Elevation of plasma podoplanin in Kawasaki disease

Kawasaki disease (KD) is a systemic vasculitis that results in abnormalities in the coronary arteries. Podoplanin (PDPN) and its receptor C-type lectin-like receptor 2 (CLEC-2) are involved in inflammatory hemostasis and have also been proved to be effective predictive markers for early evaluation o...

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Bibliographic Details
Main Authors: Xu Ling, Li Wei, Geng Zhimin, Peng Zhaoyang, Sun Anna, Qin Wenjun, Xie Chunhong, Gong Fangqi, Shen Hongqiang
Format: Article
Language:English
Published: De Gruyter 2025-08-01
Series:Journal of Laboratory Medicine
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Online Access:https://doi.org/10.1515/labmed-2024-0214
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Summary:Kawasaki disease (KD) is a systemic vasculitis that results in abnormalities in the coronary arteries. Podoplanin (PDPN) and its receptor C-type lectin-like receptor 2 (CLEC-2) are involved in inflammatory hemostasis and have also been proved to be effective predictive markers for early evaluation of sepsis and coagulation. This study aimed to investigate the expression of PDPN and its receptor CLEC-2 in the patients with KD, and evaluate the relationship between PDPN and clinical laboratory parameters.
ISSN:2567-9430
2567-9449