Phase-Dependent Modulation of Muscle Activity and Intermuscular Coupling During Walking in Patients After Stroke
Many patients experience motor and sensory impairments after stroke, leading to gait disturbances. Analysis of muscle modulation mode during walking can provide evidence for neurological changes after stroke, while how stroke affects individual muscle activity and muscular coordination in certain ga...
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IEEE
2023-01-01
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| Series: | IEEE Transactions on Neural Systems and Rehabilitation Engineering |
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| Online Access: | https://ieeexplore.ieee.org/document/10024397/ |
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| author | Yifan Li Yueling Lyu Rong Song |
| author_facet | Yifan Li Yueling Lyu Rong Song |
| author_sort | Yifan Li |
| collection | DOAJ |
| description | Many patients experience motor and sensory impairments after stroke, leading to gait disturbances. Analysis of muscle modulation mode during walking can provide evidence for neurological changes after stroke, while how stroke affects individual muscle activity and muscular coordination in certain gait sub-phases remains unclear. The purpose of the present study is to comprehensively investigate phase-dependent ankle muscle activity and intermuscular coupling patterns in post-stroke patients. In this experiment, 10 post-stroke patients, 10 young healthy subjects and 10 elderly healthy subjects were recruited. All subjects were asked to walk at their preferred speeds on the ground, and surface electromyography (sEMG) and marker trajectory data were collected simultaneously. The gait cycle of each subject was divided into four substages according to the labeled trajectory data. On this basis, fuzzy approximate entropy (fApEn) was used to analyze the complexity of ankle muscle activity during walking. And the transfer entropy (TE) was applied to reflect directed information transmission between ankle muscles. Results found that complexity of ankle muscles activities in patients after stroke showed similar trends to that in healthy subjects. Different from healthy subjects, the complexity of ankle muscle activity in patients with stroke tends to increase in most of the gait sub-phases. While TE values between the ankle muscles in patients with stroke tend to decrease throughout the gait cycle, especially in the second double support stage. Compared with age-matched healthy subjects, patients recruit more motor units throughout their gait while increasing muscle coupling to achieve gait function. The combined application of fApEn and TE provide a more comprehensive understanding of phase-dependent muscle modulation mechanisms in post-stroke patients. |
| format | Article |
| id | doaj-art-bbf4bc182cbd4c278d07a661022c8df2 |
| institution | OA Journals |
| issn | 1534-4320 1558-0210 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | IEEE |
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| series | IEEE Transactions on Neural Systems and Rehabilitation Engineering |
| spelling | doaj-art-bbf4bc182cbd4c278d07a661022c8df22025-08-20T02:25:16ZengIEEEIEEE Transactions on Neural Systems and Rehabilitation Engineering1534-43201558-02102023-01-01311119112710.1109/TNSRE.2023.323875810024397Phase-Dependent Modulation of Muscle Activity and Intermuscular Coupling During Walking in Patients After StrokeYifan Li0Yueling Lyu1Rong Song2https://orcid.org/0000-0003-3662-116XKey Laboratory of Sensing Technology and Biomedical Instrument of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, ChinaKey Laboratory of Sensing Technology and Biomedical Instrument of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, ChinaKey Laboratory of Sensing Technology and Biomedical Instrument of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, ChinaMany patients experience motor and sensory impairments after stroke, leading to gait disturbances. Analysis of muscle modulation mode during walking can provide evidence for neurological changes after stroke, while how stroke affects individual muscle activity and muscular coordination in certain gait sub-phases remains unclear. The purpose of the present study is to comprehensively investigate phase-dependent ankle muscle activity and intermuscular coupling patterns in post-stroke patients. In this experiment, 10 post-stroke patients, 10 young healthy subjects and 10 elderly healthy subjects were recruited. All subjects were asked to walk at their preferred speeds on the ground, and surface electromyography (sEMG) and marker trajectory data were collected simultaneously. The gait cycle of each subject was divided into four substages according to the labeled trajectory data. On this basis, fuzzy approximate entropy (fApEn) was used to analyze the complexity of ankle muscle activity during walking. And the transfer entropy (TE) was applied to reflect directed information transmission between ankle muscles. Results found that complexity of ankle muscles activities in patients after stroke showed similar trends to that in healthy subjects. Different from healthy subjects, the complexity of ankle muscle activity in patients with stroke tends to increase in most of the gait sub-phases. While TE values between the ankle muscles in patients with stroke tend to decrease throughout the gait cycle, especially in the second double support stage. Compared with age-matched healthy subjects, patients recruit more motor units throughout their gait while increasing muscle coupling to achieve gait function. The combined application of fApEn and TE provide a more comprehensive understanding of phase-dependent muscle modulation mechanisms in post-stroke patients.https://ieeexplore.ieee.org/document/10024397/Strokegait phase-dependentmuscle activity complexitymuscular coordination |
| spellingShingle | Yifan Li Yueling Lyu Rong Song Phase-Dependent Modulation of Muscle Activity and Intermuscular Coupling During Walking in Patients After Stroke IEEE Transactions on Neural Systems and Rehabilitation Engineering Stroke gait phase-dependent muscle activity complexity muscular coordination |
| title | Phase-Dependent Modulation of Muscle Activity and Intermuscular Coupling During Walking in Patients After Stroke |
| title_full | Phase-Dependent Modulation of Muscle Activity and Intermuscular Coupling During Walking in Patients After Stroke |
| title_fullStr | Phase-Dependent Modulation of Muscle Activity and Intermuscular Coupling During Walking in Patients After Stroke |
| title_full_unstemmed | Phase-Dependent Modulation of Muscle Activity and Intermuscular Coupling During Walking in Patients After Stroke |
| title_short | Phase-Dependent Modulation of Muscle Activity and Intermuscular Coupling During Walking in Patients After Stroke |
| title_sort | phase dependent modulation of muscle activity and intermuscular coupling during walking in patients after stroke |
| topic | Stroke gait phase-dependent muscle activity complexity muscular coordination |
| url | https://ieeexplore.ieee.org/document/10024397/ |
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