Achieving the fast track 90-90-90 and 95-95-95 targets in sub-Saharan Africa: A rapid review

Background: The Joint United Nations Programme on HIV/AIDS (UNAIDS) set targets for 95% of people living with human immunodeficiency virus (HIV) infection to know their status, 95% to receive antiretroviral therapy (ART) and 95% to achieve viral suppression. These targets mirror the 90-90-90 targets...

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Main Authors: Celenkosini T. Nxumalo, Usangiphile Buthelezi, Hlolisile Chiya, Mokgadi U. Makgobole, Nomakhosi Mpofana, Themba Mgwaba, Zamasomi Luvuno
Format: Article
Language:English
Published: AOSIS 2025-04-01
Series:Journal of Public Health in Africa
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Online Access:https://publichealthinafrica.org/index.php/jphia/article/view/691
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author Celenkosini T. Nxumalo
Usangiphile Buthelezi
Hlolisile Chiya
Mokgadi U. Makgobole
Nomakhosi Mpofana
Themba Mgwaba
Zamasomi Luvuno
author_facet Celenkosini T. Nxumalo
Usangiphile Buthelezi
Hlolisile Chiya
Mokgadi U. Makgobole
Nomakhosi Mpofana
Themba Mgwaba
Zamasomi Luvuno
author_sort Celenkosini T. Nxumalo
collection DOAJ
description Background: The Joint United Nations Programme on HIV/AIDS (UNAIDS) set targets for 95% of people living with human immunodeficiency virus (HIV) infection to know their status, 95% to receive antiretroviral therapy (ART) and 95% to achieve viral suppression. These targets mirror the 90-90-90 targets that were aimed to be met by 2020 to end AIDS as a public health threat by 2030. Aim: The study aims to synthesise evidence on recommendations, best practices and challenges in achieving 90-90-90 escalated to 95-95-95 fast-track targets in sub-Saharan Africa. Setting: The review included empirical evidence from sub-Saharan Africa. Method: We followed Arksey and O’Malley’s methodological framework for this scoping review. A systematic search of relevant articles was conducted using electronic databases such as Scopus, EBSCOHost, PubMed, Science Direct and Sabinet. The results were reported using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flow diagram. Results: There were 6943 relevant study titles that were identified from the five databases. Following duplicates removal, title and abstract screening, 31 articles were included for full-text review. A combination of qualitative, quantitative and mixed methods studies were included. Conclusion: The 90-90-90 targets have been achieved in part, but challenges remain, particularly for key and vulnerable populations. Even as successes and challenges towards ‘90-90-90 by 2020’ are outlined, new fast-track ‘95-95-95 by 2030’ targets have been established because of concerns that the original targets may not have achieved epidemic control. Contribution: The findings of this review have implications for policy and practice related to interventions to facilitate the realisation of HIV epidemic control as outlined by the UNAIDS 95-95-95 treatment cascade.
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institution Kabale University
issn 2038-9922
2038-9930
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publishDate 2025-04-01
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series Journal of Public Health in Africa
spelling doaj-art-bc1954c781ef40bebddaf0d47a1b15f52025-08-20T03:29:27ZengAOSISJournal of Public Health in Africa2038-99222038-99302025-04-01161e1e810.4102/jphia.v16i1.691851Achieving the fast track 90-90-90 and 95-95-95 targets in sub-Saharan Africa: A rapid reviewCelenkosini T. Nxumalo0Usangiphile Buthelezi1Hlolisile Chiya2Mokgadi U. Makgobole3Nomakhosi Mpofana4Themba Mgwaba5Zamasomi Luvuno6Department of Research Development and Postgraduate Support, Office of the DVC Research and Innovation, University of the Western Cape, Cape TownCentre for Rural Health, School of Nursing and Public Health, University of KwaZulu-Natal, DurbanDiscipline of Nursing, School of Nursing and Public Health, University of KwaZulu-Natal, DurbanDepartment of Somatology, Faculty of Health Sciences, Durban University of Technology, DurbanDepartment of Somatology, Faculty of Health Sciences, Durban University of Technology, DurbanSchool of Built Environment, College of Humanities, University of KwaZulu-Natal, DurbanDiscipline of Nursing, School of Nursing and Public Health, University of KwaZulu-Natal, DurbanBackground: The Joint United Nations Programme on HIV/AIDS (UNAIDS) set targets for 95% of people living with human immunodeficiency virus (HIV) infection to know their status, 95% to receive antiretroviral therapy (ART) and 95% to achieve viral suppression. These targets mirror the 90-90-90 targets that were aimed to be met by 2020 to end AIDS as a public health threat by 2030. Aim: The study aims to synthesise evidence on recommendations, best practices and challenges in achieving 90-90-90 escalated to 95-95-95 fast-track targets in sub-Saharan Africa. Setting: The review included empirical evidence from sub-Saharan Africa. Method: We followed Arksey and O’Malley’s methodological framework for this scoping review. A systematic search of relevant articles was conducted using electronic databases such as Scopus, EBSCOHost, PubMed, Science Direct and Sabinet. The results were reported using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flow diagram. Results: There were 6943 relevant study titles that were identified from the five databases. Following duplicates removal, title and abstract screening, 31 articles were included for full-text review. A combination of qualitative, quantitative and mixed methods studies were included. Conclusion: The 90-90-90 targets have been achieved in part, but challenges remain, particularly for key and vulnerable populations. Even as successes and challenges towards ‘90-90-90 by 2020’ are outlined, new fast-track ‘95-95-95 by 2030’ targets have been established because of concerns that the original targets may not have achieved epidemic control. Contribution: The findings of this review have implications for policy and practice related to interventions to facilitate the realisation of HIV epidemic control as outlined by the UNAIDS 95-95-95 treatment cascade.https://publichealthinafrica.org/index.php/jphia/article/view/691hiv90-90-90hiv treatment cascade95-95-95unaids fast-track targetsbest practicesrecommendationssuccesseschallenges
spellingShingle Celenkosini T. Nxumalo
Usangiphile Buthelezi
Hlolisile Chiya
Mokgadi U. Makgobole
Nomakhosi Mpofana
Themba Mgwaba
Zamasomi Luvuno
Achieving the fast track 90-90-90 and 95-95-95 targets in sub-Saharan Africa: A rapid review
Journal of Public Health in Africa
hiv
90-90-90
hiv treatment cascade
95-95-95
unaids fast-track targets
best practices
recommendations
successes
challenges
title Achieving the fast track 90-90-90 and 95-95-95 targets in sub-Saharan Africa: A rapid review
title_full Achieving the fast track 90-90-90 and 95-95-95 targets in sub-Saharan Africa: A rapid review
title_fullStr Achieving the fast track 90-90-90 and 95-95-95 targets in sub-Saharan Africa: A rapid review
title_full_unstemmed Achieving the fast track 90-90-90 and 95-95-95 targets in sub-Saharan Africa: A rapid review
title_short Achieving the fast track 90-90-90 and 95-95-95 targets in sub-Saharan Africa: A rapid review
title_sort achieving the fast track 90 90 90 and 95 95 95 targets in sub saharan africa a rapid review
topic hiv
90-90-90
hiv treatment cascade
95-95-95
unaids fast-track targets
best practices
recommendations
successes
challenges
url https://publichealthinafrica.org/index.php/jphia/article/view/691
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