First Report of CTX-M-14 Producing Clinical Isolates of Salmonella serovar Typhimurium from Egypt.
Three pediatric isolates of Salmonella serovar Typhimurium from Egypt were reported as CTX-M-14 ESBL producers. Two of the 3 isolates (68 and 111) were 85% related by PFGE;however both were distinct from isolate 94. All three isolates produced multiple clavulanate sensitive β-lactamase bands on IEF...
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The Journal of Infection in Developing Countries
2009-12-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/386 |
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| author | Sameh M.M. AbdelGhani Ellen Smith Moland Jennifer A. Black Nancy D. Hanson Richard V. Goering Magdy A. Amine Amal E. Saafan Maha Gaafar Mariam Younan Kenneth S. Thomson |
| author_facet | Sameh M.M. AbdelGhani Ellen Smith Moland Jennifer A. Black Nancy D. Hanson Richard V. Goering Magdy A. Amine Amal E. Saafan Maha Gaafar Mariam Younan Kenneth S. Thomson |
| author_sort | Sameh M.M. AbdelGhani |
| collection | DOAJ |
| description | Three pediatric isolates of Salmonella serovar Typhimurium from Egypt were reported as
CTX-M-14 ESBL producers. Two of the 3 isolates (68 and 111) were 85% related by PFGE;however both were distinct from isolate 94. All three isolates produced multiple clavulanate sensitive β-lactamase bands on IEF with pIs of 7.9 and 5.4 (all isolates), while pI 8.2 enzyme was produced by isolate 94 and pI 7.4 enzyme by isolate 111. The pI 7.9 enzyme was transferable by conjugation and conferred a CTX-M ESBL phenotype. PCR and sequencing identified the CTX-M gene as CTX-M-14. Genes for OXA-1 and SHV-12 were also identified by sequencing. To our knowledge this is the first report of CTX-M-producing Salmonella in Egypt.
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| format | Article |
| id | doaj-art-bb7738be53a548a58658a402d2c4d777 |
| institution | Kabale University |
| issn | 1972-2680 |
| language | English |
| publishDate | 2009-12-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-bb7738be53a548a58658a402d2c4d7772025-08-20T03:48:58ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802009-12-0140110.3855/jidc.386First Report of CTX-M-14 Producing Clinical Isolates of Salmonella serovar Typhimurium from Egypt.Sameh M.M. AbdelGhani0Ellen Smith Moland1Jennifer A. Black2Nancy D. Hanson3Richard V. Goering4Magdy A. Amine5Amal E. Saafan6Maha Gaafar7Mariam Younan8Kenneth S. Thomson9Cairo University School of PharmacyCreighton University School of MedicineCreighton University School of MedicineCreighton University School of MedicineCreighton University School of MedicineCairo University School of PharmacyBeni-Seif University School of PharmacyCairo University School of MedicineCairo University School of MedicineCreighton University School of MedicineThree pediatric isolates of Salmonella serovar Typhimurium from Egypt were reported as CTX-M-14 ESBL producers. Two of the 3 isolates (68 and 111) were 85% related by PFGE;however both were distinct from isolate 94. All three isolates produced multiple clavulanate sensitive β-lactamase bands on IEF with pIs of 7.9 and 5.4 (all isolates), while pI 8.2 enzyme was produced by isolate 94 and pI 7.4 enzyme by isolate 111. The pI 7.9 enzyme was transferable by conjugation and conferred a CTX-M ESBL phenotype. PCR and sequencing identified the CTX-M gene as CTX-M-14. Genes for OXA-1 and SHV-12 were also identified by sequencing. To our knowledge this is the first report of CTX-M-producing Salmonella in Egypt. https://jidc.org/index.php/journal/article/view/386CTX-M ESBLsEnterobacteriaceaeEgypt |
| spellingShingle | Sameh M.M. AbdelGhani Ellen Smith Moland Jennifer A. Black Nancy D. Hanson Richard V. Goering Magdy A. Amine Amal E. Saafan Maha Gaafar Mariam Younan Kenneth S. Thomson First Report of CTX-M-14 Producing Clinical Isolates of Salmonella serovar Typhimurium from Egypt. Journal of Infection in Developing Countries CTX-M ESBLs Enterobacteriaceae Egypt |
| title | First Report of CTX-M-14 Producing Clinical Isolates of Salmonella serovar Typhimurium from Egypt. |
| title_full | First Report of CTX-M-14 Producing Clinical Isolates of Salmonella serovar Typhimurium from Egypt. |
| title_fullStr | First Report of CTX-M-14 Producing Clinical Isolates of Salmonella serovar Typhimurium from Egypt. |
| title_full_unstemmed | First Report of CTX-M-14 Producing Clinical Isolates of Salmonella serovar Typhimurium from Egypt. |
| title_short | First Report of CTX-M-14 Producing Clinical Isolates of Salmonella serovar Typhimurium from Egypt. |
| title_sort | first report of ctx m 14 producing clinical isolates of salmonella serovar typhimurium from egypt |
| topic | CTX-M ESBLs Enterobacteriaceae Egypt |
| url | https://jidc.org/index.php/journal/article/view/386 |
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