Tolerability study of Imidacloprid-Pyriproxyfen-Moxidectin-based drugs in dogs and cats
The purpose of the research is to study tolerance of Imidacloprid-Pyriproxyfen-Moxidectin-based drugs for veterinary use by target animal species.Materials and methods. The research was conducted on 15 clinically healthy outbred cats aged 1–2 years weighing 3–5 kg, 15 clinically healthy outbred kitt...
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| Format: | Article |
| Language: | Russian |
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Federal Scientific Centre VIEV
2023-01-01
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| Series: | Российский паразитологический журнал |
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| Online Access: | https://vniigis.elpub.ru/jour/article/view/970 |
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| author | O. N. Tochieva M. V. Arisov |
| author_facet | O. N. Tochieva M. V. Arisov |
| author_sort | O. N. Tochieva |
| collection | DOAJ |
| description | The purpose of the research is to study tolerance of Imidacloprid-Pyriproxyfen-Moxidectin-based drugs for veterinary use by target animal species.Materials and methods. The research was conducted on 15 clinically healthy outbred cats aged 1–2 years weighing 3–5 kg, 15 clinically healthy outbred kittens aged 7–9 weeks weighing 700–900 g, 15 clinically healthy outbred dogs aged 1–2 years weighing 18–20 kg, and 15 clinically healthy outbred puppies aged 7 weeks up to three months weighing 6–9 kg, in the Kurilovo Experimental Base, the Podolsk Department of the VNIIP – FSC VIEV, in 2021. Combined drugs, Insacar Total S and Insacar Total K (Imidacloprid, Pyriproxyfen and Moxidectin), were used as drips, which was resulted in good absorption of active substances through the skin. The effect of combined Imidacloprid-Pyriproxyfen-Moxidectin-based drugs was evaluated on general condition and behavior, body weight gain dynamics, animal morphological and biochemical blood parameters, and physicochemical urine parameters.Results and discussion. Drugs for veterinary use, Insacar Total K and Insacar Total S, in increased therapeutic doses (twice and five-fold) do not adversely affect the general condition and behavior of cats, kittens, dogs or puppies; no deviations were recorded in morphological and biochemical blood parameters, or physicochemical urine parameters. |
| format | Article |
| id | doaj-art-bbb0fb019bb648ed957ce74fa4e29273 |
| institution | Kabale University |
| issn | 1998-8435 2541-7843 |
| language | Russian |
| publishDate | 2023-01-01 |
| publisher | Federal Scientific Centre VIEV |
| record_format | Article |
| series | Российский паразитологический журнал |
| spelling | doaj-art-bbb0fb019bb648ed957ce74fa4e292732025-08-20T03:59:17ZrusFederal Scientific Centre VIEVРоссийский паразитологический журнал1998-84352541-78432023-01-0116443944910.31016/1998-8435-2022-16-4-439-449717Tolerability study of Imidacloprid-Pyriproxyfen-Moxidectin-based drugs in dogs and catsO. N. Tochieva0M. V. Arisov1Russian State Center for Animal Feed and Drug Standardization and Quality (FGBU “VGNKI”)All-Russian Scientific Research Institute for Fundamental and Applied Parasitology of Animals and Plant – a branch of the Federal State Budget Scientific Institution "Federal Scientific Centre VIEV"The purpose of the research is to study tolerance of Imidacloprid-Pyriproxyfen-Moxidectin-based drugs for veterinary use by target animal species.Materials and methods. The research was conducted on 15 clinically healthy outbred cats aged 1–2 years weighing 3–5 kg, 15 clinically healthy outbred kittens aged 7–9 weeks weighing 700–900 g, 15 clinically healthy outbred dogs aged 1–2 years weighing 18–20 kg, and 15 clinically healthy outbred puppies aged 7 weeks up to three months weighing 6–9 kg, in the Kurilovo Experimental Base, the Podolsk Department of the VNIIP – FSC VIEV, in 2021. Combined drugs, Insacar Total S and Insacar Total K (Imidacloprid, Pyriproxyfen and Moxidectin), were used as drips, which was resulted in good absorption of active substances through the skin. The effect of combined Imidacloprid-Pyriproxyfen-Moxidectin-based drugs was evaluated on general condition and behavior, body weight gain dynamics, animal morphological and biochemical blood parameters, and physicochemical urine parameters.Results and discussion. Drugs for veterinary use, Insacar Total K and Insacar Total S, in increased therapeutic doses (twice and five-fold) do not adversely affect the general condition and behavior of cats, kittens, dogs or puppies; no deviations were recorded in morphological and biochemical blood parameters, or physicochemical urine parameters.https://vniigis.elpub.ru/jour/article/view/970imidaclopridpyriproxyfenmoxidectininsacar total sinsacar total ktolerancedogscats |
| spellingShingle | O. N. Tochieva M. V. Arisov Tolerability study of Imidacloprid-Pyriproxyfen-Moxidectin-based drugs in dogs and cats Российский паразитологический журнал imidacloprid pyriproxyfen moxidectin insacar total s insacar total k tolerance dogs cats |
| title | Tolerability study of Imidacloprid-Pyriproxyfen-Moxidectin-based drugs in dogs and cats |
| title_full | Tolerability study of Imidacloprid-Pyriproxyfen-Moxidectin-based drugs in dogs and cats |
| title_fullStr | Tolerability study of Imidacloprid-Pyriproxyfen-Moxidectin-based drugs in dogs and cats |
| title_full_unstemmed | Tolerability study of Imidacloprid-Pyriproxyfen-Moxidectin-based drugs in dogs and cats |
| title_short | Tolerability study of Imidacloprid-Pyriproxyfen-Moxidectin-based drugs in dogs and cats |
| title_sort | tolerability study of imidacloprid pyriproxyfen moxidectin based drugs in dogs and cats |
| topic | imidacloprid pyriproxyfen moxidectin insacar total s insacar total k tolerance dogs cats |
| url | https://vniigis.elpub.ru/jour/article/view/970 |
| work_keys_str_mv | AT ontochieva tolerabilitystudyofimidaclopridpyriproxyfenmoxidectinbaseddrugsindogsandcats AT mvarisov tolerabilitystudyofimidaclopridpyriproxyfenmoxidectinbaseddrugsindogsandcats |