Association of 5α-reductase inhibitor prescription with immunotherapy efficacy in metastatic renal cell carcinoma: a multicenter retrospective analysis

Background Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of metastatic renal cell carcinoma (mRCC), but response rates remain heterogeneous, and reliable predictive biomarkers are lacking. Recent studies suggest that androgen receptor (AR) signaling plays a role in regulating...

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Main Authors: Lin Yang, Hai Huang, Qiong Wang, Peng Wu, Ke Chen, Weijia Li, Bisheng Cheng, Jilin Wu, Jianghua Yang, WenTai Shangguan, Wenxue Huang, Cunzhen Ma, Zhuohang Li, Boyuan Sun
Format: Article
Language:English
Published: BMJ Publishing Group 2025-02-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/2/e011154.full
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