The Effect of Parkinson’s Disease on Patients Undergoing Lumbar Spine Surgery

Study Design. Retrospective Database Analysis. Objective. The purpose of this study was to assess characteristics and outcomes of patients with Parkinson’s disease (PD) undergoing lumbar spine surgery for degenerative conditions. Methods. The Nationwide Inpatient Sample was examined from 2002 to 201...

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Main Authors: Jeremy Steinberger, Jeffrey Gilligan, Branko Skovrlj, Christopher A. Sarkiss, Javier Z. Guzman, Samuel K. Cho, John M. Caridi
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.1155/2018/8428403
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author Jeremy Steinberger
Jeffrey Gilligan
Branko Skovrlj
Christopher A. Sarkiss
Javier Z. Guzman
Samuel K. Cho
John M. Caridi
author_facet Jeremy Steinberger
Jeffrey Gilligan
Branko Skovrlj
Christopher A. Sarkiss
Javier Z. Guzman
Samuel K. Cho
John M. Caridi
author_sort Jeremy Steinberger
collection DOAJ
description Study Design. Retrospective Database Analysis. Objective. The purpose of this study was to assess characteristics and outcomes of patients with Parkinson’s disease (PD) undergoing lumbar spine surgery for degenerative conditions. Methods. The Nationwide Inpatient Sample was examined from 2002 to 2011. Patients were included for study based on ICD-9-CM procedural codes for lumbar spine surgery and substratified to degenerative diagnoses. Incidence and baseline patient characteristics were determined. Multivariable analysis was performed to determine independent risk factors increasing incidence of lumbar fusion revision in PD patients. Results. PD patients account for 0.9% of all degenerative lumbar procedures. At baseline, PD patients are older (70.7 versus 58.9, p<0.0001) and more likely to be male (58.6% male, p<160.0001). Mean length of stay (LOS) was increased in PD patients undergoing lumbar fusion (5.1 days versus 4.0 days, p<0.0001) and lumbar fusion revision (6.2 days versus 4.8 days, p<180.0001). Costs were 7.9% (p<0.0001) higher for lumbar fusion and 25.2% (p<0.0001) higher for lumbar fusion revision in PD patients. Multivariable analysis indicates that osteoporosis, fluid/electrolyte disorders, blood loss anemia, and insurance status are significant independent predictors of lumbar fusion revision in patients with PD. Conclusion. PD patients undergoing lumbar surgery for degenerative conditions have increased LOS and costs when compared to patients without PD.
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spelling doaj-art-bc457f5f31fc4e31ade76583e51849352025-08-20T02:18:43ZengWileyParkinson's Disease2090-80832042-00802018-01-01201810.1155/2018/84284038428403The Effect of Parkinson’s Disease on Patients Undergoing Lumbar Spine SurgeryJeremy Steinberger0Jeffrey Gilligan1Branko Skovrlj2Christopher A. Sarkiss3Javier Z. Guzman4Samuel K. Cho5John M. Caridi6Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, USADepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, USADepartment of Neurosurgery, North Jersey Spine Group, Wayne, NJ, USADepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, USADepartment of Orthopaedics, Icahn School of Medicine at Mount Sinai, New York, NY, USADepartment of Orthopaedics, Icahn School of Medicine at Mount Sinai, New York, NY, USADepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, USAStudy Design. Retrospective Database Analysis. Objective. The purpose of this study was to assess characteristics and outcomes of patients with Parkinson’s disease (PD) undergoing lumbar spine surgery for degenerative conditions. Methods. The Nationwide Inpatient Sample was examined from 2002 to 2011. Patients were included for study based on ICD-9-CM procedural codes for lumbar spine surgery and substratified to degenerative diagnoses. Incidence and baseline patient characteristics were determined. Multivariable analysis was performed to determine independent risk factors increasing incidence of lumbar fusion revision in PD patients. Results. PD patients account for 0.9% of all degenerative lumbar procedures. At baseline, PD patients are older (70.7 versus 58.9, p<0.0001) and more likely to be male (58.6% male, p<160.0001). Mean length of stay (LOS) was increased in PD patients undergoing lumbar fusion (5.1 days versus 4.0 days, p<0.0001) and lumbar fusion revision (6.2 days versus 4.8 days, p<180.0001). Costs were 7.9% (p<0.0001) higher for lumbar fusion and 25.2% (p<0.0001) higher for lumbar fusion revision in PD patients. Multivariable analysis indicates that osteoporosis, fluid/electrolyte disorders, blood loss anemia, and insurance status are significant independent predictors of lumbar fusion revision in patients with PD. Conclusion. PD patients undergoing lumbar surgery for degenerative conditions have increased LOS and costs when compared to patients without PD.http://dx.doi.org/10.1155/2018/8428403
spellingShingle Jeremy Steinberger
Jeffrey Gilligan
Branko Skovrlj
Christopher A. Sarkiss
Javier Z. Guzman
Samuel K. Cho
John M. Caridi
The Effect of Parkinson’s Disease on Patients Undergoing Lumbar Spine Surgery
Parkinson's Disease
title The Effect of Parkinson’s Disease on Patients Undergoing Lumbar Spine Surgery
title_full The Effect of Parkinson’s Disease on Patients Undergoing Lumbar Spine Surgery
title_fullStr The Effect of Parkinson’s Disease on Patients Undergoing Lumbar Spine Surgery
title_full_unstemmed The Effect of Parkinson’s Disease on Patients Undergoing Lumbar Spine Surgery
title_short The Effect of Parkinson’s Disease on Patients Undergoing Lumbar Spine Surgery
title_sort effect of parkinson s disease on patients undergoing lumbar spine surgery
url http://dx.doi.org/10.1155/2018/8428403
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