Gene network centrality analysis identifies key regulators coordinating day-night metabolic transitions in Synechococcus elongatus PCC 7942 despite limited accuracy in predicting direct regulator-gene interactions

Synechococcus elongatus PCC 7942 is a model organism for studying circadian regulation and bioproduction, where precise temporal control of metabolism significantly impacts photosynthetic efficiency and CO2-to-bioproduct conversion. Despite extensive research on core clock components, our understand...

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Bibliographic Details
Main Authors:	Zachary Johnson, David Anderson, Margaret S. Cheung, Pavlo Bohutskyi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-03-01
Series:	Frontiers in Microbiology
Subjects:	gene regulatory networks circadian regulation gene network centrality analysis regulation of day-night transition coordination of temporal metabolism network-based key regulator discovery
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2025.1569559/full
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Gene network centrality analysis identifies key regulators coordinating day-night metabolic transitions in Synechococcus elongatus PCC 7942 despite limited accuracy in predicting direct regulator-gene interactions

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