Comparison of hybrid coronary revascularization versus conventional Coronary Artery Bypass surgery in patients with multi-vessel coronary artery disease in a real-world setting: In-hospital outcomes and medium-term follow-up: COHOS study
Objectives: The aim of this observational study was to evaluate the in-hospital and medium-term outcomes of hybrid coronary revascularization (HCR) in the real-world setting compared to conventional coronary artery bypass grafting (CABG). Methods: All patients with multi-vessel coronary artery disea...
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Elsevier
2025-03-01
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| Series: | Indian Heart Journal |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0019483225000483 |
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| author | Dhamodaran Kaliyamoorthy Meeranghani Mohamed Yusuf Vadivelu Ramalingam Abhishek Kasha Manickam Kathiresan Rizwan Suliankatchi Abdulkader Jeyashree Kathiresan Aishwarya Mahesh Kumar Elsa Grace Anirban Choudhury |
| author_facet | Dhamodaran Kaliyamoorthy Meeranghani Mohamed Yusuf Vadivelu Ramalingam Abhishek Kasha Manickam Kathiresan Rizwan Suliankatchi Abdulkader Jeyashree Kathiresan Aishwarya Mahesh Kumar Elsa Grace Anirban Choudhury |
| author_sort | Dhamodaran Kaliyamoorthy |
| collection | DOAJ |
| description | Objectives: The aim of this observational study was to evaluate the in-hospital and medium-term outcomes of hybrid coronary revascularization (HCR) in the real-world setting compared to conventional coronary artery bypass grafting (CABG). Methods: All patients with multi-vessel coronary artery disease (MV-CAD) who underwent conventional CABG and HCR in our institution between January 2018 to January 2021 were evaluated in terms of length of intensive care unit (ICU), in-hospital stay, repeat revascularization rates, bleeding, stroke, and in-hospital mortality. Clinical outcomes (mortality and major adverse cardiac and cerebrovascular events [MACCE]) were assessed at average follow up of 3.6 years. Results: Pre-procedural characteristics were balanced between the groups after propensity score matching. There was no significant difference in MACCE [Odds ratio: 0.57; 95 % CI: 0.05 to 1.52; p = 0.66], in-hospital mortality [n = 2 (1.9 %) vs n = 0; p = 0.80], post procedure stroke [n = 2 (1.9 %) vs n = 2 (3.7 %); p = 0.86], post-procedural myocardial infarction requiring repeat revascularization [n = 2 (1.9 %) versus n = 1 (1.9 %); p = 1] during the in-hospital stay of the patients in the CABG vs HCR groups respectively. HCR was associated with significantly lower requirement for blood transfusions, bleeding risk, in-hospital stay, and intensive care unit stay. Analysis of the outcomes after 3.6 years revealed no significant difference in MACCE [Odds ratio: 1.40; 95 % CI: 0.46 to 4.30; p = 0.55], and post discharge mortality [n = 0 vs n = 0; p = 1]. Both groups had similar rates of post-procedural myocardial infarction requiring repeat revascularization [n = 0 vs n = 4 (7.4 %); p = 0.278], and rate of re-intervention [n = 0 vs n = 3 (5.6 %); p = 0.41]. Conclusion: HCR may be considered as a safe and feasible alternative to conventional CABG in selected individuals with MV-CAD. |
| format | Article |
| id | doaj-art-bb75073f984e46e896f3f0cdb65b2b6d |
| institution | Kabale University |
| issn | 0019-4832 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
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| series | Indian Heart Journal |
| spelling | doaj-art-bb75073f984e46e896f3f0cdb65b2b6d2025-08-20T03:47:31ZengElsevierIndian Heart Journal0019-48322025-03-017729810410.1016/j.ihj.2025.03.002Comparison of hybrid coronary revascularization versus conventional Coronary Artery Bypass surgery in patients with multi-vessel coronary artery disease in a real-world setting: In-hospital outcomes and medium-term follow-up: COHOS studyDhamodaran Kaliyamoorthy0Meeranghani Mohamed Yusuf1Vadivelu Ramalingam2Abhishek Kasha3Manickam Kathiresan4Rizwan Suliankatchi Abdulkader5Jeyashree Kathiresan6Aishwarya Mahesh Kumar7Elsa Grace8Anirban Choudhury9Apollo Hospitals, Greams Road, Chennai - 600006, India; Corresponding author. Apollo Hospitals, Chennai – 600006, India.Apollo Hospitals, Greams Road, Chennai - 600006, IndiaDepartment of Cardiology, Velammal Medical College Hospital, Madurai, Tamil Nadu, 625009, IndiaApollo Hospitals, Greams Road, Chennai - 600006, IndiaApollo Hospitals, Greams Road, Chennai - 600006, IndiaNational Institute of Epidemiology, Indian Council of Medical Research, Second Main Road, Tamil Nadu Housing Board, Ayapakkam, Chennai - 600077, IndiaNational Institute of Epidemiology, Indian Council of Medical Research, Second Main Road, Tamil Nadu Housing Board, Ayapakkam, Chennai - 600077, IndiaApollo Hospitals, Greams Road, Chennai - 600006, IndiaApollo Hospitals, Greams Road, Chennai - 600006, IndiaMorriston Cardiac Centre, Swansea, United KingdomObjectives: The aim of this observational study was to evaluate the in-hospital and medium-term outcomes of hybrid coronary revascularization (HCR) in the real-world setting compared to conventional coronary artery bypass grafting (CABG). Methods: All patients with multi-vessel coronary artery disease (MV-CAD) who underwent conventional CABG and HCR in our institution between January 2018 to January 2021 were evaluated in terms of length of intensive care unit (ICU), in-hospital stay, repeat revascularization rates, bleeding, stroke, and in-hospital mortality. Clinical outcomes (mortality and major adverse cardiac and cerebrovascular events [MACCE]) were assessed at average follow up of 3.6 years. Results: Pre-procedural characteristics were balanced between the groups after propensity score matching. There was no significant difference in MACCE [Odds ratio: 0.57; 95 % CI: 0.05 to 1.52; p = 0.66], in-hospital mortality [n = 2 (1.9 %) vs n = 0; p = 0.80], post procedure stroke [n = 2 (1.9 %) vs n = 2 (3.7 %); p = 0.86], post-procedural myocardial infarction requiring repeat revascularization [n = 2 (1.9 %) versus n = 1 (1.9 %); p = 1] during the in-hospital stay of the patients in the CABG vs HCR groups respectively. HCR was associated with significantly lower requirement for blood transfusions, bleeding risk, in-hospital stay, and intensive care unit stay. Analysis of the outcomes after 3.6 years revealed no significant difference in MACCE [Odds ratio: 1.40; 95 % CI: 0.46 to 4.30; p = 0.55], and post discharge mortality [n = 0 vs n = 0; p = 1]. Both groups had similar rates of post-procedural myocardial infarction requiring repeat revascularization [n = 0 vs n = 4 (7.4 %); p = 0.278], and rate of re-intervention [n = 0 vs n = 3 (5.6 %); p = 0.41]. Conclusion: HCR may be considered as a safe and feasible alternative to conventional CABG in selected individuals with MV-CAD.http://www.sciencedirect.com/science/article/pii/S0019483225000483Hybrid coronary revascularizationCoronary Artery Bypass graftPercutaneous coronary interventionRobotic surgical procedures |
| spellingShingle | Dhamodaran Kaliyamoorthy Meeranghani Mohamed Yusuf Vadivelu Ramalingam Abhishek Kasha Manickam Kathiresan Rizwan Suliankatchi Abdulkader Jeyashree Kathiresan Aishwarya Mahesh Kumar Elsa Grace Anirban Choudhury Comparison of hybrid coronary revascularization versus conventional Coronary Artery Bypass surgery in patients with multi-vessel coronary artery disease in a real-world setting: In-hospital outcomes and medium-term follow-up: COHOS study Indian Heart Journal Hybrid coronary revascularization Coronary Artery Bypass graft Percutaneous coronary intervention Robotic surgical procedures |
| title | Comparison of hybrid coronary revascularization versus conventional Coronary Artery Bypass surgery in patients with multi-vessel coronary artery disease in a real-world setting: In-hospital outcomes and medium-term follow-up: COHOS study |
| title_full | Comparison of hybrid coronary revascularization versus conventional Coronary Artery Bypass surgery in patients with multi-vessel coronary artery disease in a real-world setting: In-hospital outcomes and medium-term follow-up: COHOS study |
| title_fullStr | Comparison of hybrid coronary revascularization versus conventional Coronary Artery Bypass surgery in patients with multi-vessel coronary artery disease in a real-world setting: In-hospital outcomes and medium-term follow-up: COHOS study |
| title_full_unstemmed | Comparison of hybrid coronary revascularization versus conventional Coronary Artery Bypass surgery in patients with multi-vessel coronary artery disease in a real-world setting: In-hospital outcomes and medium-term follow-up: COHOS study |
| title_short | Comparison of hybrid coronary revascularization versus conventional Coronary Artery Bypass surgery in patients with multi-vessel coronary artery disease in a real-world setting: In-hospital outcomes and medium-term follow-up: COHOS study |
| title_sort | comparison of hybrid coronary revascularization versus conventional coronary artery bypass surgery in patients with multi vessel coronary artery disease in a real world setting in hospital outcomes and medium term follow up cohos study |
| topic | Hybrid coronary revascularization Coronary Artery Bypass graft Percutaneous coronary intervention Robotic surgical procedures |
| url | http://www.sciencedirect.com/science/article/pii/S0019483225000483 |
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