Elevation of plasma podoplanin in Kawasaki disease
Kawasaki disease (KD) is a systemic vasculitis that results in abnormalities in the coronary arteries. Podoplanin (PDPN) and its receptor C-type lectin-like receptor 2 (CLEC-2) are involved in inflammatory hemostasis and have also been proved to be effective predictive markers for early evaluation o...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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De Gruyter
2025-08-01
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| Series: | Journal of Laboratory Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/labmed-2024-0214 |
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| _version_ | 1849390285563363328 |
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| author | Xu Ling Li Wei Geng Zhimin Peng Zhaoyang Sun Anna Qin Wenjun Xie Chunhong Gong Fangqi Shen Hongqiang |
| author_facet | Xu Ling Li Wei Geng Zhimin Peng Zhaoyang Sun Anna Qin Wenjun Xie Chunhong Gong Fangqi Shen Hongqiang |
| author_sort | Xu Ling |
| collection | DOAJ |
| description | Kawasaki disease (KD) is a systemic vasculitis that results in abnormalities in the coronary arteries. Podoplanin (PDPN) and its receptor C-type lectin-like receptor 2 (CLEC-2) are involved in inflammatory hemostasis and have also been proved to be effective predictive markers for early evaluation of sepsis and coagulation. This study aimed to investigate the expression of PDPN and its receptor CLEC-2 in the patients with KD, and evaluate the relationship between PDPN and clinical laboratory parameters. |
| format | Article |
| id | doaj-art-bbcb16a37f304588bc1688df0428c502 |
| institution | Kabale University |
| issn | 2567-9430 2567-9449 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Journal of Laboratory Medicine |
| spelling | doaj-art-bbcb16a37f304588bc1688df0428c5022025-08-20T03:41:43ZengDe GruyterJournal of Laboratory Medicine2567-94302567-94492025-08-0149416316910.1515/labmed-2024-0214Elevation of plasma podoplanin in Kawasaki diseaseXu Ling0Li Wei1Geng Zhimin2Peng Zhaoyang3Sun Anna4Qin Wenjun5Xie Chunhong6Gong Fangqi7Shen Hongqiang8Department of Clinical Laboratory, Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, ChinaDepartment of Clinical Laboratory, Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, ChinaDepartment of Cardiology, Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, ChinaDepartment of Clinical Laboratory, Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, ChinaDepartment of Clinical Laboratory, Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, ChinaDepartment of Pediatric Cardiothoracic Surgery, Shanghai Children’s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Cardiology, Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, ChinaDepartment of Cardiology, Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, ChinaDepartment of Clinical Laboratory, Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, ChinaKawasaki disease (KD) is a systemic vasculitis that results in abnormalities in the coronary arteries. Podoplanin (PDPN) and its receptor C-type lectin-like receptor 2 (CLEC-2) are involved in inflammatory hemostasis and have also been proved to be effective predictive markers for early evaluation of sepsis and coagulation. This study aimed to investigate the expression of PDPN and its receptor CLEC-2 in the patients with KD, and evaluate the relationship between PDPN and clinical laboratory parameters.https://doi.org/10.1515/labmed-2024-0214coronary artery lesionscoagulationkawasaki diseaseinflammation indicatorspdpn |
| spellingShingle | Xu Ling Li Wei Geng Zhimin Peng Zhaoyang Sun Anna Qin Wenjun Xie Chunhong Gong Fangqi Shen Hongqiang Elevation of plasma podoplanin in Kawasaki disease Journal of Laboratory Medicine coronary artery lesions coagulation kawasaki disease inflammation indicators pdpn |
| title | Elevation of plasma podoplanin in Kawasaki disease |
| title_full | Elevation of plasma podoplanin in Kawasaki disease |
| title_fullStr | Elevation of plasma podoplanin in Kawasaki disease |
| title_full_unstemmed | Elevation of plasma podoplanin in Kawasaki disease |
| title_short | Elevation of plasma podoplanin in Kawasaki disease |
| title_sort | elevation of plasma podoplanin in kawasaki disease |
| topic | coronary artery lesions coagulation kawasaki disease inflammation indicators pdpn |
| url | https://doi.org/10.1515/labmed-2024-0214 |
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