A map of human cancer signaling
Abstract We conducted a comprehensive analysis of a manually curated human signaling network containing 1634 nodes and 5089 signaling regulatory relations by integrating cancer‐associated genetically and epigenetically altered genes. We find that cancer mutated genes are enriched in positive signali...
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| Main Authors: | Qinghua Cui, Yun Ma, Maria Jaramillo, Hamza Bari, Arif Awan, Song Yang, Simo Zhang, Lixue Liu, Meng Lu, Maureen O'Connor‐McCourt, Enrico O Purisima, Edwin Wang |
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| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2007-12-01
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| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/msb4100200 |
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