Effects of Tai Chi and Qigong intervention on anxiety and stress in diabetic and hypertensive Brazilian patients: a randomized controlled trial

ABSTRACT Objective: This study investigated the effects of Tai Chi/Qigong practice over 13 weeks on anxiety and perceived stress levels in middle-aged or older Brazilian hypertensive and diabetic individuals assisted in a primary healthcare setting. Methods: Ninety-one patients with diabetes melli...

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Main Authors: Laís Renata Almeida Cezário Santos, Anderson Taíra, Rosana de Fátima Possobon, Marcelo de Castro Meneghim, Chien-Lin Su, Paola Lavin, Soham Rej, Gláucia Maria Bovi Ambrosano, Karine Laura Cortellazzi
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Language:English
Published: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2025-03-01
Series:Einstein (São Paulo)
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082025000100212&tlng=en
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author Laís Renata Almeida Cezário Santos
Anderson Taíra
Rosana de Fátima Possobon
Marcelo de Castro Meneghim
Chien-Lin Su
Paola Lavin
Soham Rej
Gláucia Maria Bovi Ambrosano
Karine Laura Cortellazzi
author_facet Laís Renata Almeida Cezário Santos
Anderson Taíra
Rosana de Fátima Possobon
Marcelo de Castro Meneghim
Chien-Lin Su
Paola Lavin
Soham Rej
Gláucia Maria Bovi Ambrosano
Karine Laura Cortellazzi
author_sort Laís Renata Almeida Cezário Santos
collection DOAJ
description ABSTRACT Objective: This study investigated the effects of Tai Chi/Qigong practice over 13 weeks on anxiety and perceived stress levels in middle-aged or older Brazilian hypertensive and diabetic individuals assisted in a primary healthcare setting. Methods: Ninety-one patients with diabetes mellitus and/or hypertension diagnosed and followed up at a primary care center were randomized to the Tai Chi/Qigong intervention (n = 45) or waitlist (n = 46) group for 13 weeks. Outcome measures were collected at baseline and at 6 and 13 weeks for anxiety (State-Trait Anxiety Inventory [STAI]) and stress (Perceived Stress Scale - PSS14). The primary endpoint of the study was 13 weeks. We used a linear mixed-effects model to analyze the primary and secondary outcomes, considering the treatment group and time as covariates and treating the subject as a random effect. Results: Of the included 91 participants, 53 completed the 6-week assessment, and 42 completed the 13-week assessment. After 13 weeks, the Tai Chi/Qigong Group had lower scores for anxiety (STAI Estimate = -6.421; SD = 2.679; 95% confidence interval (95%CI) = [-11.615,-1.224]; p = 0.018) and stress (PSS14 Estimate = -9.290; SD= 2.262; 95%CI= [-13.678,-4.906]; p<0.001). Conclusion: A 13-week Tai Chi/Qigong intervention was efficacious in lowering anxiety and perceived stress scores in middle-aged and older patients with diabetes mellitus and hypertension and can potentially be used in primary care centers as an adjunct therapy. Trial registration: Brazilian Registry of Clinical Trials (ReBEC), Identifier: U1111-1276-1787.
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spelling doaj-art-bc09d6561d3a4eaf92bf3c0ff96c8c6a2025-08-20T03:06:48ZengInstituto Israelita de Ensino e Pesquisa Albert EinsteinEinstein (São Paulo)2317-63852025-03-012310.31744/einstein_journal/2025ao1076Effects of Tai Chi and Qigong intervention on anxiety and stress in diabetic and hypertensive Brazilian patients: a randomized controlled trialLaís Renata Almeida Cezário Santoshttps://orcid.org/0000-0002-0737-2857Anderson Taírahttps://orcid.org/0000-0001-8805-5847Rosana de Fátima Possobonhttps://orcid.org/0000-0001-6179-3030Marcelo de Castro Meneghimhttps://orcid.org/0000-0003-2673-3627Chien-Lin Suhttps://orcid.org/0000-0002-0664-8583Paola Lavinhttps://orcid.org/0000-0003-0733-9261Soham Rejhttps://orcid.org/0000-0002-3908-9124Gláucia Maria Bovi Ambrosanohttps://orcid.org/0000-0001-5950-6370Karine Laura Cortellazzihttps://orcid.org/0000-0001-9584-9477ABSTRACT Objective: This study investigated the effects of Tai Chi/Qigong practice over 13 weeks on anxiety and perceived stress levels in middle-aged or older Brazilian hypertensive and diabetic individuals assisted in a primary healthcare setting. Methods: Ninety-one patients with diabetes mellitus and/or hypertension diagnosed and followed up at a primary care center were randomized to the Tai Chi/Qigong intervention (n = 45) or waitlist (n = 46) group for 13 weeks. Outcome measures were collected at baseline and at 6 and 13 weeks for anxiety (State-Trait Anxiety Inventory [STAI]) and stress (Perceived Stress Scale - PSS14). The primary endpoint of the study was 13 weeks. We used a linear mixed-effects model to analyze the primary and secondary outcomes, considering the treatment group and time as covariates and treating the subject as a random effect. Results: Of the included 91 participants, 53 completed the 6-week assessment, and 42 completed the 13-week assessment. After 13 weeks, the Tai Chi/Qigong Group had lower scores for anxiety (STAI Estimate = -6.421; SD = 2.679; 95% confidence interval (95%CI) = [-11.615,-1.224]; p = 0.018) and stress (PSS14 Estimate = -9.290; SD= 2.262; 95%CI= [-13.678,-4.906]; p<0.001). Conclusion: A 13-week Tai Chi/Qigong intervention was efficacious in lowering anxiety and perceived stress scores in middle-aged and older patients with diabetes mellitus and hypertension and can potentially be used in primary care centers as an adjunct therapy. Trial registration: Brazilian Registry of Clinical Trials (ReBEC), Identifier: U1111-1276-1787.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082025000100212&tlng=enTai jiQigongPerceived stress scaleAnxietyHypertensionDiabetes mellitusPrimary health careOutcome assessment, health careStress, psychologicalMiddle-agedAgedComplementary therapeutic methods
spellingShingle Laís Renata Almeida Cezário Santos
Anderson Taíra
Rosana de Fátima Possobon
Marcelo de Castro Meneghim
Chien-Lin Su
Paola Lavin
Soham Rej
Gláucia Maria Bovi Ambrosano
Karine Laura Cortellazzi
Effects of Tai Chi and Qigong intervention on anxiety and stress in diabetic and hypertensive Brazilian patients: a randomized controlled trial
Einstein (São Paulo)
Tai ji
Qigong
Perceived stress scale
Anxiety
Hypertension
Diabetes mellitus
Primary health care
Outcome assessment, health care
Stress, psychological
Middle-aged
Aged
Complementary therapeutic methods
title Effects of Tai Chi and Qigong intervention on anxiety and stress in diabetic and hypertensive Brazilian patients: a randomized controlled trial
title_full Effects of Tai Chi and Qigong intervention on anxiety and stress in diabetic and hypertensive Brazilian patients: a randomized controlled trial
title_fullStr Effects of Tai Chi and Qigong intervention on anxiety and stress in diabetic and hypertensive Brazilian patients: a randomized controlled trial
title_full_unstemmed Effects of Tai Chi and Qigong intervention on anxiety and stress in diabetic and hypertensive Brazilian patients: a randomized controlled trial
title_short Effects of Tai Chi and Qigong intervention on anxiety and stress in diabetic and hypertensive Brazilian patients: a randomized controlled trial
title_sort effects of tai chi and qigong intervention on anxiety and stress in diabetic and hypertensive brazilian patients a randomized controlled trial
topic Tai ji
Qigong
Perceived stress scale
Anxiety
Hypertension
Diabetes mellitus
Primary health care
Outcome assessment, health care
Stress, psychological
Middle-aged
Aged
Complementary therapeutic methods
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082025000100212&tlng=en
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