Surface Enhanced Raman Scattering (SERS) for the Detection of Oxidative Stress Markers Using Si Nanowires (SiNWs)/Ag Nanostructures Fabricated by Metal Assisted Chemical Etching (MACE)

In this work, silicon nanowires were constructed by metal-assisted chemical etching and decorated with silver nanoparticles and used as substrates for the SERS determination of oxidative stress markers, namely glutathione, malondialdehyde and catalase. The assays were sensitive, with detection limit...

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Main Authors: Ioannis Kochylas, Anastasia Kanioura, Georgia Geka, Vlassios Likodimos, Spiros Gardelis, Anastasios Dimitriou, Nikolaos Papanikolaou, Sotirios Kakabakos, Panagiota Petrou
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Proceedings
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Online Access:https://www.mdpi.com/2504-3900/97/1/170
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author Ioannis Kochylas
Anastasia Kanioura
Georgia Geka
Vlassios Likodimos
Spiros Gardelis
Anastasios Dimitriou
Nikolaos Papanikolaou
Sotirios Kakabakos
Panagiota Petrou
author_facet Ioannis Kochylas
Anastasia Kanioura
Georgia Geka
Vlassios Likodimos
Spiros Gardelis
Anastasios Dimitriou
Nikolaos Papanikolaou
Sotirios Kakabakos
Panagiota Petrou
author_sort Ioannis Kochylas
collection DOAJ
description In this work, silicon nanowires were constructed by metal-assisted chemical etching and decorated with silver nanoparticles and used as substrates for the SERS determination of oxidative stress markers, namely glutathione, malondialdehyde and catalase. The assays were sensitive, with detection limits of 50 and 3.2 nM for glutathione and malondialdehyde, respectively, and 0.5 μg/mL for catalase, indicating the capability of the proposed substrates to be implemented for the determination of various oxidative stress markers.
format Article
id doaj-art-bc29bb4e85a14b259a43030dfadf5e75
institution DOAJ
issn 2504-3900
language English
publishDate 2024-04-01
publisher MDPI AG
record_format Article
series Proceedings
spelling doaj-art-bc29bb4e85a14b259a43030dfadf5e752025-08-20T02:51:07ZengMDPI AGProceedings2504-39002024-04-0197117010.3390/proceedings2024097170Surface Enhanced Raman Scattering (SERS) for the Detection of Oxidative Stress Markers Using Si Nanowires (SiNWs)/Ag Nanostructures Fabricated by Metal Assisted Chemical Etching (MACE)Ioannis Kochylas0Anastasia Kanioura1Georgia Geka2Vlassios Likodimos3Spiros Gardelis4Anastasios Dimitriou5Nikolaos Papanikolaou6Sotirios Kakabakos7Panagiota Petrou8Section of Condensed Matter Physics, Department of Physics, National and Kapodistrian University of Athens, University Campus, 15784 Athens, GreeceImmunoassays/Immunosensors Laboratory, Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, NCSR “Demokritos”, 15341 Athens, GreeceImmunoassays/Immunosensors Laboratory, Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, NCSR “Demokritos”, 15341 Athens, GreeceSection of Condensed Matter Physics, Department of Physics, National and Kapodistrian University of Athens, University Campus, 15784 Athens, GreeceSection of Condensed Matter Physics, Department of Physics, National and Kapodistrian University of Athens, University Campus, 15784 Athens, GreeceInstitute of Nanoscience & Nanotechnology, NCSR “Demokritos”, 15341 Athens, GreeceInstitute of Nanoscience & Nanotechnology, NCSR “Demokritos”, 15341 Athens, GreeceImmunoassays/Immunosensors Laboratory, Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, NCSR “Demokritos”, 15341 Athens, GreeceImmunoassays/Immunosensors Laboratory, Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, NCSR “Demokritos”, 15341 Athens, GreeceIn this work, silicon nanowires were constructed by metal-assisted chemical etching and decorated with silver nanoparticles and used as substrates for the SERS determination of oxidative stress markers, namely glutathione, malondialdehyde and catalase. The assays were sensitive, with detection limits of 50 and 3.2 nM for glutathione and malondialdehyde, respectively, and 0.5 μg/mL for catalase, indicating the capability of the proposed substrates to be implemented for the determination of various oxidative stress markers.https://www.mdpi.com/2504-3900/97/1/170SERSMACEoxidative stressglutathionemalondialdehydecatalase
spellingShingle Ioannis Kochylas
Anastasia Kanioura
Georgia Geka
Vlassios Likodimos
Spiros Gardelis
Anastasios Dimitriou
Nikolaos Papanikolaou
Sotirios Kakabakos
Panagiota Petrou
Surface Enhanced Raman Scattering (SERS) for the Detection of Oxidative Stress Markers Using Si Nanowires (SiNWs)/Ag Nanostructures Fabricated by Metal Assisted Chemical Etching (MACE)
Proceedings
SERS
MACE
oxidative stress
glutathione
malondialdehyde
catalase
title Surface Enhanced Raman Scattering (SERS) for the Detection of Oxidative Stress Markers Using Si Nanowires (SiNWs)/Ag Nanostructures Fabricated by Metal Assisted Chemical Etching (MACE)
title_full Surface Enhanced Raman Scattering (SERS) for the Detection of Oxidative Stress Markers Using Si Nanowires (SiNWs)/Ag Nanostructures Fabricated by Metal Assisted Chemical Etching (MACE)
title_fullStr Surface Enhanced Raman Scattering (SERS) for the Detection of Oxidative Stress Markers Using Si Nanowires (SiNWs)/Ag Nanostructures Fabricated by Metal Assisted Chemical Etching (MACE)
title_full_unstemmed Surface Enhanced Raman Scattering (SERS) for the Detection of Oxidative Stress Markers Using Si Nanowires (SiNWs)/Ag Nanostructures Fabricated by Metal Assisted Chemical Etching (MACE)
title_short Surface Enhanced Raman Scattering (SERS) for the Detection of Oxidative Stress Markers Using Si Nanowires (SiNWs)/Ag Nanostructures Fabricated by Metal Assisted Chemical Etching (MACE)
title_sort surface enhanced raman scattering sers for the detection of oxidative stress markers using si nanowires sinws ag nanostructures fabricated by metal assisted chemical etching mace
topic SERS
MACE
oxidative stress
glutathione
malondialdehyde
catalase
url https://www.mdpi.com/2504-3900/97/1/170
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