Fast and accurate short-read alignment with hybrid hash-tree data structure

Abstract Rapidly increasing the amount of short-read data generated by NGSs (new-generation sequencers) calls for the development of fast and accurate read alignment programs. The programs based on the hash table (BLAST) and Burrows-Wheeler transform (bwa-mem) are used, and the latter is known to gi...

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Bibliographic Details
Main Authors: Junichiro Makino, Toshikazu Ebisuzaki, Ryutaro Himeno, Yoshihide Hayashizaki
Format: Article
Language:English
Published: BioMed Central 2024-10-01
Series:Genomics & Informatics
Subjects:
Online Access:https://doi.org/10.1186/s44342-024-00012-5
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