The Contribution of α-Synuclein Spreading to Parkinson’s Disease Synaptopathy
Synaptopathies are diseases with synapse defects as shared pathogenic features, encompassing neurodegenerative disorders such as Parkinson’s disease (PD). In sporadic PD, the most common age-related neurodegenerative movement disorder, nigrostriatal dopaminergic deficits are responsible for the onse...
Saved in:
Main Authors: | Francesca Longhena, Gaia Faustini, Cristina Missale, Marina Pizzi, PierFranco Spano, Arianna Bellucci |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2017-01-01
|
Series: | Neural Plasticity |
Online Access: | http://dx.doi.org/10.1155/2017/5012129 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Mitochondrial Dysfunction and α-Synuclein Synaptic Pathology in Parkinson’s Disease: Who’s on First?
by: Michela Zaltieri, et al.
Published: (2015-01-01) -
Emerging targets of α-synuclein spreading in α-synucleinopathies: a review of mechanistic pathways and interventions
by: Grace Kuo, et al.
Published: (2025-01-01) -
Postmortem Interval Influences α-Synuclein Expression in Parkinson Disease Brain
by: Alexandra Dumitriu, et al.
Published: (2012-01-01) -
Dementia in Parkinson's Disease Correlates with α-Synuclein Pathology but Not with Cortical Astrogliosis
by: Simone A. van den Berge, et al.
Published: (2012-01-01) -
αSynuclein and Mitochondrial Dysfunction: A Pathogenic Partnership in Parkinson’s Disease?
by: David Protter, et al.
Published: (2012-01-01)