as the initial signs upon visiting the Department of Ophthalmology of three hospitals (the First Affiliated Hospital, Sun Yat-sen University; Zhongshan Ophthalmic Center, Sun Yat-sen University; and the Second Affiliated Hospital, Guangzhou Medical University). The ocular symptoms varied from visual deterioration to periorbital pain. Thirty-seven patients (88.10%) complained of constitutional symptoms. Ocular manifestations were diverse and involved both anterior and posterior segments. We reported a case of corneal edema and corneal epithelium erosion in the ipsilateral eye due to internal carotid artery stenosis. As the clinical manifestations of OIS are complex, ophthalmologists must carefully examine patients to avoid a misdiagnosis or a failure to diagnose. The management of OIS requires cooperation with cardiologists and neurologists.http://dx.doi.org/10.1155/2018/2606147
spellingShingle Jingyi Luo
Zhichao Yan
Yu Jia
Rongjiang Luo
Clinical Analysis of 42 Cases of Ocular Ischemic Syndrome
Journal of Ophthalmology
title Clinical Analysis of 42 Cases of Ocular Ischemic Syndrome
title_full Clinical Analysis of 42 Cases of Ocular Ischemic Syndrome
title_fullStr Clinical Analysis of 42 Cases of Ocular Ischemic Syndrome
title_full_unstemmed Clinical Analysis of 42 Cases of Ocular Ischemic Syndrome
title_short Clinical Analysis of 42 Cases of Ocular Ischemic Syndrome
title_sort clinical analysis of 42 cases of ocular ischemic syndrome
url http://dx.doi.org/10.1155/2018/2606147
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