Suspected glaucoma and early stage glaucoma: differential diagnostic criteria
Purpose: to set out morphofunctional differences in the ophthalmic status between suspected glaucoma (SG) and the initial stage of primary open angle glaucoma (POAG), determine the values of interocular asymmetry of the analyzed parameters of fellow eyes and create a model able to distinguish, with...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Real Time Ltd
2018-10-01
|
| Series: | Российский офтальмологический журнал |
| Subjects: | |
| Online Access: | https://roj.igb.ru/jour/article/view/117 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850047663557312512 |
|---|---|
| author | R. V. Avdeev A. S. Alexandrov M. U. Arapiev N. A. Bakunina A. S. Basinskiy D. A. Belaya A. Y. Brezhnev N. V. Volkova L. M. Gabdrakhmanov I. R. Gazizova A. B. Galimova V. V. Garkavenko A. M. Getmanova V. V. Gorodnichiy A. A. Gusarevich D. A. Dorofeev P. Ch. Zavadskiy A. B. Zakhidov O. G. Zvereva I. N. Isakov I. D. Kamenskikh U. R. Karimov I. V. Kondrakova A. V. Kuroyedov S. N. Lanin Dzh. N. Lovpache I. A. Loskutov E. V. Molchanova Z. M. Nagornova O. N. Onufriychuk S. Yu. Petrov Yu. I. Rozhko A. V. Seleznev A. S. Khokhlova I. V. Shaposhnikova A. P. Shakhalova R. V. Shevchuk |
| author_facet | R. V. Avdeev A. S. Alexandrov M. U. Arapiev N. A. Bakunina A. S. Basinskiy D. A. Belaya A. Y. Brezhnev N. V. Volkova L. M. Gabdrakhmanov I. R. Gazizova A. B. Galimova V. V. Garkavenko A. M. Getmanova V. V. Gorodnichiy A. A. Gusarevich D. A. Dorofeev P. Ch. Zavadskiy A. B. Zakhidov O. G. Zvereva I. N. Isakov I. D. Kamenskikh U. R. Karimov I. V. Kondrakova A. V. Kuroyedov S. N. Lanin Dzh. N. Lovpache I. A. Loskutov E. V. Molchanova Z. M. Nagornova O. N. Onufriychuk S. Yu. Petrov Yu. I. Rozhko A. V. Seleznev A. S. Khokhlova I. V. Shaposhnikova A. P. Shakhalova R. V. Shevchuk |
| author_sort | R. V. Avdeev |
| collection | DOAJ |
| description | Purpose: to set out morphofunctional differences in the ophthalmic status between suspected glaucoma (SG) and the initial stage of primary open angle glaucoma (POAG), determine the values of interocular asymmetry of the analyzed parameters of fellow eyes and create a model able to distinguish, with high accuracy, between healthy subjects, SG patients and POAG patients relying on a few independent parameters. Material and methods. A multicenter study performed between July and November, 2016, by 34 research and clinical facilities of four countries (Russia, Belarus, Uzbekistan, and Moldova) involved 501 patients (824 eyes), of which 362 (72 %) were female and 139 (28 %) male. The main analyzed group consisted of 128 eyes with SG, 228 eyes with early stage POAG and 145 eyes of healthy subjects (the control group with comparable sex and age distribution and no history of glaucoma). The fellow-eye symmetry analysis group involved 190 eyes with SG, 336 eyes with early stage POAG and 220 eyes of 110 subjects with no glaucoma. Results. Differences were found in the structural and functional ophthalmologic parameters in early-stage POAG, SG, and the absence of glaucoma. The precision of SG and early POAG may be increased by cumulative consideration of several clinical parameters. Conclusions. The sensitivity and specificity of the integral index of condition prognostication increases when several parameters are analyzed simultaneously, as compared to the separate analysis of constituents. For citations: Avdeev R.V., Alexandrov A.S., Arapiev M.U., et al. Suspected glaucoma and early stage glaucoma: differential diagnostic criteria. Russian ophthalmological journal. 2017; 10 (4): 5-15. doi: 10.21516/2072-0076-2017-10-4-5-15 (In Russian). |
| format | Article |
| id | doaj-art-bc2b71cc76e64195969165204ed4e627 |
| institution | DOAJ |
| issn | 2072-0076 2587-5760 |
| language | Russian |
| publishDate | 2018-10-01 |
| publisher | Real Time Ltd |
| record_format | Article |
| series | Российский офтальмологический журнал |
| spelling | doaj-art-bc2b71cc76e64195969165204ed4e6272025-08-20T02:54:10ZrusReal Time LtdРоссийский офтальмологический журнал2072-00762587-57602018-10-0110451510.21516/2072-0076-2017-10-4-5-15117Suspected glaucoma and early stage glaucoma: differential diagnostic criteriaR. V. Avdeev0A. S. Alexandrov1M. U. Arapiev2N. A. Bakunina3A. S. Basinskiy4D. A. Belaya5A. Y. Brezhnev6N. V. Volkova7L. M. Gabdrakhmanov8I. R. Gazizova9A. B. Galimova10V. V. Garkavenko11A. M. Getmanova12V. V. Gorodnichiy13A. A. Gusarevich14D. A. Dorofeev15P. Ch. Zavadskiy16A. B. Zakhidov17O. G. Zvereva18I. N. Isakov19I. D. Kamenskikh20U. R. Karimov21I. V. Kondrakova22A. V. Kuroyedov23S. N. Lanin24Dzh. N. Lovpache25I. A. Loskutov26E. V. Molchanova27Z. M. Nagornova28O. N. Onufriychuk29S. Yu. Petrov30Yu. I. Rozhko31A. V. Seleznev32A. S. Khokhlova33I. V. Shaposhnikova34A. P. Shakhalova35R. V. Shevchuk36Voronezh Burdenko State Medical Academy, Voronezh, RussiaMandryka Central Clinical Hospital, Ministry of Defense, Moscow, RussiaMoscow Helmholtz Research Institute of Eye Diseases, Moscow, RussiaPirogov City State Clinical Hospital No. 1, Moscow, RussiaProf. Basynsky Private Ophthalmology Center, Orel, RussiaP.A. Bayandin Regional Clinical Hospital, Murmansk, RussiaKursk State Medical University, Kursk, RussiaS. Fyodorov Eye Microsurgery Center, Irkutsk, RussiaEroshevsky Samara Regional Clinical Ophthalmologic Hospital, Samara, RussiaMechnikov North-West Federal Medical and Research University, St. Petersburg, RussiaAll-Russian Eye and Plastic Surgery Center, Ufa, RussiaVoyno-Yasenetsky State Medical University, Krasnoyarsk, RussiaRegional Eye Hospital N 1, Bryansk, RussiaMandryka Central Clinical Hospital, Ministry of Defense, Moscow, RussiaRegional Railway Clinical Hospital, Novosibirsk, RussiaRegional Ophthalmology Clinical Hospital N 3, Chelyabinsk, RussiaMedical Center “New Vision”, Minsk, BelarusOphthalmosurgery Medical Center “SAIF-OPTIMA”, Tashkent, UzbekistanState Tatarstan Republican Hospital, Kazan, RussiaKryukov Medical and Diagnostic Center, Novokuznetsk, RussiaSaratov Razumovsky State Medical University, Saratov, RussiaGulistan Kuz, Ophthalmology Hospital, Gulistan, UzbekistanMandryka Central Clinical Hospital, Ministry of Defense, Moscow, RussiaMandryka Central Clinical Hospital, Ministry of Defense, Moscow, RussiaMakarov State Ophthalmology Clinical Hospital, Krasnoyarsk, RussiaMoscow Helmholtz Research Institute of Eye Diseases, Moscow, RussiaRussian Railway Clinical and Research Medical Center, Moscow, RussiaOmsk State Medical Academy, Omsk, RussiaIvanovo State Medical Academy, Ivanovo, RussiaOphthalmic Diagnostic City Center N 7, St. Petersburg, RussiaScientific and Research State Ophthalmology Institute, Moscow, RussiaState Republican Scientific Research Center for Radiation Medicine and Human Ecology, Gomel, BelarusIvanovo State Medical Academy, Ivanovo, RussiaPacific State Medical University, Vladivostok, RussiaMedical Clinical Center “Good Vision”, Kemerovo, RussiaMedical Clinical Center “Tonus Amaris”, Nizhny Novgorod, RussiaState Health Institution “Institute of Emergency Care”, Chisinau, MoldovaPurpose: to set out morphofunctional differences in the ophthalmic status between suspected glaucoma (SG) and the initial stage of primary open angle glaucoma (POAG), determine the values of interocular asymmetry of the analyzed parameters of fellow eyes and create a model able to distinguish, with high accuracy, between healthy subjects, SG patients and POAG patients relying on a few independent parameters. Material and methods. A multicenter study performed between July and November, 2016, by 34 research and clinical facilities of four countries (Russia, Belarus, Uzbekistan, and Moldova) involved 501 patients (824 eyes), of which 362 (72 %) were female and 139 (28 %) male. The main analyzed group consisted of 128 eyes with SG, 228 eyes with early stage POAG and 145 eyes of healthy subjects (the control group with comparable sex and age distribution and no history of glaucoma). The fellow-eye symmetry analysis group involved 190 eyes with SG, 336 eyes with early stage POAG and 220 eyes of 110 subjects with no glaucoma. Results. Differences were found in the structural and functional ophthalmologic parameters in early-stage POAG, SG, and the absence of glaucoma. The precision of SG and early POAG may be increased by cumulative consideration of several clinical parameters. Conclusions. The sensitivity and specificity of the integral index of condition prognostication increases when several parameters are analyzed simultaneously, as compared to the separate analysis of constituents. For citations: Avdeev R.V., Alexandrov A.S., Arapiev M.U., et al. Suspected glaucoma and early stage glaucoma: differential diagnostic criteria. Russian ophthalmological journal. 2017; 10 (4): 5-15. doi: 10.21516/2072-0076-2017-10-4-5-15 (In Russian).https://roj.igb.ru/jour/article/view/117глаукомаподозрение на глаукомуначальная глаукомадиагностикалечениепрогнозированиевероятностьroc-криваяglaucomasuspected glaucomaearly glaucomadiagnosistreatmentpredictionprobabilityroc curve |
| spellingShingle | R. V. Avdeev A. S. Alexandrov M. U. Arapiev N. A. Bakunina A. S. Basinskiy D. A. Belaya A. Y. Brezhnev N. V. Volkova L. M. Gabdrakhmanov I. R. Gazizova A. B. Galimova V. V. Garkavenko A. M. Getmanova V. V. Gorodnichiy A. A. Gusarevich D. A. Dorofeev P. Ch. Zavadskiy A. B. Zakhidov O. G. Zvereva I. N. Isakov I. D. Kamenskikh U. R. Karimov I. V. Kondrakova A. V. Kuroyedov S. N. Lanin Dzh. N. Lovpache I. A. Loskutov E. V. Molchanova Z. M. Nagornova O. N. Onufriychuk S. Yu. Petrov Yu. I. Rozhko A. V. Seleznev A. S. Khokhlova I. V. Shaposhnikova A. P. Shakhalova R. V. Shevchuk Suspected glaucoma and early stage glaucoma: differential diagnostic criteria Российский офтальмологический журнал глаукома подозрение на глаукому начальная глаукома диагностика лечение прогнозирование вероятность roc-кривая glaucoma suspected glaucoma early glaucoma diagnosis treatment prediction probability roc curve |
| title | Suspected glaucoma and early stage glaucoma: differential diagnostic criteria |
| title_full | Suspected glaucoma and early stage glaucoma: differential diagnostic criteria |
| title_fullStr | Suspected glaucoma and early stage glaucoma: differential diagnostic criteria |
| title_full_unstemmed | Suspected glaucoma and early stage glaucoma: differential diagnostic criteria |
| title_short | Suspected glaucoma and early stage glaucoma: differential diagnostic criteria |
| title_sort | suspected glaucoma and early stage glaucoma differential diagnostic criteria |
| topic | глаукома подозрение на глаукому начальная глаукома диагностика лечение прогнозирование вероятность roc-кривая glaucoma suspected glaucoma early glaucoma diagnosis treatment prediction probability roc curve |
| url | https://roj.igb.ru/jour/article/view/117 |
| work_keys_str_mv | AT rvavdeev suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT asalexandrov suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT muarapiev suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT nabakunina suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT asbasinskiy suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT dabelaya suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT aybrezhnev suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT nvvolkova suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT lmgabdrakhmanov suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT irgazizova suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT abgalimova suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT vvgarkavenko suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT amgetmanova suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT vvgorodnichiy suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT aagusarevich suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT dadorofeev suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT pchzavadskiy suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT abzakhidov suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT ogzvereva suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT inisakov suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT idkamenskikh suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT urkarimov suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT ivkondrakova suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT avkuroyedov suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT snlanin suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT dzhnlovpache suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT ialoskutov suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT evmolchanova suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT zmnagornova suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT ononufriychuk suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT syupetrov suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT yuirozhko suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT avseleznev suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT askhokhlova suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT ivshaposhnikova suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT apshakhalova suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria AT rvshevchuk suspectedglaucomaandearlystageglaucomadifferentialdiagnosticcriteria |