Pilomatricoma on 18F-fluorodeoxyglucose positron emission tomography-computed tomography: Peripheral mimic of an aggressive soft-tissue malignancy
Pilomatricoma, also known as calcifying epithelioma of Malherbe, is a rare skin tumor originating from the hair follicle matrix. We report a case of pilomatricoma in a 50-year-old woman, presenting as a rapidly growing pretibial mass. Malignant pilomatricoma is associated with potentially fatal meta...
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2020-10-01
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| Series: | World Journal of Nuclear Medicine |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.4103/wjnm.WJNM_76_20 |
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| author | Afolarin Otunla Kevin Bradley |
| author_facet | Afolarin Otunla Kevin Bradley |
| author_sort | Afolarin Otunla |
| collection | DOAJ |
| description | Pilomatricoma, also known as calcifying epithelioma of Malherbe, is a rare skin tumor originating from the hair follicle matrix. We report a case of pilomatricoma in a 50-year-old woman, presenting as a rapidly growing pretibial mass. Malignant pilomatricoma is associated with potentially fatal metastases and are clinically and histologically indistinguishable from benign pilomatricoma. Thus, an 18F-fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDG PET/CT) scan was requested for staging, revealing marked FDG uptake restricted to the primary lesion and no evidence of separate disease. The purpose of this report is to demonstrate the importance of PET/CT in the staging of this FDG-avid tumor; the malignancy of which is often first revealed by metastases. Our case also demonstrates that pilomatricoma should be included in the differential diagnosis of a rapidly growing peripheral soft-tissue mass; conventionally, the domain of sarcoma. |
| format | Article |
| id | doaj-art-bbf2cbf2b83a47e892578ead8a5b558e |
| institution | OA Journals |
| issn | 1450-1147 1607-3312 |
| language | English |
| publishDate | 2020-10-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | World Journal of Nuclear Medicine |
| spelling | doaj-art-bbf2cbf2b83a47e892578ead8a5b558e2025-08-20T02:00:24ZengThieme Medical and Scientific Publishers Pvt. Ltd.World Journal of Nuclear Medicine1450-11471607-33122020-10-01190445245410.4103/wjnm.WJNM_76_20Pilomatricoma on 18F-fluorodeoxyglucose positron emission tomography-computed tomography: Peripheral mimic of an aggressive soft-tissue malignancyAfolarin Otunla0Kevin Bradley1Medical Sciences Division, University of Oxford, Oxford, United KingdomWales Research and Diagnostic PET Imaging Centre, University of Cardiff, Oxford, United KingdomPilomatricoma, also known as calcifying epithelioma of Malherbe, is a rare skin tumor originating from the hair follicle matrix. We report a case of pilomatricoma in a 50-year-old woman, presenting as a rapidly growing pretibial mass. Malignant pilomatricoma is associated with potentially fatal metastases and are clinically and histologically indistinguishable from benign pilomatricoma. Thus, an 18F-fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDG PET/CT) scan was requested for staging, revealing marked FDG uptake restricted to the primary lesion and no evidence of separate disease. The purpose of this report is to demonstrate the importance of PET/CT in the staging of this FDG-avid tumor; the malignancy of which is often first revealed by metastases. Our case also demonstrates that pilomatricoma should be included in the differential diagnosis of a rapidly growing peripheral soft-tissue mass; conventionally, the domain of sarcoma.http://www.thieme-connect.de/DOI/DOI?10.4103/wjnm.WJNM_76_20imagingpilomatricomapositron emission tomography-computed tomographysarcoma |
| spellingShingle | Afolarin Otunla Kevin Bradley Pilomatricoma on 18F-fluorodeoxyglucose positron emission tomography-computed tomography: Peripheral mimic of an aggressive soft-tissue malignancy World Journal of Nuclear Medicine imaging pilomatricoma positron emission tomography-computed tomography sarcoma |
| title | Pilomatricoma on 18F-fluorodeoxyglucose positron emission tomography-computed tomography: Peripheral mimic of an aggressive soft-tissue malignancy |
| title_full | Pilomatricoma on 18F-fluorodeoxyglucose positron emission tomography-computed tomography: Peripheral mimic of an aggressive soft-tissue malignancy |
| title_fullStr | Pilomatricoma on 18F-fluorodeoxyglucose positron emission tomography-computed tomography: Peripheral mimic of an aggressive soft-tissue malignancy |
| title_full_unstemmed | Pilomatricoma on 18F-fluorodeoxyglucose positron emission tomography-computed tomography: Peripheral mimic of an aggressive soft-tissue malignancy |
| title_short | Pilomatricoma on 18F-fluorodeoxyglucose positron emission tomography-computed tomography: Peripheral mimic of an aggressive soft-tissue malignancy |
| title_sort | pilomatricoma on 18f fluorodeoxyglucose positron emission tomography computed tomography peripheral mimic of an aggressive soft tissue malignancy |
| topic | imaging pilomatricoma positron emission tomography-computed tomography sarcoma |
| url | http://www.thieme-connect.de/DOI/DOI?10.4103/wjnm.WJNM_76_20 |
| work_keys_str_mv | AT afolarinotunla pilomatricomaon18ffluorodeoxyglucosepositronemissiontomographycomputedtomographyperipheralmimicofanaggressivesofttissuemalignancy AT kevinbradley pilomatricomaon18ffluorodeoxyglucosepositronemissiontomographycomputedtomographyperipheralmimicofanaggressivesofttissuemalignancy |