The relationship between thiamin, folic acid and cognitive function in a rat model of uremia

The relationship between thiamin, folic acid and cognitive function in a rat model of uremia

End-stage renal disease is a worldwide health burden, but the pathogenesis of uremia-associated cognitive impairment (CI) is poorly recognized. We hypothesized that uremia brings about deficiency of thiamin and folic acid and causes CI by inducing oxidative stress. Therefore, 24 Sprague-Dawley rats...

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Bibliographic Details
Main Authors: Yifei Lu, Chenqi Xu, Kewei Xie, Bingru Zhao, Minzhou Wang, Cheng Qian, Xuemei Chen, Leyi Gu, Wangshu Wu, Renhua Lu
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Renal Failure
Subjects:
End-stage renal disease
uremic rat model
cognitive impairment
vitamin B
oxidative stress
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2024.2329257
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