Biofilm-forming and antimicrobial resistance traits of staphylococci isolated from goat dairy plants

Introduction: Biofilm-associated antimicrobial resistance is of increasing importance to the maintenance and spread of foodborne pathogens in the food industry. This study aimed to investigate the ability to form biofilm and the antimicrobial resistance of staphylococci contaminating small-scale goa...

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Main Authors: Myrella Cariry Lira, Paricia Emília Naves Givisiez, Francisca Geovânia Canafístula de Sousa, Marciane Magnani, Evandro Leite de Souza, Denis Augusto Spricigo, Wondwossen Abebe Gebreyes, Celso José Bruno de Oliveira
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2016-09-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/6714
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author Myrella Cariry Lira
Paricia Emília Naves Givisiez
Francisca Geovânia Canafístula de Sousa
Marciane Magnani
Evandro Leite de Souza
Denis Augusto Spricigo
Wondwossen Abebe Gebreyes
Celso José Bruno de Oliveira
author_facet Myrella Cariry Lira
Paricia Emília Naves Givisiez
Francisca Geovânia Canafístula de Sousa
Marciane Magnani
Evandro Leite de Souza
Denis Augusto Spricigo
Wondwossen Abebe Gebreyes
Celso José Bruno de Oliveira
author_sort Myrella Cariry Lira
collection DOAJ
description Introduction: Biofilm-associated antimicrobial resistance is of increasing importance to the maintenance and spread of foodborne pathogens in the food industry. This study aimed to investigate the ability to form biofilm and the antimicrobial resistance of staphylococci contaminating small-scale goat milk dairy plants. Methodology: Sixty isolates were tested for antimicrobial resistance against 20 drugs by the microdilution method. Biofilm-forming traits were assessed by the microtiter plate method (MtP), Congo red agar method (CRA), and icaD gene detection by polymerase chain reaction (PCR). Results: High antimicrobial resistance to ampicillin (60/60; 100%), penicillin G (21/60; 35%), and erythromycin (15/60; 25%) was observed, but all isolates were susceptible to amoxicillin/K-clavulanate, ceftriaxone, ciprofloxacin, gentamicin, levofloxacin, linezolid, and moxifloxacin. No resistance to oxacillin or vancomycin was seen among Staphylococcus aureus. Twenty-seven isolates (27/60; 45%) were considered to form biofilm according to MtP, and similar biofilm-producing frequencies were observed in coagulase-negative staphylococci (CoNS) (20/44; 45.4%) and S. aureus (7/16; 43.7%). The icaD gene was observed only in S. aureus isolates. There was no association between biofilm production and antimicrobial resistance. A higher frequency of biofilm-producing staphylococci was found in isolates from bulk tank milk and hand swabs. On the other hand, isolates from pasteurized milk showed lower frequency of biofilm formation. Conclusions: Staphylococci contaminating goat dairy plants are potential biofilm producers. The results suggest no association between the ability to form biofilm and antimicrobial resistance.
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publisher The Journal of Infection in Developing Countries
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spelling doaj-art-bb7d77120afe4b5b98cd756a9700370d2025-08-20T02:27:11ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802016-09-01100910.3855/jidc.6714Biofilm-forming and antimicrobial resistance traits of staphylococci isolated from goat dairy plantsMyrella Cariry Lira0Paricia Emília Naves Givisiez1Francisca Geovânia Canafístula de Sousa2Marciane Magnani3Evandro Leite de Souza4Denis Augusto Spricigo5Wondwossen Abebe Gebreyes6Celso José Bruno de Oliveira7Center for Health Sciences, Federal University of Paraíba, João Pessoa, BrazilCenter for Agricultural Sciences, Federal University of Paraíba, Areia, BrazilCenter for Agricultural Sciences, Federal University of Paraíba, Areia, BrazilCenter for Technology, Federal University of Paraíba, João Pessoa, BrazilCenter for Health Sciences, Federal University of Paraíba, João Pessoa, BrazilMinistry of Agriculture and Food Supplies, Porto Alegre, BrazilCollege of Veterinary Medicine, The Ohio State University, Columbus, OH, United StatesCenter for Agricultural Sciences, Federal University of Paraíba, Areia, BrazilIntroduction: Biofilm-associated antimicrobial resistance is of increasing importance to the maintenance and spread of foodborne pathogens in the food industry. This study aimed to investigate the ability to form biofilm and the antimicrobial resistance of staphylococci contaminating small-scale goat milk dairy plants. Methodology: Sixty isolates were tested for antimicrobial resistance against 20 drugs by the microdilution method. Biofilm-forming traits were assessed by the microtiter plate method (MtP), Congo red agar method (CRA), and icaD gene detection by polymerase chain reaction (PCR). Results: High antimicrobial resistance to ampicillin (60/60; 100%), penicillin G (21/60; 35%), and erythromycin (15/60; 25%) was observed, but all isolates were susceptible to amoxicillin/K-clavulanate, ceftriaxone, ciprofloxacin, gentamicin, levofloxacin, linezolid, and moxifloxacin. No resistance to oxacillin or vancomycin was seen among Staphylococcus aureus. Twenty-seven isolates (27/60; 45%) were considered to form biofilm according to MtP, and similar biofilm-producing frequencies were observed in coagulase-negative staphylococci (CoNS) (20/44; 45.4%) and S. aureus (7/16; 43.7%). The icaD gene was observed only in S. aureus isolates. There was no association between biofilm production and antimicrobial resistance. A higher frequency of biofilm-producing staphylococci was found in isolates from bulk tank milk and hand swabs. On the other hand, isolates from pasteurized milk showed lower frequency of biofilm formation. Conclusions: Staphylococci contaminating goat dairy plants are potential biofilm producers. The results suggest no association between the ability to form biofilm and antimicrobial resistance. https://jidc.org/index.php/journal/article/view/6714antibioticbiofilmica geneslimeStaphylococcus
spellingShingle Myrella Cariry Lira
Paricia Emília Naves Givisiez
Francisca Geovânia Canafístula de Sousa
Marciane Magnani
Evandro Leite de Souza
Denis Augusto Spricigo
Wondwossen Abebe Gebreyes
Celso José Bruno de Oliveira
Biofilm-forming and antimicrobial resistance traits of staphylococci isolated from goat dairy plants
Journal of Infection in Developing Countries
antibiotic
biofilm
ica gene
slime
Staphylococcus
title Biofilm-forming and antimicrobial resistance traits of staphylococci isolated from goat dairy plants
title_full Biofilm-forming and antimicrobial resistance traits of staphylococci isolated from goat dairy plants
title_fullStr Biofilm-forming and antimicrobial resistance traits of staphylococci isolated from goat dairy plants
title_full_unstemmed Biofilm-forming and antimicrobial resistance traits of staphylococci isolated from goat dairy plants
title_short Biofilm-forming and antimicrobial resistance traits of staphylococci isolated from goat dairy plants
title_sort biofilm forming and antimicrobial resistance traits of staphylococci isolated from goat dairy plants
topic antibiotic
biofilm
ica gene
slime
Staphylococcus
url https://jidc.org/index.php/journal/article/view/6714
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