Effects of bariatric surgery upon the sympathetic nervous system and hypothalamic-pituitary-adrenal axis in obese humans

Effects of bariatric surgery upon the sympathetic nervous system and hypothalamic-pituitary-adrenal axis in obese humans

Abstract Human obesity is a state of hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis and dysfunction of the sympathetic nervous system (SNS). It is unclear whether weight loss will normalize this apparent dysfunction and if potential changes are of short -or long-term duration. In thi...

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Bibliographic Details
Main Authors: Andreas Kraag Ziegler, Mette Christensen, Henrik Løvendahl Jørgensen, Mogens Fenger, Sara Fogh Myrup, Carsten Dirksen, Sten Madsbad
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Gastric bypass
Bariatric surgery
Roux-en-Y Gastric Bypass
Weight loss
Autonomous nervous system
HPA-axis
Online Access:https://doi.org/10.1038/s41598-025-14537-4
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