Assessment of Left Ventricular Structural Remodelling in Patients with Diabetic Cardiomyopathy by Cardiovascular Magnetic Resonance
Background. Diabetic cardiomyopathy (DCM) is always accompanied with alteration of left ventricular structure and function. The aims of this study were to assess the structural remodelling in patients with DCM by cardiovascular magnetic resonance (CMR) and correlation of structural remodelling with...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2016/4786925 |
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| _version_ | 1850178445184598016 |
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| author | Yongning Shang Xiaochun Zhang Liu Chen Weiling Leng Xiaotian Lei Qi Yang Ziwen Liang Jian Wang |
| author_facet | Yongning Shang Xiaochun Zhang Liu Chen Weiling Leng Xiaotian Lei Qi Yang Ziwen Liang Jian Wang |
| author_sort | Yongning Shang |
| collection | DOAJ |
| description | Background. Diabetic cardiomyopathy (DCM) is always accompanied with alteration of left ventricular structure and function. The aims of this study were to assess the structural remodelling in patients with DCM by cardiovascular magnetic resonance (CMR) and correlation of structural remodelling with severity of DCM. Methods. Twenty-five patients (53.8±8.8 years, 52.0% males) with DCM and thirty-one normal healthy controls (51.9±13.6 years, 45.2% males) were scanned by CMR cine to assess function and structure of left ventricular. Length of diabetic history and results of cardiac echocardiography (E′, A′, and E′/A′) were also measured. Results. Compared with normal controls group, DCM group was associated with significantly increased ratio of left ventricular mass at end diastole to end-diastolic volume (MVR) (P<0.05) and no significant difference was in mass at end diastole (P>0.05). The ratio correlated with both length of diabetic history and echocardiographic Doppler tissue imaging E′ (all P<0.05). Conclusions. CMR can be a powerful technique to assess LV remodelling, and MVR may be considered as an imaging marker to evaluate the severity of LV remodelling in patients with DCM. |
| format | Article |
| id | doaj-art-bc472b4af43b4f2ca2654c243a400edd |
| institution | OA Journals |
| issn | 2314-6745 2314-6753 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-bc472b4af43b4f2ca2654c243a400edd2025-08-20T02:18:43ZengWileyJournal of Diabetes Research2314-67452314-67532016-01-01201610.1155/2016/47869254786925Assessment of Left Ventricular Structural Remodelling in Patients with Diabetic Cardiomyopathy by Cardiovascular Magnetic ResonanceYongning Shang0Xiaochun Zhang1Liu Chen2Weiling Leng3Xiaotian Lei4Qi Yang5Ziwen Liang6Jian Wang7Department of Radiology, Southwest Hospital, Third Military Medical University, Chongqing 400038, ChinaDepartment of Radiology, Southwest Hospital, Third Military Medical University, Chongqing 400038, ChinaDepartment of Endocrinology, Southwest Hospital, Third Military Medical University, Chongqing 400038, ChinaDepartment of Endocrinology, Southwest Hospital, Third Military Medical University, Chongqing 400038, ChinaDepartment of Endocrinology, Southwest Hospital, Third Military Medical University, Chongqing 400038, ChinaDepartment of Radiology, Xuanwu Hospital, Beijing 100053, ChinaDepartment of Endocrinology, Southwest Hospital, Third Military Medical University, Chongqing 400038, ChinaDepartment of Radiology, Southwest Hospital, Third Military Medical University, Chongqing 400038, ChinaBackground. Diabetic cardiomyopathy (DCM) is always accompanied with alteration of left ventricular structure and function. The aims of this study were to assess the structural remodelling in patients with DCM by cardiovascular magnetic resonance (CMR) and correlation of structural remodelling with severity of DCM. Methods. Twenty-five patients (53.8±8.8 years, 52.0% males) with DCM and thirty-one normal healthy controls (51.9±13.6 years, 45.2% males) were scanned by CMR cine to assess function and structure of left ventricular. Length of diabetic history and results of cardiac echocardiography (E′, A′, and E′/A′) were also measured. Results. Compared with normal controls group, DCM group was associated with significantly increased ratio of left ventricular mass at end diastole to end-diastolic volume (MVR) (P<0.05) and no significant difference was in mass at end diastole (P>0.05). The ratio correlated with both length of diabetic history and echocardiographic Doppler tissue imaging E′ (all P<0.05). Conclusions. CMR can be a powerful technique to assess LV remodelling, and MVR may be considered as an imaging marker to evaluate the severity of LV remodelling in patients with DCM.http://dx.doi.org/10.1155/2016/4786925 |
| spellingShingle | Yongning Shang Xiaochun Zhang Liu Chen Weiling Leng Xiaotian Lei Qi Yang Ziwen Liang Jian Wang Assessment of Left Ventricular Structural Remodelling in Patients with Diabetic Cardiomyopathy by Cardiovascular Magnetic Resonance Journal of Diabetes Research |
| title | Assessment of Left Ventricular Structural Remodelling in Patients with Diabetic Cardiomyopathy by Cardiovascular Magnetic Resonance |
| title_full | Assessment of Left Ventricular Structural Remodelling in Patients with Diabetic Cardiomyopathy by Cardiovascular Magnetic Resonance |
| title_fullStr | Assessment of Left Ventricular Structural Remodelling in Patients with Diabetic Cardiomyopathy by Cardiovascular Magnetic Resonance |
| title_full_unstemmed | Assessment of Left Ventricular Structural Remodelling in Patients with Diabetic Cardiomyopathy by Cardiovascular Magnetic Resonance |
| title_short | Assessment of Left Ventricular Structural Remodelling in Patients with Diabetic Cardiomyopathy by Cardiovascular Magnetic Resonance |
| title_sort | assessment of left ventricular structural remodelling in patients with diabetic cardiomyopathy by cardiovascular magnetic resonance |
| url | http://dx.doi.org/10.1155/2016/4786925 |
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