A single-dose mRNA vaccine encoding the classical swine fever virus E2-ECD induces durable protective immunity in rabbits

A single-dose mRNA vaccine encoding the classical swine fever virus E2-ECD induces durable protective immunity in rabbits

Abstract Classical swine fever virus (CSFV) spreads in domestic and wild pig populations, causing significant economic losses in the swine industry. Despite the global implementation of live attenuated vaccines, CSFV remains a persistent threat, with sporadic outbreaks reported annually. A major lim...

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Bibliographic Details
Main Authors: Li-Jun Bian, Yu Tang, Fan Yang, Hong Tian, Qin Peng, Ming-Liang Tang, Yi-Zhen Chen, Tian Xia, Shu Li, Hai-Xue Zheng, Hong-Bing Shu, Mi Li
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Veterinary Research
Subjects:
Classical swine fever virus (CSFV)
mRNA vaccine
E2 protein
protective immunity
Online Access:https://doi.org/10.1186/s13567-025-01581-1
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https://doi.org/10.1186/s13567-025-01581-1

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