Acromegaly, Herniation of Cerebellar Tonsils, and Arnold–Chiari 1 Malformation: The Importance of Right Definitions
We present a case of acromegaly associated with Arnold–Chiari 1 malformation and a literature review regarding this association, mainly focusing on the importance of a clear distinction between Chiari malformation and herniation of cerebellar tonsils (CTH). Indeed, in many clinical cases, this disti...
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2024/4733399 |
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| author | Alessandro Ciarloni Gianmaria Salvio |
| author_facet | Alessandro Ciarloni Gianmaria Salvio |
| author_sort | Alessandro Ciarloni |
| collection | DOAJ |
| description | We present a case of acromegaly associated with Arnold–Chiari 1 malformation and a literature review regarding this association, mainly focusing on the importance of a clear distinction between Chiari malformation and herniation of cerebellar tonsils (CTH). Indeed, in many clinical cases, this distinction has not been properly made and a better description of the radiological findings could be important for the clinical management of these patients. In fact, Arnold–Chiari 1 malformation, as a congenital disease, is not caused by acquired growth hormone (GH) excess, but the latter could worsen pre-existing CTH or even induce it ex novo. Therefore, awareness of this condition in the clinical management of acromegaly appears crucial. |
| format | Article |
| id | doaj-art-bc30ea93a4cf4fedb91c3d8d20255f59 |
| institution | Kabale University |
| issn | 2090-651X |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-bc30ea93a4cf4fedb91c3d8d20255f592025-02-03T05:55:20ZengWileyCase Reports in Endocrinology2090-651X2024-01-01202410.1155/2024/4733399Acromegaly, Herniation of Cerebellar Tonsils, and Arnold–Chiari 1 Malformation: The Importance of Right DefinitionsAlessandro Ciarloni0Gianmaria Salvio1Endocrinology ClinicEndocrinology ClinicWe present a case of acromegaly associated with Arnold–Chiari 1 malformation and a literature review regarding this association, mainly focusing on the importance of a clear distinction between Chiari malformation and herniation of cerebellar tonsils (CTH). Indeed, in many clinical cases, this distinction has not been properly made and a better description of the radiological findings could be important for the clinical management of these patients. In fact, Arnold–Chiari 1 malformation, as a congenital disease, is not caused by acquired growth hormone (GH) excess, but the latter could worsen pre-existing CTH or even induce it ex novo. Therefore, awareness of this condition in the clinical management of acromegaly appears crucial.http://dx.doi.org/10.1155/2024/4733399 |
| spellingShingle | Alessandro Ciarloni Gianmaria Salvio Acromegaly, Herniation of Cerebellar Tonsils, and Arnold–Chiari 1 Malformation: The Importance of Right Definitions Case Reports in Endocrinology |
| title | Acromegaly, Herniation of Cerebellar Tonsils, and Arnold–Chiari 1 Malformation: The Importance of Right Definitions |
| title_full | Acromegaly, Herniation of Cerebellar Tonsils, and Arnold–Chiari 1 Malformation: The Importance of Right Definitions |
| title_fullStr | Acromegaly, Herniation of Cerebellar Tonsils, and Arnold–Chiari 1 Malformation: The Importance of Right Definitions |
| title_full_unstemmed | Acromegaly, Herniation of Cerebellar Tonsils, and Arnold–Chiari 1 Malformation: The Importance of Right Definitions |
| title_short | Acromegaly, Herniation of Cerebellar Tonsils, and Arnold–Chiari 1 Malformation: The Importance of Right Definitions |
| title_sort | acromegaly herniation of cerebellar tonsils and arnold chiari 1 malformation the importance of right definitions |
| url | http://dx.doi.org/10.1155/2024/4733399 |
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