Traditional Chinese medicine for adhesive intestinal obstruction: theory, methods and mechanisms of action
Adhesive intestinal obstruction (AIO) represents a common postoperative complication, particularly following abdominal surgery, with reported incidence rates varying between 50 and 80%. Traditional Chinese Medicine (TCM) has proven clinically effective in managing AIO, offering diverse therapeutic a...
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Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1573655/full |
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| author | Pengfei Zhou Huiju Yang Jiawen Wang Mingming Sun Shuai Yan |
| author_facet | Pengfei Zhou Huiju Yang Jiawen Wang Mingming Sun Shuai Yan |
| author_sort | Pengfei Zhou |
| collection | DOAJ |
| description | Adhesive intestinal obstruction (AIO) represents a common postoperative complication, particularly following abdominal surgery, with reported incidence rates varying between 50 and 80%. Traditional Chinese Medicine (TCM) has proven clinically effective in managing AIO, offering diverse therapeutic approaches that facilitate multi-pathway and multi-target treatment. Clinical evidence consistently supports the favorable safety profile of Traditional Chinese Medicine (TCM). Nevertheless, several critical challenges remain to be addressed, including its complex multi-component nature, insufficiently elucidated mechanisms of action, lack of precise dosage standards, inconsistencies in decoction preparation methods, inconvenient administration procedures, and a paucity of large-scale, multicenter clinical trials with robust evidence. These barriers hinder the widespread adoption and clinical integration of TCM. Moving forward, large-scale, multicenter studies are essential to further investigate the safety and efficacy of TCM. Moreover, reforms in its administration methods and deeper exploration of its mechanisms in AIO treatment are crucial. |
| format | Article |
| id | doaj-art-bbff7cd89fdf4cb9863f7416c357e942 |
| institution | DOAJ |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-bbff7cd89fdf4cb9863f7416c357e9422025-08-20T02:55:16ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-05-011210.3389/fmed.2025.15736551573655Traditional Chinese medicine for adhesive intestinal obstruction: theory, methods and mechanisms of actionPengfei Zhou0Huiju Yang1Jiawen Wang2Mingming Sun3Shuai Yan4Department of Anorectal Surgery, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaDepartment of Aolorectal Surgery, The Third Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, ChinaDepartment of Anorectal Surgery, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaDepartment of Anorectal Surgery, Suzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Suzhou, ChinaDepartment of Anorectal Surgery, Suzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Suzhou, ChinaAdhesive intestinal obstruction (AIO) represents a common postoperative complication, particularly following abdominal surgery, with reported incidence rates varying between 50 and 80%. Traditional Chinese Medicine (TCM) has proven clinically effective in managing AIO, offering diverse therapeutic approaches that facilitate multi-pathway and multi-target treatment. Clinical evidence consistently supports the favorable safety profile of Traditional Chinese Medicine (TCM). Nevertheless, several critical challenges remain to be addressed, including its complex multi-component nature, insufficiently elucidated mechanisms of action, lack of precise dosage standards, inconsistencies in decoction preparation methods, inconvenient administration procedures, and a paucity of large-scale, multicenter clinical trials with robust evidence. These barriers hinder the widespread adoption and clinical integration of TCM. Moving forward, large-scale, multicenter studies are essential to further investigate the safety and efficacy of TCM. Moreover, reforms in its administration methods and deeper exploration of its mechanisms in AIO treatment are crucial.https://www.frontiersin.org/articles/10.3389/fmed.2025.1573655/fulladhesive intestinal obstructiontraditional Chinese medicineChinese materia medicaacupuncturemechanism |
| spellingShingle | Pengfei Zhou Huiju Yang Jiawen Wang Mingming Sun Shuai Yan Traditional Chinese medicine for adhesive intestinal obstruction: theory, methods and mechanisms of action Frontiers in Medicine adhesive intestinal obstruction traditional Chinese medicine Chinese materia medica acupuncture mechanism |
| title | Traditional Chinese medicine for adhesive intestinal obstruction: theory, methods and mechanisms of action |
| title_full | Traditional Chinese medicine for adhesive intestinal obstruction: theory, methods and mechanisms of action |
| title_fullStr | Traditional Chinese medicine for adhesive intestinal obstruction: theory, methods and mechanisms of action |
| title_full_unstemmed | Traditional Chinese medicine for adhesive intestinal obstruction: theory, methods and mechanisms of action |
| title_short | Traditional Chinese medicine for adhesive intestinal obstruction: theory, methods and mechanisms of action |
| title_sort | traditional chinese medicine for adhesive intestinal obstruction theory methods and mechanisms of action |
| topic | adhesive intestinal obstruction traditional Chinese medicine Chinese materia medica acupuncture mechanism |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2025.1573655/full |
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