Fabrication of silver-containing antibacterial coating on titanium by alkaline-heat treatment and hydrothermal sterilization

In this study, a silver-modified layer was prepared on pure titanium through alkaline-heat treatment followed by hydrothermal sterilization in diluted silver nitrate (AgNO3) solutions at 121 °C for 20 min. The effects of the AgNO3 concentration on the surface silver content, silver-containing partic...

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Main Authors: Lingli Xu, Honghao Pei, Qian Qian, Xingling Shi, Le Thi Bang, Boxuan Li, Yuxin Wang
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Journal of Materials Research and Technology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2238785424024888
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author Lingli Xu
Honghao Pei
Qian Qian
Xingling Shi
Le Thi Bang
Boxuan Li
Yuxin Wang
author_facet Lingli Xu
Honghao Pei
Qian Qian
Xingling Shi
Le Thi Bang
Boxuan Li
Yuxin Wang
author_sort Lingli Xu
collection DOAJ
description In this study, a silver-modified layer was prepared on pure titanium through alkaline-heat treatment followed by hydrothermal sterilization in diluted silver nitrate (AgNO3) solutions at 121 °C for 20 min. The effects of the AgNO3 concentration on the surface silver content, silver-containing particle distribution, and silver chemical state were investigated; the antibacterial properties of the surface-modified titanium samples against Staphylococcus aureus and their compatibility with MC3T3-E1 osteoblast-like cells were preliminarily evaluated. The results showed that the 3D network nanostructure constructed by alkaline-heat treatment on the pure titanium served as a matrix for the reduction of Ag+ ions to silver nanoparticles (AgNPs) during the hydrothermal sterilization process without the addition of a reducing agent. These AgNPs evenly distributed without aggregation, and as the AgNO3 concentration decreased from 10−2 mol/L to 10−6 mol/L, the number of AgNPs gradually decreased, but their size slightly changed. Silver-loaded surfaces exhibited good antibacterial and anti-adhesion properties. However, when the AgNO3 concentration was greater than 10−4 mol/L, the number of AgNPs on the surface was excessive, resulting in significant cytotoxicity. When the AgNO3 concentration was between 10−5 and 10−6 mol/L, good antibacterial activity and good cell compatibility were achieved synchronously.
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spelling doaj-art-bb8f31849f8a44ae981f9d2a0edc79532025-08-20T02:35:25ZengElsevierJournal of Materials Research and Technology2238-78542024-11-01335863587310.1016/j.jmrt.2024.10.217Fabrication of silver-containing antibacterial coating on titanium by alkaline-heat treatment and hydrothermal sterilizationLingli Xu0Honghao Pei1Qian Qian2Xingling Shi3Le Thi Bang4Boxuan Li5Yuxin Wang6School of Materials Science and Engineering, Jiangsu University of Science and Technology, Zhenjiang, 212100, ChinaSchool of Materials Science and Engineering, Jiangsu University of Science and Technology, Zhenjiang, 212100, ChinaSchool of Materials Science and Engineering, Jiangsu University of Science and Technology, Zhenjiang, 212100, ChinaSchool of Materials Science and Engineering, Jiangsu University of Science and Technology, Zhenjiang, 212100, China; Corresponding author.School of Material Science and Engineering, Hanoi University of Science and Technology, Hanoi, 10000, Viet NamDepartment of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ, 08854, United StatesSchool of Materials Science and Engineering, Jiangsu University of Science and Technology, Zhenjiang, 212100, China; Corresponding author.In this study, a silver-modified layer was prepared on pure titanium through alkaline-heat treatment followed by hydrothermal sterilization in diluted silver nitrate (AgNO3) solutions at 121 °C for 20 min. The effects of the AgNO3 concentration on the surface silver content, silver-containing particle distribution, and silver chemical state were investigated; the antibacterial properties of the surface-modified titanium samples against Staphylococcus aureus and their compatibility with MC3T3-E1 osteoblast-like cells were preliminarily evaluated. The results showed that the 3D network nanostructure constructed by alkaline-heat treatment on the pure titanium served as a matrix for the reduction of Ag+ ions to silver nanoparticles (AgNPs) during the hydrothermal sterilization process without the addition of a reducing agent. These AgNPs evenly distributed without aggregation, and as the AgNO3 concentration decreased from 10−2 mol/L to 10−6 mol/L, the number of AgNPs gradually decreased, but their size slightly changed. Silver-loaded surfaces exhibited good antibacterial and anti-adhesion properties. However, when the AgNO3 concentration was greater than 10−4 mol/L, the number of AgNPs on the surface was excessive, resulting in significant cytotoxicity. When the AgNO3 concentration was between 10−5 and 10−6 mol/L, good antibacterial activity and good cell compatibility were achieved synchronously.http://www.sciencedirect.com/science/article/pii/S2238785424024888TitaniumSilverAntibacterial propertyCell compatibility
spellingShingle Lingli Xu
Honghao Pei
Qian Qian
Xingling Shi
Le Thi Bang
Boxuan Li
Yuxin Wang
Fabrication of silver-containing antibacterial coating on titanium by alkaline-heat treatment and hydrothermal sterilization
Journal of Materials Research and Technology
Titanium
Silver
Antibacterial property
Cell compatibility
title Fabrication of silver-containing antibacterial coating on titanium by alkaline-heat treatment and hydrothermal sterilization
title_full Fabrication of silver-containing antibacterial coating on titanium by alkaline-heat treatment and hydrothermal sterilization
title_fullStr Fabrication of silver-containing antibacterial coating on titanium by alkaline-heat treatment and hydrothermal sterilization
title_full_unstemmed Fabrication of silver-containing antibacterial coating on titanium by alkaline-heat treatment and hydrothermal sterilization
title_short Fabrication of silver-containing antibacterial coating on titanium by alkaline-heat treatment and hydrothermal sterilization
title_sort fabrication of silver containing antibacterial coating on titanium by alkaline heat treatment and hydrothermal sterilization
topic Titanium
Silver
Antibacterial property
Cell compatibility
url http://www.sciencedirect.com/science/article/pii/S2238785424024888
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