The Pattern of Juvenile Idiopathic Arthritis in a Single Tertiary Center in Saudi Arabia

Introduction. Juvenile Idiopathic Arthritis (JIA) is the most common chronic arthritis in children. Our aim is to describe demographic, clinical, and laboratory characteristics and treatment of JIA patients followed up in Pediatric Rheumatology clinic in a tertiary center in Saudi Arabia. Methods. M...

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Main Authors: Mohammad H. Al-Hemairi, Shatha M. Albokhari, Mohammed A. Muzaffer
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:International Journal of Inflammation
Online Access:http://dx.doi.org/10.1155/2016/7802957
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author Mohammad H. Al-Hemairi
Shatha M. Albokhari
Mohammed A. Muzaffer
author_facet Mohammad H. Al-Hemairi
Shatha M. Albokhari
Mohammed A. Muzaffer
author_sort Mohammad H. Al-Hemairi
collection DOAJ
description Introduction. Juvenile Idiopathic Arthritis (JIA) is the most common chronic arthritis in children. Our aim is to describe demographic, clinical, and laboratory characteristics and treatment of JIA patients followed up in Pediatric Rheumatology clinic in a tertiary center in Saudi Arabia. Methods. Medical records of all patients who are followed up between January 2007 and January 2015 were retrospectively reviewed. Data were collected about demographic, clinical, and laboratory features and treatment. Results. Total patients were 82, males were 31 (37.8%), and mean age of JIA onset was 7.1 ± 3.6 yr. Mean follow-up duration was 2.67±1.6 yr. Systemic onset JIA (SoJIA) was the commonest (36.5%), followed by polyarticular in 29.2% and oligoarticular in 28%. Large and small joints are involved in 76 (92%) and 30 (36.6%), respectively. Main extra-articular feature was fever in 34 (41.4%). Uveitis was diagnosed in 7 (8.5%) and in 5 (21.7%) of oligoarticular JIA. Anemia was found in 49 (59.7%), high ESR in 45 (54.8%), and leukocytosis and thrombocytosis in 33 (40.2%). Positive ANA was found in 30 (36.5%) mainly in oligoarticular subtype as 12 (52%) patients (out of 23) had this positive test. 9 patients (10.9%) required NSAIDs only, 6 patients (7.3%) required NSAIDs and intra-articular steroids only, and 19 (23%) required NSAIDs, methotrexate, steroids, and biologics. Conclusion. SoJIA is the most common JIA subtype in our study. A population based rather than a single center study will give more details about JIA characteristics in Saudi Arabia
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spelling doaj-art-bbcacbcc7aea4650afbb396093a52b732025-08-20T02:18:42ZengWileyInternational Journal of Inflammation2090-80402042-00992016-01-01201610.1155/2016/78029577802957The Pattern of Juvenile Idiopathic Arthritis in a Single Tertiary Center in Saudi ArabiaMohammad H. Al-Hemairi0Shatha M. Albokhari1Mohammed A. Muzaffer2Department of General Pediatrics, Rabigh General Hospital, P.O. Box 51, Rabigh 21911, Saudi ArabiaDepartment of Pediatrics, Division of Pediatric Rheumatology, King Abdulaziz University Hospital, P.O. Box. 80218, Jeddah 21589, Saudi ArabiaDepartment of Pediatrics, Division of Pediatric Rheumatology, King Abdulaziz University Hospital, P.O. Box. 80218, Jeddah 21589, Saudi ArabiaIntroduction. Juvenile Idiopathic Arthritis (JIA) is the most common chronic arthritis in children. Our aim is to describe demographic, clinical, and laboratory characteristics and treatment of JIA patients followed up in Pediatric Rheumatology clinic in a tertiary center in Saudi Arabia. Methods. Medical records of all patients who are followed up between January 2007 and January 2015 were retrospectively reviewed. Data were collected about demographic, clinical, and laboratory features and treatment. Results. Total patients were 82, males were 31 (37.8%), and mean age of JIA onset was 7.1 ± 3.6 yr. Mean follow-up duration was 2.67±1.6 yr. Systemic onset JIA (SoJIA) was the commonest (36.5%), followed by polyarticular in 29.2% and oligoarticular in 28%. Large and small joints are involved in 76 (92%) and 30 (36.6%), respectively. Main extra-articular feature was fever in 34 (41.4%). Uveitis was diagnosed in 7 (8.5%) and in 5 (21.7%) of oligoarticular JIA. Anemia was found in 49 (59.7%), high ESR in 45 (54.8%), and leukocytosis and thrombocytosis in 33 (40.2%). Positive ANA was found in 30 (36.5%) mainly in oligoarticular subtype as 12 (52%) patients (out of 23) had this positive test. 9 patients (10.9%) required NSAIDs only, 6 patients (7.3%) required NSAIDs and intra-articular steroids only, and 19 (23%) required NSAIDs, methotrexate, steroids, and biologics. Conclusion. SoJIA is the most common JIA subtype in our study. A population based rather than a single center study will give more details about JIA characteristics in Saudi Arabiahttp://dx.doi.org/10.1155/2016/7802957
spellingShingle Mohammad H. Al-Hemairi
Shatha M. Albokhari
Mohammed A. Muzaffer
The Pattern of Juvenile Idiopathic Arthritis in a Single Tertiary Center in Saudi Arabia
International Journal of Inflammation
title The Pattern of Juvenile Idiopathic Arthritis in a Single Tertiary Center in Saudi Arabia
title_full The Pattern of Juvenile Idiopathic Arthritis in a Single Tertiary Center in Saudi Arabia
title_fullStr The Pattern of Juvenile Idiopathic Arthritis in a Single Tertiary Center in Saudi Arabia
title_full_unstemmed The Pattern of Juvenile Idiopathic Arthritis in a Single Tertiary Center in Saudi Arabia
title_short The Pattern of Juvenile Idiopathic Arthritis in a Single Tertiary Center in Saudi Arabia
title_sort pattern of juvenile idiopathic arthritis in a single tertiary center in saudi arabia
url http://dx.doi.org/10.1155/2016/7802957
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