Multi-omics analysis reveals glutathione metabolism-related immune suppression and constructs a prognostic model in lung adenocarcinoma

Multi-omics analysis reveals glutathione metabolism-related immune suppression and constructs a prognostic model in lung adenocarcinoma

BackgroundMetabolic reprogramming within the tumor microenvironment plays a pivotal role in tumor progression and therapeutic responses. Nevertheless, the relationship between aberrant glutathione (GSH) metabolism and the immune microenvironment in lung adenocarcinoma, as well as its clinical implic...

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Bibliographic Details
Main Authors: Yuxiang Chi, Guoyuan Ma, Qiang Liu, Yunzhi Xiang, Defeng Liu, Jiajun Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
multi-omics
single-cell sequencing
glutathione metabolism
immunotherapy
prognostic model
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1608407/full
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