Morphological, Physiological, Biochemical, and Molecular Characterization of Fungal Species Associated with Papaya Rot in Cameroon

Post-harvest decay of <i>Carica papaya</i> L. is the primary cause of deterioration in papaya quality and the low economic impact of this sector in Cameroon. Field surveys conducted by teams from the Ministry of Agriculture and Rural Development (MINADER) in Cameroon have primarily assoc...

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Main Authors: Moussango Victor Davy, Voundi Olugu Steve, Tchabong Raymond Sammuel, Marie Ampères Bedine Boat, Ntah Ayong Moise, Anna Cazanevscaia Busuioc, Priscile Ebong Mbondi, Andreea Veronica Dediu Botezatu, Manz Koule Jules, Maria Daniela Ionica Mihaila, Rodica Mihaela Dinica, Sameza Modeste Lambert
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Journal of Fungi
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Online Access:https://www.mdpi.com/2309-608X/11/5/385
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author Moussango Victor Davy
Voundi Olugu Steve
Tchabong Raymond Sammuel
Marie Ampères Bedine Boat
Ntah Ayong Moise
Anna Cazanevscaia Busuioc
Priscile Ebong Mbondi
Andreea Veronica Dediu Botezatu
Manz Koule Jules
Maria Daniela Ionica Mihaila
Rodica Mihaela Dinica
Sameza Modeste Lambert
author_facet Moussango Victor Davy
Voundi Olugu Steve
Tchabong Raymond Sammuel
Marie Ampères Bedine Boat
Ntah Ayong Moise
Anna Cazanevscaia Busuioc
Priscile Ebong Mbondi
Andreea Veronica Dediu Botezatu
Manz Koule Jules
Maria Daniela Ionica Mihaila
Rodica Mihaela Dinica
Sameza Modeste Lambert
author_sort Moussango Victor Davy
collection DOAJ
description Post-harvest decay of <i>Carica papaya</i> L. is the primary cause of deterioration in papaya quality and the low economic impact of this sector in Cameroon. Field surveys conducted by teams from the Ministry of Agriculture and Rural Development (MINADER) in Cameroon have primarily associated these decays with fungal attacks. However, to date, no methodological analysis has been conducted on the identification of these fungal agents. To reduce post-harvest losses, rapid detection of diseases is crucial for the application of effective management strategies. This study sought to identify the fungal agents associated with post-harvest decay of papaya <i>cv</i> Sunrise solo in Cameroon and to determine their physiological and biochemical growth characteristics. Isolation and pathogenicity tests were performed according to Koch’s postulate. Molecular identification of isolates was achieved by amplification and sequencing of the ITS1 and ITS4 regions. Phylogenetic analysis was based on the substitution models corresponding to each fungal genus determined by jModeltest, according to the Akaike information criterion (AIC). Fungal explants of each identified species were subjected to variations in temperature, pH, water activity, and NaCl concentration. The ability to secrete hydrolytic enzymes was determined on specific media such as skimmed milk agar for protease, peptone agar for lipase, and carboxymethylcellulose for cellulase. These experiments allowed the identification of three fungi responsible for papaya fruit decay, namely <i>Colletotrichum gloeosporioides</i>, <i>Fusarium equiseti</i>, and <i>Lasiodiplodia theobromae</i>. All three pathogens had maximum mycelial growth at a temperature of 25 ± 2 °C, pH 6.5, NaCl concentration of 100 µM, and water activity (aw) equal to 0.98. The three fungal agents demonstrated a strong potential for secreting cellulases, lipases, and proteases, which they use as lytic enzymes to degrade papaya tissues. The relative enzymatic activity varied depending on the fungal pathogen as well as the type of enzyme secreted. This study is the first report of <i>F. equiseti</i> as a causal agent of papaya fruit decay in Cameroon.
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spelling doaj-art-bb97ad53e4b7407387026cfc17dd71a42025-08-20T01:56:16ZengMDPI AGJournal of Fungi2309-608X2025-05-0111538510.3390/jof11050385Morphological, Physiological, Biochemical, and Molecular Characterization of Fungal Species Associated with Papaya Rot in CameroonMoussango Victor Davy0Voundi Olugu Steve1Tchabong Raymond Sammuel2Marie Ampères Bedine Boat3Ntah Ayong Moise4Anna Cazanevscaia Busuioc5Priscile Ebong Mbondi6Andreea Veronica Dediu Botezatu7Manz Koule Jules8Maria Daniela Ionica Mihaila9Rodica Mihaela Dinica10Sameza Modeste Lambert11Biotechnologies Laboratory, University Institute of Technology, University of Douala, Douala 8698, CameroonBiotechnologies Laboratory, University Institute of Technology, University of Douala, Douala 8698, CameroonDepartment of Processing and Quality Control of Aquatic Products, Institute of Fisheries and Aquatic Sciences, University of Douala, Douala 7236, CameroonPhytopathology and Agricultural Zoology Research Unit, Faculty of Agronomy and Agronomic Sciences, University of Dschang, Dschang 67, CameroonLaboratory of Biochemistry, Faculty of Science, University of Douala, Douala 24157, CameroonDepartment of Chemistry, Physics and Environment, Faculty of Sciences and Environment, ‘Dunărea de Jos’ University, 47 Domneasca Str., 800008 Galati, RomaniaLaboratory of Biochemistry, Faculty of Science, University of Douala, Douala 24157, CameroonDepartment of Chemistry, Physics and Environment, Faculty of Sciences and Environment, ‘Dunărea de Jos’ University, 47 Domneasca Str., 800008 Galati, RomaniaLaboratory of Biochemistry, Faculty of Science, University of Douala, Douala 24157, CameroonDepartment of Chemistry, Physics and Environment, Faculty of Sciences and Environment, ‘Dunărea de Jos’ University, 47 Domneasca Str., 800008 Galati, RomaniaDepartment of Chemistry, Physics and Environment, Faculty of Sciences and Environment, ‘Dunărea de Jos’ University, 47 Domneasca Str., 800008 Galati, RomaniaLaboratory of Biochemistry, Faculty of Science, University of Douala, Douala 24157, CameroonPost-harvest decay of <i>Carica papaya</i> L. is the primary cause of deterioration in papaya quality and the low economic impact of this sector in Cameroon. Field surveys conducted by teams from the Ministry of Agriculture and Rural Development (MINADER) in Cameroon have primarily associated these decays with fungal attacks. However, to date, no methodological analysis has been conducted on the identification of these fungal agents. To reduce post-harvest losses, rapid detection of diseases is crucial for the application of effective management strategies. This study sought to identify the fungal agents associated with post-harvest decay of papaya <i>cv</i> Sunrise solo in Cameroon and to determine their physiological and biochemical growth characteristics. Isolation and pathogenicity tests were performed according to Koch’s postulate. Molecular identification of isolates was achieved by amplification and sequencing of the ITS1 and ITS4 regions. Phylogenetic analysis was based on the substitution models corresponding to each fungal genus determined by jModeltest, according to the Akaike information criterion (AIC). Fungal explants of each identified species were subjected to variations in temperature, pH, water activity, and NaCl concentration. The ability to secrete hydrolytic enzymes was determined on specific media such as skimmed milk agar for protease, peptone agar for lipase, and carboxymethylcellulose for cellulase. These experiments allowed the identification of three fungi responsible for papaya fruit decay, namely <i>Colletotrichum gloeosporioides</i>, <i>Fusarium equiseti</i>, and <i>Lasiodiplodia theobromae</i>. All three pathogens had maximum mycelial growth at a temperature of 25 ± 2 °C, pH 6.5, NaCl concentration of 100 µM, and water activity (aw) equal to 0.98. The three fungal agents demonstrated a strong potential for secreting cellulases, lipases, and proteases, which they use as lytic enzymes to degrade papaya tissues. The relative enzymatic activity varied depending on the fungal pathogen as well as the type of enzyme secreted. This study is the first report of <i>F. equiseti</i> as a causal agent of papaya fruit decay in Cameroon.https://www.mdpi.com/2309-608X/11/5/385<i>Carica papaya</i> rotfungi characterizationphylogenetic analysispathogenicityhydrolytic enzymes
spellingShingle Moussango Victor Davy
Voundi Olugu Steve
Tchabong Raymond Sammuel
Marie Ampères Bedine Boat
Ntah Ayong Moise
Anna Cazanevscaia Busuioc
Priscile Ebong Mbondi
Andreea Veronica Dediu Botezatu
Manz Koule Jules
Maria Daniela Ionica Mihaila
Rodica Mihaela Dinica
Sameza Modeste Lambert
Morphological, Physiological, Biochemical, and Molecular Characterization of Fungal Species Associated with Papaya Rot in Cameroon
Journal of Fungi
<i>Carica papaya</i> rot
fungi characterization
phylogenetic analysis
pathogenicity
hydrolytic enzymes
title Morphological, Physiological, Biochemical, and Molecular Characterization of Fungal Species Associated with Papaya Rot in Cameroon
title_full Morphological, Physiological, Biochemical, and Molecular Characterization of Fungal Species Associated with Papaya Rot in Cameroon
title_fullStr Morphological, Physiological, Biochemical, and Molecular Characterization of Fungal Species Associated with Papaya Rot in Cameroon
title_full_unstemmed Morphological, Physiological, Biochemical, and Molecular Characterization of Fungal Species Associated with Papaya Rot in Cameroon
title_short Morphological, Physiological, Biochemical, and Molecular Characterization of Fungal Species Associated with Papaya Rot in Cameroon
title_sort morphological physiological biochemical and molecular characterization of fungal species associated with papaya rot in cameroon
topic <i>Carica papaya</i> rot
fungi characterization
phylogenetic analysis
pathogenicity
hydrolytic enzymes
url https://www.mdpi.com/2309-608X/11/5/385
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