Venous Thromboembolism in Spinal Fusion Surgery: A Literature Review of Economic Impact, Risk Factors, and Preoperative Management
Study Design: Literature Review Objectives: To conduct a comprehensive literature review about the risk factors and preoperative considerations that are related to postoperative venous thromboembolisms (VTEs) in patients who undergo spinal fusion. Results: Postoperative VTEs are associated with high...
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| Format: | Article |
| Language: | English |
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The Japanese Society for Spine Surgery and Related Research
2025-03-01
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| Series: | Spine Surgery and Related Research |
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| Online Access: | https://www.jstage.jst.go.jp/article/ssrr/9/2/9_2024-0220/_pdf/-char/en |
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| _version_ | 1849731187907493888 |
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| author | Sai Suraj Kollapaneni Malek Moumne Henry Twibell John DeVine |
| author_facet | Sai Suraj Kollapaneni Malek Moumne Henry Twibell John DeVine |
| author_sort | Sai Suraj Kollapaneni |
| collection | DOAJ |
| description | Study Design: Literature Review
Objectives: To conduct a comprehensive literature review about the risk factors and preoperative considerations that are related to postoperative venous thromboembolisms (VTEs) in patients who undergo spinal fusion.
Results: Postoperative VTEs are associated with higher costs and longer hospital stays for patients, in comparison to those who did not develop VTEs. Spinal level and multilevel fusion are risk factors for postoperative VTE. The effect of the surgical approach on VTE risk is unclear. Elevated BMI and age, kidney dysfunction, previous VTE, and primary hypercoagulability are preoperative risk factors for developing VTE. Intraoperative and postoperative risk factors for VTE include prolonged procedure time, discharge to inpatient facilities, and length of hospital stay. The effects of hypertension (HTN), sex, and dural tears on VTE risk in spinal fusion patients are uncertain. Chemoprophylaxis reduced the incidence of VTE. Tranexamic acid was not associated with an increase in VTE postoperatively. The American College of Surgeons National Surgical Quality Improvement Program surgical risk calculator served as a poor predictor of VTE incidence in spinal fusion. Preoperative D-dimer levels may help as a predictive tool.
Conclusions: To elucidate the effects of surgical approach, revision surgery, HTN, and dural tears on postoperative VTE risk, further research is warranted. To help identify high-risk patients, a risk calculator sensitive to VTE must be developed. |
| format | Article |
| id | doaj-art-bbb893b4e36e4d818b3dfaf1bf215d6e |
| institution | DOAJ |
| issn | 2432-261X |
| language | English |
| publishDate | 2025-03-01 |
| publisher | The Japanese Society for Spine Surgery and Related Research |
| record_format | Article |
| series | Spine Surgery and Related Research |
| spelling | doaj-art-bbb893b4e36e4d818b3dfaf1bf215d6e2025-08-20T03:08:37ZengThe Japanese Society for Spine Surgery and Related ResearchSpine Surgery and Related Research2432-261X2025-03-019211211910.22603/ssrr.2024-02202024-0220Venous Thromboembolism in Spinal Fusion Surgery: A Literature Review of Economic Impact, Risk Factors, and Preoperative ManagementSai Suraj Kollapaneni0Malek Moumne1Henry Twibell2John DeVine3Department of Orthopaedic Surgery, Wellstar MCG Health, Medical College of Georgia, AugustaDepartment of Orthopaedic Surgery, Wellstar MCG Health, Medical College of Georgia, AugustaDepartment of Orthopaedic Surgery, Wellstar MCG Health, Medical College of Georgia, AugustaDepartment of Orthopaedic Surgery, Wellstar MCG Health, Medical College of Georgia, AugustaStudy Design: Literature Review Objectives: To conduct a comprehensive literature review about the risk factors and preoperative considerations that are related to postoperative venous thromboembolisms (VTEs) in patients who undergo spinal fusion. Results: Postoperative VTEs are associated with higher costs and longer hospital stays for patients, in comparison to those who did not develop VTEs. Spinal level and multilevel fusion are risk factors for postoperative VTE. The effect of the surgical approach on VTE risk is unclear. Elevated BMI and age, kidney dysfunction, previous VTE, and primary hypercoagulability are preoperative risk factors for developing VTE. Intraoperative and postoperative risk factors for VTE include prolonged procedure time, discharge to inpatient facilities, and length of hospital stay. The effects of hypertension (HTN), sex, and dural tears on VTE risk in spinal fusion patients are uncertain. Chemoprophylaxis reduced the incidence of VTE. Tranexamic acid was not associated with an increase in VTE postoperatively. The American College of Surgeons National Surgical Quality Improvement Program surgical risk calculator served as a poor predictor of VTE incidence in spinal fusion. Preoperative D-dimer levels may help as a predictive tool. Conclusions: To elucidate the effects of surgical approach, revision surgery, HTN, and dural tears on postoperative VTE risk, further research is warranted. To help identify high-risk patients, a risk calculator sensitive to VTE must be developed.https://www.jstage.jst.go.jp/article/ssrr/9/2/9_2024-0220/_pdf/-char/enthromboembolismrisk factorsoutcomesspinal fusioneconomic impactprevention |
| spellingShingle | Sai Suraj Kollapaneni Malek Moumne Henry Twibell John DeVine Venous Thromboembolism in Spinal Fusion Surgery: A Literature Review of Economic Impact, Risk Factors, and Preoperative Management Spine Surgery and Related Research thromboembolism risk factors outcomes spinal fusion economic impact prevention |
| title | Venous Thromboembolism in Spinal Fusion Surgery: A Literature Review of Economic Impact, Risk Factors, and Preoperative Management |
| title_full | Venous Thromboembolism in Spinal Fusion Surgery: A Literature Review of Economic Impact, Risk Factors, and Preoperative Management |
| title_fullStr | Venous Thromboembolism in Spinal Fusion Surgery: A Literature Review of Economic Impact, Risk Factors, and Preoperative Management |
| title_full_unstemmed | Venous Thromboembolism in Spinal Fusion Surgery: A Literature Review of Economic Impact, Risk Factors, and Preoperative Management |
| title_short | Venous Thromboembolism in Spinal Fusion Surgery: A Literature Review of Economic Impact, Risk Factors, and Preoperative Management |
| title_sort | venous thromboembolism in spinal fusion surgery a literature review of economic impact risk factors and preoperative management |
| topic | thromboembolism risk factors outcomes spinal fusion economic impact prevention |
| url | https://www.jstage.jst.go.jp/article/ssrr/9/2/9_2024-0220/_pdf/-char/en |
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