SUCCESSFUL USE OF ETANERCEPT IN A PATIENT WITH POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS WITH AN OVERVIEW OF THE PREDICTORS OF A GOOD RESPONSE TO ONGOING THERAPY
The article presents a case of polyarticular juvenile idiopathic arthritis resistant to methotrexate therapy and nonsteroidal antiinflammatory drugs. The child was prescribed a tumor necrosis factor inhibitor etanercept at a dose of 0.4 mg/kg body weight2 times/week. The treatm...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
"Paediatrician" Publishers LLC
2017-09-01
|
| Series: | Вопросы современной педиатрии |
| Subjects: | |
| Online Access: | https://vsp.spr-journal.ru/jour/article/view/1791 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849411734956146688 |
|---|---|
| author | Anna V. Karaseva Ekaterina I. Alexeeva Tatyana M. Dvoryakovskaya |
| author_facet | Anna V. Karaseva Ekaterina I. Alexeeva Tatyana M. Dvoryakovskaya |
| author_sort | Anna V. Karaseva |
| collection | DOAJ |
| description | The article presents a case of polyarticular juvenile idiopathic arthritis resistant to methotrexate therapy and nonsteroidal antiinflammatory drugs. The child was prescribed a tumor necrosis factor inhibitor etanercept at a dose of 0.4 mg/kg body weight2 times/week. The treatment with etanercept induced remission of the disease, ensured the function restoration in the joints. The predictors of a good response to etanercept were the younger age, the short course of the disease, the use of a small number of immunosuppressants before prescription of etanercept, the absence of concomitant use of glucocorticosteroids, and the absence of uveitis. |
| format | Article |
| id | doaj-art-bc3d972fbf674b66920c3c7155ecbc67 |
| institution | Kabale University |
| issn | 1682-5527 1682-5535 |
| language | English |
| publishDate | 2017-09-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj-art-bc3d972fbf674b66920c3c7155ecbc672025-08-20T03:34:41Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352017-09-0116432132510.15690/vsp.v16i4.17791697SUCCESSFUL USE OF ETANERCEPT IN A PATIENT WITH POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS WITH AN OVERVIEW OF THE PREDICTORS OF A GOOD RESPONSE TO ONGOING THERAPYAnna V. Karaseva0Ekaterina I. Alexeeva1Tatyana M. Dvoryakovskaya2National Medical Research Center of Children’s HealthNational Medical Research Center of Children’s Health; Sechenov First Moscow State Medical UniversityNational Medical Research Center of Children’s Health; Sechenov First Moscow State Medical UniversityThe article presents a case of polyarticular juvenile idiopathic arthritis resistant to methotrexate therapy and nonsteroidal antiinflammatory drugs. The child was prescribed a tumor necrosis factor inhibitor etanercept at a dose of 0.4 mg/kg body weight2 times/week. The treatment with etanercept induced remission of the disease, ensured the function restoration in the joints. The predictors of a good response to etanercept were the younger age, the short course of the disease, the use of a small number of immunosuppressants before prescription of etanercept, the absence of concomitant use of glucocorticosteroids, and the absence of uveitis.https://vsp.spr-journal.ru/jour/article/view/1791childrenjuvenile idiopathic arthritistherapyetanerceptresponse predictors |
| spellingShingle | Anna V. Karaseva Ekaterina I. Alexeeva Tatyana M. Dvoryakovskaya SUCCESSFUL USE OF ETANERCEPT IN A PATIENT WITH POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS WITH AN OVERVIEW OF THE PREDICTORS OF A GOOD RESPONSE TO ONGOING THERAPY Вопросы современной педиатрии children juvenile idiopathic arthritis therapy etanercept response predictors |
| title | SUCCESSFUL USE OF ETANERCEPT IN A PATIENT WITH POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS WITH AN OVERVIEW OF THE PREDICTORS OF A GOOD RESPONSE TO ONGOING THERAPY |
| title_full | SUCCESSFUL USE OF ETANERCEPT IN A PATIENT WITH POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS WITH AN OVERVIEW OF THE PREDICTORS OF A GOOD RESPONSE TO ONGOING THERAPY |
| title_fullStr | SUCCESSFUL USE OF ETANERCEPT IN A PATIENT WITH POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS WITH AN OVERVIEW OF THE PREDICTORS OF A GOOD RESPONSE TO ONGOING THERAPY |
| title_full_unstemmed | SUCCESSFUL USE OF ETANERCEPT IN A PATIENT WITH POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS WITH AN OVERVIEW OF THE PREDICTORS OF A GOOD RESPONSE TO ONGOING THERAPY |
| title_short | SUCCESSFUL USE OF ETANERCEPT IN A PATIENT WITH POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS WITH AN OVERVIEW OF THE PREDICTORS OF A GOOD RESPONSE TO ONGOING THERAPY |
| title_sort | successful use of etanercept in a patient with polyarticular juvenile idiopathic arthritis with an overview of the predictors of a good response to ongoing therapy |
| topic | children juvenile idiopathic arthritis therapy etanercept response predictors |
| url | https://vsp.spr-journal.ru/jour/article/view/1791 |
| work_keys_str_mv | AT annavkaraseva successfuluseofetanerceptinapatientwithpolyarticularjuvenileidiopathicarthritiswithanoverviewofthepredictorsofagoodresponsetoongoingtherapy AT ekaterinaialexeeva successfuluseofetanerceptinapatientwithpolyarticularjuvenileidiopathicarthritiswithanoverviewofthepredictorsofagoodresponsetoongoingtherapy AT tatyanamdvoryakovskaya successfuluseofetanerceptinapatientwithpolyarticularjuvenileidiopathicarthritiswithanoverviewofthepredictorsofagoodresponsetoongoingtherapy |