The delivery carriers and applications for Xiaobojian
Abstract Berberine, also known as Xiaobojian (XBJ), is a quaternary ammonium alkaloid isolated from the traditional Chinese medicine Coptis chinensis, and is the main effective ingredient for antibacterial purpose. This work systematically reviewed recent researches on XBJ in the whole range of deli...
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| Format: | Article |
| Language: | English |
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Springer
2025-03-01
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| Series: | Discover Nano |
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| Online Access: | https://doi.org/10.1186/s11671-025-04239-1 |
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| author | Shiyu Huang Gangliang Huang |
| author_facet | Shiyu Huang Gangliang Huang |
| author_sort | Shiyu Huang |
| collection | DOAJ |
| description | Abstract Berberine, also known as Xiaobojian (XBJ), is a quaternary ammonium alkaloid isolated from the traditional Chinese medicine Coptis chinensis, and is the main effective ingredient for antibacterial purpose. This work systematically reviewed recent researches on XBJ in the whole range of delivery technologies. Compared with XBJ monomer administration, other forms of drug administration, such as tablets, pellets, XBJ polymer delivery system, lipid delivery system, superdeformed vesicles nanocrystallization or emulsification of XBJ and some special substances, will increase the absorption of XBJ. XBJ can be administered through various carriers, including oral administration and topical application. The importance of XBJ carrier administration is mainly reflected in wide application prospects, various pharmacological effects, and improving drug efficacy. Graphical Abstract |
| format | Article |
| id | doaj-art-bc3a856eeef64472b5bd6a30063dbef4 |
| institution | OA Journals |
| issn | 2731-9229 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Springer |
| record_format | Article |
| series | Discover Nano |
| spelling | doaj-art-bc3a856eeef64472b5bd6a30063dbef42025-08-20T02:10:20ZengSpringerDiscover Nano2731-92292025-03-0120111310.1186/s11671-025-04239-1The delivery carriers and applications for XiaobojianShiyu Huang0Gangliang Huang1Key Laboratory of Carbohydrate Science and Engineering, Chongqing Key Laboratory of Inorganic Functional Materials, Chongqing Normal UniversityKey Laboratory of Carbohydrate Science and Engineering, Chongqing Key Laboratory of Inorganic Functional Materials, Chongqing Normal UniversityAbstract Berberine, also known as Xiaobojian (XBJ), is a quaternary ammonium alkaloid isolated from the traditional Chinese medicine Coptis chinensis, and is the main effective ingredient for antibacterial purpose. This work systematically reviewed recent researches on XBJ in the whole range of delivery technologies. Compared with XBJ monomer administration, other forms of drug administration, such as tablets, pellets, XBJ polymer delivery system, lipid delivery system, superdeformed vesicles nanocrystallization or emulsification of XBJ and some special substances, will increase the absorption of XBJ. XBJ can be administered through various carriers, including oral administration and topical application. The importance of XBJ carrier administration is mainly reflected in wide application prospects, various pharmacological effects, and improving drug efficacy. Graphical Abstracthttps://doi.org/10.1186/s11671-025-04239-1Delivery carriersCharacteristicsApplicationsXBJs |
| spellingShingle | Shiyu Huang Gangliang Huang The delivery carriers and applications for Xiaobojian Discover Nano Delivery carriers Characteristics Applications XBJs |
| title | The delivery carriers and applications for Xiaobojian |
| title_full | The delivery carriers and applications for Xiaobojian |
| title_fullStr | The delivery carriers and applications for Xiaobojian |
| title_full_unstemmed | The delivery carriers and applications for Xiaobojian |
| title_short | The delivery carriers and applications for Xiaobojian |
| title_sort | delivery carriers and applications for xiaobojian |
| topic | Delivery carriers Characteristics Applications XBJs |
| url | https://doi.org/10.1186/s11671-025-04239-1 |
| work_keys_str_mv | AT shiyuhuang thedeliverycarriersandapplicationsforxiaobojian AT ganglianghuang thedeliverycarriersandapplicationsforxiaobojian AT shiyuhuang deliverycarriersandapplicationsforxiaobojian AT ganglianghuang deliverycarriersandapplicationsforxiaobojian |