Role of Emollients in Prevention of the Comorbid Allergic Diseases Development in Children with Atopic Dermatitis
Atopic dermatitis (AD) is one of the common multifactorial inflammatory diseases manifesting predominantly in childhood. There is significant number of cases of self-regression of the disease with aging. On the other hand, there is also another scenario ending with AD persistent course and/or develo...
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| Format: | Article |
| Language: | Russian |
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Union of pediatricians of Russia
2020-09-01
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| Series: | Педиатрическая фармакология |
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| Online Access: | https://www.pedpharma.ru/jour/article/view/1885 |
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| author | Nikolay N. Murashkin Roman A. Ivanov Dmitri V. Fedorov Eduard T. Ambarchyan Roman V. Epishev Alexander I. Materikin Leonid A. Opryatin Alena A. Savelova |
| author_facet | Nikolay N. Murashkin Roman A. Ivanov Dmitri V. Fedorov Eduard T. Ambarchyan Roman V. Epishev Alexander I. Materikin Leonid A. Opryatin Alena A. Savelova |
| author_sort | Nikolay N. Murashkin |
| collection | DOAJ |
| description | Atopic dermatitis (AD) is one of the common multifactorial inflammatory diseases manifesting predominantly in childhood. There is significant number of cases of self-regression of the disease with aging. On the other hand, there is also another scenario ending with AD persistent course and/or development of comorbid allergic pathologies that can significantly worsen patient’s quality of life and finally lead to social maladjustment. The pathogenesis of such way includes epidermal barrier disturbance, transcutaneous sensibilisation and aberrant allergic (Th2) immune systemic response development. Main role in preventing of this pathological pathway is lying on the new class of moisturizers containing active components "emollients plus". They are considered as foundation for the therapy and prevention of the development of AD and other allergic diseases. This literature review provides relevant data on AD pathogenesis and development of comorbid allergic pathologies. This paper also covers data on the effect of emollients in restoration of the epidermal barrier and their use as preventive measures. |
| format | Article |
| id | doaj-art-bbb4bc391cd743978f51acf0697dae5b |
| institution | Kabale University |
| issn | 1727-5776 2500-3089 |
| language | Russian |
| publishDate | 2020-09-01 |
| publisher | Union of pediatricians of Russia |
| record_format | Article |
| series | Педиатрическая фармакология |
| spelling | doaj-art-bbb4bc391cd743978f51acf0697dae5b2025-08-20T03:39:29ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892020-09-0117433433910.15690/pf.v17i4.21601731Role of Emollients in Prevention of the Comorbid Allergic Diseases Development in Children with Atopic DermatitisNikolay N. Murashkin0Roman A. Ivanov1Dmitri V. Fedorov2Eduard T. Ambarchyan3Roman V. Epishev4Alexander I. Materikin5Leonid A. Opryatin6Alena A. Savelova7National Medical Research Center of Children’s Health; Sechenov First Moscow State Medical University; Central State Medical Academy of Department of Presidential Affairs; Research Institute of Pediatrics and Children’s Health in «Central Clinical Hospital of the Russian Academy of Sciences»National Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthAtopic dermatitis (AD) is one of the common multifactorial inflammatory diseases manifesting predominantly in childhood. There is significant number of cases of self-regression of the disease with aging. On the other hand, there is also another scenario ending with AD persistent course and/or development of comorbid allergic pathologies that can significantly worsen patient’s quality of life and finally lead to social maladjustment. The pathogenesis of such way includes epidermal barrier disturbance, transcutaneous sensibilisation and aberrant allergic (Th2) immune systemic response development. Main role in preventing of this pathological pathway is lying on the new class of moisturizers containing active components "emollients plus". They are considered as foundation for the therapy and prevention of the development of AD and other allergic diseases. This literature review provides relevant data on AD pathogenesis and development of comorbid allergic pathologies. This paper also covers data on the effect of emollients in restoration of the epidermal barrier and their use as preventive measures.https://www.pedpharma.ru/jour/article/view/1885atopic dermatitisepidermal barrieratopic marchemollients |
| spellingShingle | Nikolay N. Murashkin Roman A. Ivanov Dmitri V. Fedorov Eduard T. Ambarchyan Roman V. Epishev Alexander I. Materikin Leonid A. Opryatin Alena A. Savelova Role of Emollients in Prevention of the Comorbid Allergic Diseases Development in Children with Atopic Dermatitis Педиатрическая фармакология atopic dermatitis epidermal barrier atopic march emollients |
| title | Role of Emollients in Prevention of the Comorbid Allergic Diseases Development in Children with Atopic Dermatitis |
| title_full | Role of Emollients in Prevention of the Comorbid Allergic Diseases Development in Children with Atopic Dermatitis |
| title_fullStr | Role of Emollients in Prevention of the Comorbid Allergic Diseases Development in Children with Atopic Dermatitis |
| title_full_unstemmed | Role of Emollients in Prevention of the Comorbid Allergic Diseases Development in Children with Atopic Dermatitis |
| title_short | Role of Emollients in Prevention of the Comorbid Allergic Diseases Development in Children with Atopic Dermatitis |
| title_sort | role of emollients in prevention of the comorbid allergic diseases development in children with atopic dermatitis |
| topic | atopic dermatitis epidermal barrier atopic march emollients |
| url | https://www.pedpharma.ru/jour/article/view/1885 |
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