Determining respiratory rate from photoplethysmogram and electrocardiogram signals using respiratory quality indices and neural networks.

Continuous and non-invasive respiratory rate (RR) monitoring would significantly improve patient outcomes. Currently, RR is under-recorded in clinical environments and is often measured by manually counting breaths. In this work, we investigate the use of respiratory signal quality quantification an...

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Main Authors: Stephanie Baker, Wei Xiang, Ian Atkinson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0249843&type=printable
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author Stephanie Baker
Wei Xiang
Ian Atkinson
author_facet Stephanie Baker
Wei Xiang
Ian Atkinson
author_sort Stephanie Baker
collection DOAJ
description Continuous and non-invasive respiratory rate (RR) monitoring would significantly improve patient outcomes. Currently, RR is under-recorded in clinical environments and is often measured by manually counting breaths. In this work, we investigate the use of respiratory signal quality quantification and several neural network (NN) structures for improved RR estimation. We extract respiratory modulation signals from the electrocardiogram (ECG) and photoplethysmogram (PPG) signals, and calculate a possible RR from each extracted signal. We develop a straightforward and efficient respiratory quality index (RQI) scheme that determines the quality of each moonddulation-extracted respiration signal. We then develop NNs for the estimation of RR, using estimated RRs and their corresponding quality index as input features. We determine that calculating RQIs for modulation-extracted RRs decreased the mean absolute error (MAE) of our NNs by up to 38.17%. When trained and tested using 60-sec waveform segments, the proposed scheme achieved an MAE of 0.638 breaths per minute. Based on these results, our scheme could be readily implemented into non-invasive wearable devices for continuous RR measurement in many healthcare applications.
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spelling doaj-art-bb76ac8cfecc48aeaf7c79b74f2f23082025-08-20T02:54:28ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-01164e024984310.1371/journal.pone.0249843Determining respiratory rate from photoplethysmogram and electrocardiogram signals using respiratory quality indices and neural networks.Stephanie BakerWei XiangIan AtkinsonContinuous and non-invasive respiratory rate (RR) monitoring would significantly improve patient outcomes. Currently, RR is under-recorded in clinical environments and is often measured by manually counting breaths. In this work, we investigate the use of respiratory signal quality quantification and several neural network (NN) structures for improved RR estimation. We extract respiratory modulation signals from the electrocardiogram (ECG) and photoplethysmogram (PPG) signals, and calculate a possible RR from each extracted signal. We develop a straightforward and efficient respiratory quality index (RQI) scheme that determines the quality of each moonddulation-extracted respiration signal. We then develop NNs for the estimation of RR, using estimated RRs and their corresponding quality index as input features. We determine that calculating RQIs for modulation-extracted RRs decreased the mean absolute error (MAE) of our NNs by up to 38.17%. When trained and tested using 60-sec waveform segments, the proposed scheme achieved an MAE of 0.638 breaths per minute. Based on these results, our scheme could be readily implemented into non-invasive wearable devices for continuous RR measurement in many healthcare applications.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0249843&type=printable
spellingShingle Stephanie Baker
Wei Xiang
Ian Atkinson
Determining respiratory rate from photoplethysmogram and electrocardiogram signals using respiratory quality indices and neural networks.
PLoS ONE
title Determining respiratory rate from photoplethysmogram and electrocardiogram signals using respiratory quality indices and neural networks.
title_full Determining respiratory rate from photoplethysmogram and electrocardiogram signals using respiratory quality indices and neural networks.
title_fullStr Determining respiratory rate from photoplethysmogram and electrocardiogram signals using respiratory quality indices and neural networks.
title_full_unstemmed Determining respiratory rate from photoplethysmogram and electrocardiogram signals using respiratory quality indices and neural networks.
title_short Determining respiratory rate from photoplethysmogram and electrocardiogram signals using respiratory quality indices and neural networks.
title_sort determining respiratory rate from photoplethysmogram and electrocardiogram signals using respiratory quality indices and neural networks
url https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0249843&type=printable
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AT ianatkinson determiningrespiratoryratefromphotoplethysmogramandelectrocardiogramsignalsusingrespiratoryqualityindicesandneuralnetworks