Advances in collagen fibrosis glomerulopathy
Collagenofibrotic glomerulopathy （CG）， also called Collagen Type Ⅲ glomerulopathy， which is a rare non-immune-mediated primary glomerular disease， characterized by abnormal accumulation of type Ⅲ collagen fibrils within the mesangial matrix and subendothelial space in the glomeruli. The major clinic...
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| Format: | Article |
| Language: | zho |
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Editorial Department of Journal of Clinical Nephrology
2025-02-01
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| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/article/doi/10.3969/j.issn.1671-2390.2025.02.011 |
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| Summary: | Collagenofibrotic glomerulopathy （CG）， also called Collagen Type Ⅲ glomerulopathy， which is a rare non-immune-mediated primary glomerular disease， characterized by abnormal accumulation of type Ⅲ collagen fibrils within the mesangial matrix and subendothelial space in the glomeruli. The major clinical manifestations are proteinuria， peripheral edema， hypertension and occasional progression to end-stage renal disease. The diagnosis is mainly based on electron microscopy. There is no effective treatment， and the overall prognosis is poor. For patients with end-stage renal disease， kidney transplantation may have a better prognosis. |
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| ISSN: | 1671-2390 |