Orbital and peri-ocular paraffinoma: case series and literature review

Abstract Background Paraffinoma is a rare and intriguing condition in medicine. In this disorder, an orbital lipogranulomatosis reaction is caused by the penetration of mineral oils (particularly paraffin) into the tissues surrounding the eye. Methods In this report, we discuss six cases of paraffin...

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Main Authors: Naser Owji, Zahra Zia, Farima Safari, Elham Sadeghi, Fatemeh Ebrahimi, Afrooz Feili, Mohammad Hassan Jalalpour, Behzad Khademi
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Ophthalmology
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Online Access:https://doi.org/10.1186/s12886-024-03736-8
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author Naser Owji
Zahra Zia
Farima Safari
Elham Sadeghi
Fatemeh Ebrahimi
Afrooz Feili
Mohammad Hassan Jalalpour
Behzad Khademi
author_facet Naser Owji
Zahra Zia
Farima Safari
Elham Sadeghi
Fatemeh Ebrahimi
Afrooz Feili
Mohammad Hassan Jalalpour
Behzad Khademi
author_sort Naser Owji
collection DOAJ
description Abstract Background Paraffinoma is a rare and intriguing condition in medicine. In this disorder, an orbital lipogranulomatosis reaction is caused by the penetration of mineral oils (particularly paraffin) into the tissues surrounding the eye. Methods In this report, we discuss six cases of paraffinoma affecting the eye socket following sinus surgery. For previous cases literature review, we obtained articles from searching in the PubMed, Scopus, Scholar Google and, Science of Web databases. Results After the reporting of 6 paraffinoma cases and literature review, the data related to the disease were categorized into the categories of disease definition, differential diagnosis, clinical manifestation, radiological manifestation, and histopathological diagnosis and treatment methods. Conclusions Paraffinoma is a rare and time-delayed diagnosis after various surgeries and therefore may challenge the physician to make the correct diagnosis at first. It is necessary for ophthalmologists to consider this diagnosis in cases of masses around the eyelid and orbit in patients with a history of sinus and nose surgery in other differential diagnoses.
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publishDate 2024-11-01
publisher BMC
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series BMC Ophthalmology
spelling doaj-art-bb5ed4ab3e5b430f82e4f60815fff14a2025-08-20T03:08:40ZengBMCBMC Ophthalmology1471-24152024-11-012411710.1186/s12886-024-03736-8Orbital and peri-ocular paraffinoma: case series and literature reviewNaser Owji0Zahra Zia1Farima Safari2Elham Sadeghi3Fatemeh Ebrahimi4Afrooz Feili5Mohammad Hassan Jalalpour6Behzad Khademi7Poostchi Ophthalmology Research Center, Shiraz University of Medical SciencesOphthalmology Department, Jahrom University of Medical SciencesSchool of Medicine, Shiraz University of Medical SciencesPoostchi Ophthalmology Research Center, Shiraz University of Medical SciencesPoostchi Ophthalmology Research Center, Shiraz University of Medical SciencesPoostchi Ophthalmology Research Center, Shiraz University of Medical SciencesPoostchi Ophthalmology Research Center, Shiraz University of Medical SciencesPoostchi Ophthalmology Research Center, Shiraz University of Medical SciencesAbstract Background Paraffinoma is a rare and intriguing condition in medicine. In this disorder, an orbital lipogranulomatosis reaction is caused by the penetration of mineral oils (particularly paraffin) into the tissues surrounding the eye. Methods In this report, we discuss six cases of paraffinoma affecting the eye socket following sinus surgery. For previous cases literature review, we obtained articles from searching in the PubMed, Scopus, Scholar Google and, Science of Web databases. Results After the reporting of 6 paraffinoma cases and literature review, the data related to the disease were categorized into the categories of disease definition, differential diagnosis, clinical manifestation, radiological manifestation, and histopathological diagnosis and treatment methods. Conclusions Paraffinoma is a rare and time-delayed diagnosis after various surgeries and therefore may challenge the physician to make the correct diagnosis at first. It is necessary for ophthalmologists to consider this diagnosis in cases of masses around the eyelid and orbit in patients with a history of sinus and nose surgery in other differential diagnoses.https://doi.org/10.1186/s12886-024-03736-8ParaffinomaForeign-body reactionSinus endoscopyComplicationDacryocystorhinostomy
spellingShingle Naser Owji
Zahra Zia
Farima Safari
Elham Sadeghi
Fatemeh Ebrahimi
Afrooz Feili
Mohammad Hassan Jalalpour
Behzad Khademi
Orbital and peri-ocular paraffinoma: case series and literature review
BMC Ophthalmology
Paraffinoma
Foreign-body reaction
Sinus endoscopy
Complication
Dacryocystorhinostomy
title Orbital and peri-ocular paraffinoma: case series and literature review
title_full Orbital and peri-ocular paraffinoma: case series and literature review
title_fullStr Orbital and peri-ocular paraffinoma: case series and literature review
title_full_unstemmed Orbital and peri-ocular paraffinoma: case series and literature review
title_short Orbital and peri-ocular paraffinoma: case series and literature review
title_sort orbital and peri ocular paraffinoma case series and literature review
topic Paraffinoma
Foreign-body reaction
Sinus endoscopy
Complication
Dacryocystorhinostomy
url https://doi.org/10.1186/s12886-024-03736-8
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